Results 61 to 70 of about 9,691 (231)

Dosing-Time Dependent Effects of Sodium Nitroprusside on Cerebral, Renal, and Hepatic Catalase Activity in Mice [PDF]

, 2015
To investigate the time dependence of sodium nitroprusside- (NPS-) induced oxidative effects, the authors study the variation of the antioxidant enzyme CAT activity in various tissues after the administration of a single 2.5mg/kg dose of SNP or sodium ...
Ben-Attia, Mossadok, Boughattas, Naceur A., Ghanem-Boughanmi, Néziha, Mondal, Mohan, Refinetti, Roberto, Sani, Mamane, Sebai, Hichem   +6 more
core   +3 more sources

Acidity of persulfides and its modulation by the protein environments in sulfide quinone oxidoreductase and thiosulfate sulfurtransferase. [PDF]

J Biol Chem
Benchoam D, Cuevasanta E, Roman JV, Banerjee R, Alvarez B.   +4 more
europepmc   +2 more sources

Sulfanegen, a 3‐mercaptopyruvate sulfurtransferase substrate, as a therapeutic option for Alzheimer’s disease

Alzheimer's & Dementia, 2023
The oxidative stress evident in the Alzheimer’s disease (AD) brain leads to compromised 3‐mercaptopyruvate sulfurtransferase (3MST) function, one of the endogenous hydrogen sulfide (H2S) producing enzymes.1,2 Impaired 3MST function is expected to ...
Swati S. More, Swetha Pavani Rao, Wei Xie, C. Kwon, Nicholas Juckel, Robert Vince, Michael K. Lee   +6 more
semanticscholar   +1 more source

Mitochondrial Sulfide Detoxification Requires a Functional Isoform O-Acetylserine(thiol)lyase C in Arabidopsis thaliana [PDF]

, 2012
In non-cyanogenic species, the main source of cyanide derives from ethylene and camalexin biosyntheses. In mitochondria, cyanide is a potent inhibitor of the cytochrome c oxidase and is metabolised by the β-Cyanoalanine synthase CYS-C1, catalysing the ...
García Fernández, Irene, Gotor Martínez, Cecilia, Romero González, Luis Carlos, Álvarez Núñez, Consolación   +3 more
core   +1 more source

Sulfane sulfur deficiency in malignant cells, increasing the inhibiting action of acetone cyanohydrin in tumor growth [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To demonstrate the irreversible poisoning action of the acetone cyanohydrin (AC) in malignant cells. METHODS: Thirty male Swiss mice were inoculated with 1x10³ Ehrlich tumor (ET) cells. The mice were divided into three groups (n=10): CG (saline);
Rondon Tosta Ramalho, Ricardo Dutra Aydos, Iandara Schettert, Peterson Vieira de Assis, Pedro Carvalho Cassino   +4 more
doaj   +1 more source

Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. [PDF]

, 2006
Immunophilin is the collective name given to the cyclophilin and FK506-binding protein (FKBP) families. As the name suggests, these include the major binding proteins of certain immunosuppressive drugs: cyclophilins for the cyclic peptide cyclosporin A ...
Adams, Aliberti, Alphey, Angus Bell, Antony P. Page, Argaet, Banerjee, Banumathy, Belfiore, Bell, Bell, Bell, Berriman, Blumenthal, Blumenthal, Borel, Bozdech, Braun, Bua, Carlton, Chakraborty, Chakraborty, Chappell, Chappell, Cianciotto, Cohen, Colgan, Dao-Thi, Denkers, Dobson, Dolinski, Dornan, Dornan, Dutta, Fischer, Florens, Galat, Galat, Gavigan, Gavigan, Gilleard, Golding, Hacker, Hall, High, Hirtzlin, Hong, Hope, Kamath, Kay, Ke, Khattab, Kiang, Klinkert, Klinkert, Knobloch, Kumar, Kumar, Kumar, Le Roch, Lightowlers, Lorberg, Ma, Ma, Ma, Matsuda, McLauchlan, Mikol, Monaghan, Monaghan, Moro, Osman, Ostoa-Saloma, Oz, Page, Page, Page, Page, Page, Page, Page, Paul Monaghan, Pelle, Pereira, Peterson, Picken, Pratt, Rascher, Reddy, Riggs, Rossi, Shirane, Silverman, Taylor, Tuo, Valle, Wang, Weiwad, Williams, Yarovinsky, Yu, Zorio   +101 more
core   +1 more source

Characterization of Mycobacterium tuberculosis rhodanese-like sulfurtransferase SseA and its newly identified activator Rv3284: A new pathway to exploit as a drug target?

bioRxiv
Tuberculosis (TB) remains a critical global health challenge, with Mycobacterium tuberculosis (Mtb) causing 10.8 million cases and 1.25 million deaths in 2023.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, S. Oliaro‐Bosso, A. Ruggiero, Rita Berisio, Milagros Medina, A. Velázquez‐Campoy, S. Adinolfi, Mauro Marengo   +10 more
semanticscholar   +1 more source

Implications of hydrogen sulfide in liver pathophysiology: Mechanistic insights and therapeutic potential

Journal of Advanced Research, 2021
Background: Over the last several decades, hydrogen sulfide (H2S) has been found to exert multiple physiological functions in mammal systems. The endogenous production of H2S is primarily mediated by cystathione β-synthase (CBS), cystathione γ-lyase (CSE)
Hai-Jian Sun, Zhi-Yuan Wu, Xiao-Wei Nie, Xin-Yu Wang, Jin-Song Bian   +4 more
doaj   +1 more source

In Vivo Anti-inflammatory Activity of Lipoic Acid Derivatives in Mice  [PDF]

, 2013
Background: In mammals lipoic acid (LA) and its reduced form dihydrolipoic acid (DHLA) function as cofactors for multienzymatic complexes catalyzing the decarboxylation of α-ketoacids.
Anna Bilska-Wilkosz, Brunon Kwiecień, Inga Kwiecień, Jacek Sapa, Joanna Knutelska, Lidia Włodek, Magdalena Dudek, Marek Bednarski, Maria Sokołowska-Jeżewicz, Małgorzata Iciek, Małgorzata Zygmunt   +10 more
core   +1 more source

3‐Mercaptopyruvate sulfurtransferase represses tumour progression and predicts prognosis in hepatocellular carcinoma

Liver international (Print), 2022
The prognosis of hepatocellular carcinoma (HCC) remains dismal, and its molecular pathogenesis has not been completely defined. The enzyme 3‐mercaptopyruvate sulfurtransferase (MPST) regulates endogenous hydrogen sulfide (H2S) biosynthesis.
Meng Li, Xin Song, Qingzhi Jin, Yishu Chen, Jie Zhang, Jianguo Gao, Li Cen, Yiming Lin, Chengfu Xu, Xinjue He, Youming Li, Chaohui Yu   +11 more
semanticscholar   +1 more source