Results 241 to 250 of about 4,288 (305)

Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao   +23 more
wiley   +1 more source

A robust framework for evaluating green mines towards sustainable development. [PDF]

open access: yesSci Rep
Sayed E   +5 more
europepmc   +1 more source

A Comprehensive Review on Xylitol Production: Experimental and Theoretical Insights, Research Gaps, and Future Perspectives

open access: yesAdvanced Energy and Sustainability Research, Volume 7, Issue 6, June 2026.
This review integrates chemical and biological xylitol production from upstream to downstream, uniquely combining experimental and theoretical insights to reveal mechanisms, bottlenecks, and future directions for sustainable lignocellulosic xylitol production.
Tanongsak Sukkasem   +2 more
wiley   +1 more source

Modular Europium-Based Nanosensors for the Detection of Sodium and Potassium Ions. [PDF]

open access: yesACS Omega
Mendonsa AA   +8 more
europepmc   +1 more source

Desalinization and desodification efficiencies of phosphogypsum and leaching water in saline–sodic soils of Kessem, Ethiopia

open access: yesAgrosystems, Geosciences &Environment, Volume 9, Issue 2, June 2026.
Abstract Soil salinity and sodicity severely limit agricultural productivity in the Awash Basin of Ethiopia, demanding innovative reclamation strategies. This study evaluated the efficiency of phosphogypsum (PG) amendment at varying loadings under intermittent leaching using pore volume for saline–sodic clay loam soils at Kessem Sugar Estate, Ethiopia.
Gashaw Jifara Delesa   +3 more
wiley   +1 more source

Subterranean environments contribute to three‐quarters of classified ecosystem services

open access: yesBiological Reviews, Volume 101, Issue 3, Page 1582-1605, June 2026.
ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola   +30 more
wiley   +1 more source

Microbial diversity at remediated former gold and copper mines and the metal tolerance of indigenous microbial strains. [PDF]

open access: yesAppl Environ Microbiol
Velianyk V   +6 more
europepmc   +1 more source

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