Results 41 to 50 of about 1,145 (168)

Identification of sulfurtransferase enzymes in Azotobacter vinelandii [PDF]

FEBS Letters, 1991
Rhodanese and 3‐mercaptopyruvate sulphurtransferase have been identified in A. vinelandii. Two distinct active fractions of the two sulphurtransferases were obtained after FPLC ion‐exchange chromatography of material partially purified from crude extracts. Rhodanese has been purified to homogeneity, and it consists of one polypeptide chain of M r ca 25
Pagani, S., Franchi, E., Colnaghi, R., Kennedy, C.   +3 more
openaire   +2 more sources

The Preservation of Muscle Mitochondrial Machinery During Hypometabolic Hibernation in Scandinavian Brown Bears (Ursus arctos)

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Unlike humans, brown bears (Ursus arctos) uniquely preserve skeletal muscle mass and function during months of hibernation despite prolonged fasting and inactivity. We investigated how mitochondrial energetics respond in skeletal muscle to support this remarkable resilience.
Audrey Bergouignan, John Noone, Charlotte Brun, Laura Cussonneau, Alexandre Geffroy, Cecile Coudy‐Gandilhon, Isabelle Chery, Alina Lynn Evans, Jon Martin Arnemo, Jonas Kindberg, Guillemette Gauquelin‐Koch, Donal O'Gorman, Etienne Lefai, Fabrice Bertile   +13 more
wiley   +1 more source

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

Insight into the sulfur metabolism of Desulfurella amilsii by differential proteomics [PDF]

, 2018
Many questions regarding proteins involved in microbial sulfur metabolism remain unsolved. For sulfur respiration at low pH, the terminal electron acceptor is still unclear.
Aussignargues, Berg, Bielow, Bill, Blumentals, Boulegue, Boyd, Chandramouli, Cline, Cox, Cox, Cox, Dahl, Dahl, Finster, Finster, Florentino, Florentino, Florentino, Florentino, Franz, Franz, Friedrich, Gebhardt, Giuliani, Grein, Hardisty, Hedderich, Hubner, Hugler, Junier, Klausen, Klimmek, Klimmek, Laska, Lin, Liu, Lu, Ma, Mall, Mikami, O'Toole, Ohmura, Pereira, Rabus, Rappsilber, Rawlings, Rohwerder, Santos, Schauder, Schmitz, Steudel, Stoffels, Surkov, Sánchez-Andrea, Tang, Vizcaíno, Wang   +57 more
core   +1 more source

The Genetic Factors Controlling the Accumulation of Amylase/Trypsin Inhibitors (ATIs) in Barley for Enhancing Human Nutrition and Health

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
ATIs in cereal seeds link to celiac disease, asthma, and immune response. Here, we report the first study exploring genetic factors affecting ATI levels in barley. GWAS identified multiple QTNs influencing ATI accumulation with notable variation. Eight QTNs are associated with lower ATI levels; a key gene was identified.
Dalia Z. Alomari, Samar G. Thabet, Mashael D. Alqahtani, Matías Schierenbeck, Sarah Joestl, Sabrina Geisslitz, Katharina A. Scherf, Andreas Börner, Ahmad M. Alqudah   +8 more
wiley   +1 more source

Atomic sulfur : an element for adaptation to an oxidative environment [PDF]

, 2017
During the period of rising oxygen concentration in the Earth’s atmosphere (Figure 1), sulfur atoms were incorporated into proteins as redox-active cysteine residues [1] and antioxidant molecules such as thioredoxin, glutathione, and glutaredoxin ...
Nagahara, Noryuki, Wróbel, Maria
core   +2 more sources

Thiosulphate sulfurtransferase: Biological roles and therapeutic potential

Redox Biology
Mitochondria are central to eukaryotic cell function, driving energy production, intermediary metabolism, and cellular homeostasis. Dysregulation of mitochondrial function often results in oxidative stress, a hallmark of numerous diseases, underscoring the critical need for maintaining mitochondrial integrity.
Yang Luo, Shaden Melhem, Martin Feelisch, Laurent Chatre, Nicholas M. Morton, Amalia M. Dolga, Harry van Goor   +6 more
openaire   +3 more sources

NRF2 signalling in cytoprotection and metabolism

British Journal of Pharmacology, Volume 183, Issue 1, Page 101-114, January 2026.
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami, Yusuke Kusano, Keito Okazaki, Takaaki Akaike, Hozumi Motohashi   +4 more
wiley   +1 more source

Supersulfide biology and translational medicine for disease control

British Journal of Pharmacology, Volume 183, Issue 1, Page 115-130, January 2026.
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu, Tomohiro Sawa, Motohiro Nishida, Fan‐Yan Wei, Hozumi Motohashi, Takaaki Akaike   +5 more
wiley   +1 more source

Repetitive and Non-Repetitive DNA Sequences and a Speculation on the Origins of Evolutionary Novelty [PDF]

, 1971
Recent experimental information on DNA sequence repetition is reviewed, and the significance of both repetitive and non-repetitive sequence considered.
Britten, Roy J., Davidson, Eric H.
core   +1 more source