Results 181 to 190 of about 19,656 (225)
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Shapes of Sulfur, Oxygen, and Nitrogen Mustards
The Journal of Physical Chemistry A, 2011Thorough conformational analyses have been performed on representative sulfur, oxygen, and nitrogen mustards. A total of 23, 18, and 38 unique conformers have been located for SM, OM, and NM, respectively, at the MP2/aug-cc-pVDZ level of theory. Despite the fact that these molecules differ only in the identity of the central heteroatom, comparison of ...
Janos, Nadas +2 more
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Effect of sulfur mustard on murine lymphocytes
Toxicology Letters, 1991The effect on spleen cells of a single in vivo treatment with sulfur mustard was analyzed in mice 1 week after intoxication. A marked decrease in the number of total spleen cells was observed in mice receiving high doses of sulfur mustard. Flow cytometric analysis indicated that B-lymphocytes were relatively more affected than T-lymphocytes by this ...
J P, Coutelier +3 more
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Medical management of cutaneous sulfur mustard injuries
Toxicology, 2009Sulfur mustard (2,2'-dichlorodiethyl sulfide; HD) is a potent vesicating chemical warfare agent that poses a continuing threat to both military and civilian populations. Significant cutaneous HD injuries can take several months to heal, necessitate lengthy hospitalizations, and result in long-term complications.
John S, Graham +6 more
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Toxicodynamics of sulfur mustard.
International journal of clinical pharmacology, therapy, and toxicology, 1989Mustards have become an important topic of global discussion in recent years. The latest extensive reports and conference of 145 nations in Paris (January 13, 1989) reveal that several countries have stockpiled large quantities of mustard gas. This situation creates an imminent danger to accidental or intentional exposure of this gas to civil ...
S M, Somani, S R, Babu
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Sulfur mustard-induced poikiloderma: A case report
Cutaneous and Ocular Toxicology, 2010Sulfur mustard (SM) is a potent chemical warfare agent that was widely used during the First World War and the Iran-Iraq conflict. This vesicant agent causes several acute and chronic effects on the skin, eye, and respiratory system. We report the case of a 41-year-old man who was injured with SM in Iraq chemical attack in 1988.
Seyed Naser, Emadi +6 more
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Molecular Thioamide ↔ Iminothiolate Switches for Sulfur Mustards
Inorganic Chemistry, 2011SNS platinum(II) pincer complexes reversibly bind and release the surrogate half sulfur mustard, 2-chloroethyl ethyl sulfide (CEES). The switch-like behavior of the pincers is attributed to a reversible transformation between the thioamide and iminothiolate forms of the pincer skeleton under slightly acidic and basic conditions, respectively.
Qi-Qiang, Wang +3 more
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Detection of sulfur mustard-induced DNA modifications
Chemico-Biological Interactions, 1994Sulfur mustard is acutely toxic to the skin, eyes, and respiratory tract, and is considered carcinogenic to humans by the IARC. Since all of these toxicities are thought to be initiated by DNA alkylation, the level of DNA damage should serve as a biomarker for exposure.
D B, Ludlum +4 more
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Toxicokinetics of sulfur mustard
2016In this chapter an overview is presented on the state of knowledge concerning the toxicokinetics of sulfur mustard. The procedures to analyze intact sulfur mustard in the blood and tissues of laboratory animals at toxicologically relevant levels are discussed.
Langenberg, J.P. +2 more
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