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Lung Carcinogenicity of Sulfur Mustard
Clinical Lung Cancer, 2010Sulfur mustard (SM), a major potent chemical warfare agent, has been used for its acute toxic effects. Over time, unfortunately, many different long-term health effects of exposure to SM have been detected in humans. There are many available data from soldiers or civilians exposed to SM: testing programs, contaminated workers in factories who were ...
Mostafa, Ghanei, Ali Amini, Harandi
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Agents of chemical warfare: Sulfur mustard
Annals of Emergency Medicine, 1992Sulfur mustard is a chemical warfare agent of historical and current interest. Favored militarily because of its ability to incapacitate rather than its ability to kill, its use results in large numbers of casualties requiring prolonged, intensive care.
J, Borak, F R, Sidell
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Modeling for immunosupression by sulfur mustard
International Immunopharmacology, 2001The treatment and cure of patients exposed to sulfur mustard is a remaining challenge despite on-going research in this field. A severe suppression of the immune system still remains the major cause of opportunistic infections, septicemia and death in patients injured by sulfur mustard. In this report, we present a model of sulfur mustard contamination
Z M, Hassan, M, Ebtekar
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Immunological consequence of sulfur mustard exposure
Immunology Letters, 2002Global reports indicate that chemical weapons still impose a serious threat to world security and health. Sulfur mustard is a chemical compound with devastating short and long-term effect on human health.
Zuhaiar M, Hassan, Massoumeh, Ebtekar
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Tracheobronchial Stenosis Following Sulfur Mustard Inhalation
Inhalation Toxicology, 2004Sulfur mustard inhalation leads to different respiratory complications. In this article, we describe late stenotic effects of mustard gas inhalation on major airways. About 15 yr after exposure, suspect cases suffering from severe respiratory disorders underwent complete workup for central airway stenosis.
Mostafa, Ghanei +3 more
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Sulfur Mustard-Induced Ocular Surface Disorders
The Ocular Surface, 2011Sulfur mustard is a vesicant agent with severe irritating effects on living tissues, including skin, mucous membranes, eyes, and respiratory tract. The eyes are the most susceptible tissue to mustard gas effects, and varying degrees of ocular involvement are seen in 75% to 90% of exposed individuals. Most cases resolve uneventfully; however, a minority
Alireza, Baradaran-Rafii +2 more
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Antioxidants Countermeasures Against Sulfur Mustard
Mini-Reviews in Medicinal Chemistry, 2012Sulfur mustard (SM) is a vesicant chemical warfare agent that persists as a serious menace from the viewpoint of acute and chronic toxicity, simple synthesis and no effective treatment currently being available. The two most deleterious basic molecular mechanisms in SM poisoning are: inflammation and over-activation of poly(ADP-ribose) polymerase and ...
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Accidental sulfur mustard exposure: A case report
Toxicology Letters, 2018The clinical progression following a sulfur mustard-induced skin exposure is well documented in the literature. Upon skin contact and a characteristic latency period, sulfur mustard (SM) causes erythema, blister formation and ulceration, which is associated with wound healing disorders that may require surgical treatment. Here, we present a case report
Annette, Schmidt +4 more
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Phenyl sulfur mustard derivatives of distamycin A
Bioorganic & Medicinal Chemistry Letters, 2000The design, synthesis, and cytotoxic activity of novel benzoyl and cinnamoyl sulfur mustard derivatives of distamycin A are described and structure activity relationships are discussed. These sulfur mustards are more potent cytotoxics than corresponding nitrogen mustards in spite of the lower alkylating power, while their sulfoxide analogues are ...
P. Cozzi +6 more
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Other considerations about carcinogenicity of sulfur mustard
Cancer Causes & Control, 2013Dear Editor in Chief,We read with great interest a recently published article byZafarghandi et al. [1] in Cancer Cause and Control journal.In this long-term follow-up cohort study, the incidence ofcancer in Iranian sulfur mustard (SM)-exposed veteranswas assessed and reported in comparison with a matchedcontrol group.
Reza, Karbasi-Afshar +2 more
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