Frontiers in OncologyIntroduction3 - Mercaptopyruvate Sulfurtransferase (3 - MST) is an enzyme encoded by the Mercaptopyruvate Sulfurtransferase (MPST) gene. The enzyme is associated with a variety of cancers such as lung adenocarcinoma.
Boran Cui +10 more
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Acta Pharmaceutica Sinica BThe catalytic activity of 3-mercaptopyruvate (3MP) sulfurtransferase (MPST) converts 3MP to hydrogen sulfide (H2S). However, the regulatory mechanisms governing MPST and its impact on the brain remain largely unexplored.
Li Zhu +13 more
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Involvement of the Azotobacter vinelandii Rhodanese-Like Protein RhdA in the Glutathione Regeneration Pathway [PDF]
, 2012 The phenotypic features of the Azotobacter vinelandii RhdA mutant MV474 (in which the rhdA gene was deleted) indicated that defects in antioxidant systems in this organism were related to the expression of the tandem-domain rhodanese RhdA.
Forlani, Fabio +5 more
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Activation of 3-Mercaptopyruvate Sulfurtransferase by Glutaredoxin Reducing System
Biomolecules, 2020 Glutaredoxin (EC 1.15–1.21) is known as an oxidoreductase that protects cysteine residues within proteins against oxidative stress. Glutaredoxin catalyzes an electron transfer reaction that donates an electron to substrate proteins in the reducing system
Noriyuki Nagahara
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Sulfurtransferases and Cystathionine Beta-Synthase Expression in Different Human Leukemia Cell Lines
Biomolecules, 2022 The studies concerned the expression of sulfurtransferases and cystathionine beta-synthase in six human leukemia cell lines: B cell acute lymphoblastic leukemia-B-ALL (REH cells), T cell acute lymphoblastic leukemia-T-ALL (DND-41 and MOLT-4 cells), acute
Halina Jurkowska +3 more
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Correction: <i>Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway</i>. [PDF]
Guteuropepmc +2 more sources
Radical <i>S</i>-Adenosylmethionine Sulfurtransferase MybB Catalyzed Formation of the 4-Thiazolidinone Core in Mycobacidin Represents an Intersection between Primary and Secondary Metabolism. [PDF]
J Am Chem SocMycobacidin is an antitubercular antibiotic structurally composed of a sulfur-containing 4-thiazolidinone ring, yet its biosynthesis including the mechanism of sulfur incorporation has remained an open question since its discovery in 1952. In this study,
Zhao H, Bu J, Liu HW.
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Hydrogen sulfide pathway and skeletal muscle: an introductory review. [PDF]
, 2018 The presence of the H2 S pathway in skeletal muscle (SKM) has recently been established. SKM expresses the three constitutive H2 S-generating enzymes in animals and humans, and it actively produces H2 S.
Armogida Chiara +2 more
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Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background [PDF]
, 2012 The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is ...
A Debrabant +85 more
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Expansion of Thaumarchaeota habitat range is correlated with horizontal transfer of ATPase operons. [PDF]
, 2019 Thaumarchaeota are responsible for a significant fraction of ammonia oxidation in the oceans and in soils that range from alkaline to acidic. However, the adaptive mechanisms underpinning their habitat expansion remain poorly understood.
Bartlett, Douglas H +24 more
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