Results 41 to 50 of about 769 (137)

The Genetic Factors Controlling the Accumulation of Amylase/Trypsin Inhibitors (ATIs) in Barley for Enhancing Human Nutrition and Health

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
ATIs in cereal seeds link to celiac disease, asthma, and immune response. Here, we report the first study exploring genetic factors affecting ATI levels in barley. GWAS identified multiple QTNs influencing ATI accumulation with notable variation. Eight QTNs are associated with lower ATI levels; a key gene was identified.
Dalia Z. Alomari, Samar G. Thabet, Mashael D. Alqahtani, Matías Schierenbeck, Sarah Joestl, Sabrina Geisslitz, Katharina A. Scherf, Andreas Börner, Ahmad M. Alqudah   +8 more
wiley   +1 more source

Isolation and characterization of a prokaryotic sulfurtransferase.

Journal of Biological Chemistry, 1987
A sulfurtransferase has been purified to apparent homogeneity from the prokaryote Acinetobacter calcoaceticus lwoffi by conventional protein fractionation techniques. Steady-state kinetic studies of the enzyme revealed that its formal mechanism varies with the acceptor substrate employed. With inorganic thiosulfate as the sulfane sulfur-donor substrate
B A, Aird, R L, Heinrikson, J, Westley
openaire   +2 more sources

Structural studies on sulfurtransferase/phosphatase enzymes [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 2005
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Bordo, D., Spallarossa, A., Pagani, S., Larson, T., Bolognesi, M.   +4 more
openaire   +2 more sources

NRF2 signalling in cytoprotection and metabolism

British Journal of Pharmacology, Volume 183, Issue 1, Page 101-114, January 2026.
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami, Yusuke Kusano, Keito Okazaki, Takaaki Akaike, Hozumi Motohashi   +4 more
wiley   +1 more source

Supersulfide biology and translational medicine for disease control

British Journal of Pharmacology, Volume 183, Issue 1, Page 115-130, January 2026.
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu, Tomohiro Sawa, Motohiro Nishida, Fan‐Yan Wei, Hozumi Motohashi, Takaaki Akaike   +5 more
wiley   +1 more source

Sorghum Poisoning in Livestock: Mechanisms, Risks, and Sustainable Mitigation Strategies

International Journal of Agronomy, Volume 2026, Issue 1, 2026.
Sorghum (Sorghum bicolor L. Moench) is a drought‐tolerant crop grown in both arid and semiarid regions and serves as both food and fodder. Under environmental stresses, sorghum accumulates cyanogenic glucosides, especially dhurrin. Through ingestion, dhurrin is hydrolyzed into a toxic element called hydrogen cyanide (HCN).
Mahmud Sindid Ikram, Sumiya Akter Moni, Othmane Merah   +2 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Dietary methionine depletion and hydrogen sulfide‐producing genes in perivascular adipose tissue of male Wistar rats

Physiological Reports, Volume 13, Issue 24, December 2025.
Abstract Perivascular adipose tissue (PVAT) regulates vascular tone, and high‐fat diets reportedly lead to the loss of its anti‐contractile properties. Methionine restriction recapitulates many caloric restriction metabolic effects and increases liver expression of activating transcription factor 4 (ATF4) and downstream targets with anti‐contractile ...
Adam Corken, Davis Lee, Elizabeth C. Wahl, James D. Sikes, Keshari M. Thakali   +4 more
wiley   +1 more source

Catalytic Site Cysteines of Thiol Enzyme: Sulfurtransferases [PDF]

Journal of Amino Acids, 2011
Thiol enzymes have single- or double-catalytic site cysteine residues and are redox active. Oxidoreductases and isomerases contain double-catalytic site cysteine residues, which are oxidized to a disulfide via a sulfenyl intermediate and reduced to a thiol or a thiolate. The redox changes of these enzymes are involved in their catalytic processes.
openaire   +2 more sources

Rhodanese-Fold Containing Proteins in Humans: Not Just Key Players in Sulfur Trafficking. [PDF]

Antioxidants (Basel), 2023
Alsohaibani R, Claudel AL, Perchat-Varlet R, Boutserin S, Talfournier F, Boschi-Muller S, Selles B.   +6 more
europepmc   +1 more source