Results 31 to 40 of about 769 (137)

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers, Isabel O. de Moya Clark, Tomás Cavaco, Vivian Nemanič, Beatrice Tagliabue, Ainhoa Valero‐Abad, Wiebe M. Wennekers, Mengqiu Zhang, Koen Van Zwet, Sanne Abeln, Sofia Moco, Caroline E. Paul, Halima Mouhib, Richard A. Notebaart, Eddy J. Smid, Bas Teusink, Herwig Bachmann   +16 more
wiley   +1 more source

Histone Deacetylase 9 Gene Deletion Ameliorates Aging‐Related Adipose Tissue Senescence and Mitochondrial Dysfunction in Mice

Aging Cell, Volume 25, Issue 5, May 2026.
Cellular senescence and mitochondrial dysfunction disrupt adipose tissue homeostasis during aging, but mechanisms remain unclear. HDAC9 expression increases with age in mouse adipose tissue and Hdac9 knockout mice showed reduced fat mass, senescence markers, and enhanced mitochondrial gene expression, respiration, and thiosulfate sulfurtransferase (Tst)
Brandee Goo, Samah Ahmadieh, Praneet Veerapaneni, Hong Shi, David S. Kim, Mourad Ogbi, Ronnie Chouhaita, Nicole Cyriac, Stephen Cave, Lingling Liu, Yong Zhang, Quansheng Du, Ha Won Kim, Yun Lei, Xin‐Yun Lu, Neal L. Weintraub   +15 more
wiley   +1 more source

Characterization of a sulfurtransferase from Arabidopsis thaliana [PDF]

European Journal of Biochemistry, 2000
A database search for similarities between sequenced parts of the Arabidopsis thaliana genome with known sulfurtransferase sequences from Escherichia coli and mammals was undertaken to obtain information about plant sulfurtransferase‐like proteins. One gene and several homologous EST clones were identified.
J, Papenbrock, A, Schmidt
openaire   +2 more sources

Novel roles of sulfur metabolism in stress‐controlled stomata aperture regulation

New Phytologist, Volume 250, Issue 3, Page 1460-1467, May 2026.
Summary Stomatal closure allows plants to conserve water by reducing transpiration during drought. Surprisingly, the assimilation of the macronutrient sulfur is intimately connected to the drought stress response. This Tansley insight will only briefly touch on the general impact of sulfate assimilation on the production of drought‐response metabolites.
Sheng‐Kai Sun, Rüdiger Hell, Markus Wirtz   +2 more
wiley   +1 more source

Identification and Characterisation of the Gene Cluster Governing Biosynthesis of the Anti‐Mycobacterial Antibiotic Acidomycin

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
Biosynthetic gene cluster for antibiotic acidomycin targeting biotin biosynthesis in mycobacteria was identified in a Streptomyces bacterium, and its identity was confirmed by gene knockout and heterologous expression. This cluster is located in proximity to the genes cluster for stravidins targeting a different step in the biotin biosynthesis pathway.
Anna Vignolle, Martin Zehl, Jaime Felipe Guerrero Garzón, Olha Schneider, Johannes Gafriller, Ulrike Grienke, Rasmus H. Kirkegaard, Sergey B. Zotchev   +7 more
wiley   +1 more source

Thiosulphate sulfurtransferase: Biological roles and therapeutic potential

Redox Biology
Mitochondria are central to eukaryotic cell function, driving energy production, intermediary metabolism, and cellular homeostasis. Dysregulation of mitochondrial function often results in oxidative stress, a hallmark of numerous diseases, underscoring the critical need for maintaining mitochondrial integrity.
Yang Luo, Shaden Melhem, Martin Feelisch, Laurent Chatre, Nicholas M. Morton, Amalia M. Dolga, Harry van Goor   +6 more
openaire   +3 more sources

Plant mercaptopyruvate sulfurtransferases [PDF]

European Journal of Biochemistry, 2000
Mercaptopyruvate sulfurtransferase (MST, EC 2.8.1.2) and thiosulfate sulfurtransferase (TST, rhodanese, EC 2.8.1.1) are evolutionarily related enzymes that catalyze the transfer of sulfur ions from mercaptopyruvate and thiosulfate, respectively, to cyanide ions.
T, Nakamura, Y, Yamaguchi, H, Sano
openaire   +2 more sources

The Preservation of Muscle Mitochondrial Machinery During Hypometabolic Hibernation in Scandinavian Brown Bears (Ursus arctos)

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Unlike humans, brown bears (Ursus arctos) uniquely preserve skeletal muscle mass and function during months of hibernation despite prolonged fasting and inactivity. We investigated how mitochondrial energetics respond in skeletal muscle to support this remarkable resilience.
Audrey Bergouignan, John Noone, Charlotte Brun, Laura Cussonneau, Alexandre Geffroy, Cecile Coudy‐Gandilhon, Isabelle Chery, Alina Lynn Evans, Jon Martin Arnemo, Jonas Kindberg, Guillemette Gauquelin‐Koch, Donal O'Gorman, Etienne Lefai, Fabrice Bertile   +13 more
wiley   +1 more source

Unraveling the role of thiosulfate sulfurtransferase in metabolic diseases

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2020
Thiosulfate sulfurtransferase (TST, EC 2.8.1.1), also known as Rhodanese, is a mitochondrial enzyme which catalyzes the transfer of sulfur in several molecular pathways. After its initial identification as a cyanide detoxification enzyme, it was found that its functions also include sulfur metabolism, modification of iron‑sulfur clusters and the ...
Paul D, Kruithof, Sergey, Lunev, Sheila P, Aguilar Lozano, Fernando, de Assis Batista, Zayana M, Al-Dahmani, Jaap A, Joles, Amalia M, Dolga, Matthew R, Groves, Harry, van Goor   +8 more
openaire   +2 more sources

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source