Results 31 to 40 of about 840 (125)
One Hundred Years of Sulfido Ligand in the Molybdenum Cofactor: New Perspectives
ChemBioChem, Volume 27, Issue 19, 14 October 2026.The terminal sulfido ligand in mononuclear molybdoenzymes has been appreciated for almost 125 years, with the characterization of Schardinger's enzyme in cow's milk, now known to be xanthine oxidase, that was isolated in 1902 in Vienna, Austria. The ligand is found in molybdoenzymes identified across all kingdoms of life.
Silke Leimkühler +2 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 18, 30 September 2026.Cardioprotective hormone relaxin‐2 showed relevant effects on rat skeletal muscle by altering proteins linked to muscle function, regeneration, differentiation, mitochondrial function, glucose metabolism, and structural integrity and organization. Specifically, relaxin‐2 reduced the expression of 95 proteins, increased 32, and elicited unique proteins ...
Xocas Vázquez‐Abuín +11 more
wiley +1 more source
Amino Acid Metabolism in Health and Disease
MedComm, Volume 7, Issue 9, September 2026.This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su +7 more
wiley +1 more source
Ergothioneine: Biosynthesis, Molecular Mechanisms, Physiological Function, and Role in Disease
MedComm, Volume 7, Issue 9, September 2026.Ergothioneine is a natural thione antioxidant with significant biomedical potential. By reducing oxidative stress, inflammation, mitochondrial dysfunction, and cellular injury, ergothioneine may support interventions for aging‐related disorders, neurodegeneration, metabolic diseases, and skin protection.
Guojuan Yi +6 more
wiley +1 more source
, 2018 International audienceSulfhydration of reactive cysteines in target proteins is now recognized as a major route by which H2S mediates signal transduction and regulates various cellular processes.
François Talfournier +11 more
core +1 more source
The Therapeutic Potential of H2S‐Releasing Platforms in Cardiovascular Applications
Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 8, August 2026.The Therapeutic Potential of H2S‐Releasing Platforms. ABSTRACT Once known as a toxic gas, hydrogen sulfide (H2S) is now making its way into many therapeutic applications. Similar to its other fellow endogenous gasotransmitters, nitric oxide and carbon monoxide, H2S is a small gas with a short half‐life, making it extremely capable of penetrating ...
Tia N. Shorter, Elizabeth J. Brisbois
wiley +1 more source
Rhodanese-fold sulfurtransferases : from mitochondrial H2S catalbolism to biocatalysis
, 2022 Les thioltransférases à domaine rhodanèse sont des enzymes ubiquitaires qui catalysent une réaction de transfert de soufre d’un substrat donneur vers un accepteur, via un mécanisme à deux étapes impliquant la formation d’un intermédiaire persulfure sur ...
Claudel, Anne-Lise
core
Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.To date, only three microorganisms have been functionally characterised for sulfur disproportionation. Our work identifies a fourth example and provides novel proteomic insights into its underlying pathways. These findings advance our understanding of microbial sulfur catabolism and highlight the ecological role of D.
Marilina Fernandez +8 more
wiley +1 more source
Enzymatic activity of the Arabidopsis sulfurtransferase resides in the C-terminal domain but is boosted by the N-terminal domain and the linker peptide in the full-length enzyme [PDF]
, 2005 Sulfurtransferases/rhodaneses are a group of enzymes widely distributed in plants, animals, and bacteria that catalyze the transfer of sulfur from a donor molecule to a thiophilic acceptor substrate.
Papenbrock, Jutta +2 more
core +1 more source
European Journal of Neuroscience, Volume 64, Issue 2, July 2026.miR‐124‐3p mimic reduced immobility in the Porsolt swim test in female mice. Proteomics revealed region‐specific changes in hippocampus, hypothalamus and PFC. Downregulation of immune and stress‐related proteins in hippocampus and hypothalamus. Upregulation of synaptic and metabolic proteins in the prefrontal cortex.
Maria A. Kuznetsova +6 more
wiley +1 more source