Results 61 to 70 of about 1,145 (168)

3‐Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics [PDF]

British Journal of Pharmacology, 2019
Background and PurposeDuring angiogenesis, quiescent endothelial cells (ECs) are activated by various stimuli to form new blood vessels from pre‐existing ones in physiological and pathological conditions. Many research groups have shown that hydrogen sulfide (H2S), the newest member of the gasotransmitter family, acts as a proangiogenic factor. To date,
Armita Abdollahi Govar, Gábor Törő, Peter Szaniszlo, Athanasia Pavlidou, Sofia‐Iris Bibli, Ketan Thanki, Vicente A. Resto, Celia Chao, Mark R. Hellmich, Csaba Szabo, Andreas Papapetropoulos, Katalin Módis   +11 more
openaire   +4 more sources

Cysteine Signalling in Plant Pathogen Response

Plant, Cell &Environment, Volume 48, Issue 10, Page 7107-7122, October 2025.
ABSTRACT The amino acid cysteine is the precursor for a wide range of sulfur‐containing functional molecules in plants, including enzyme cofactors and defence compounds. Due to its redox active thiol group cysteine is highly reactive. Synthesis and degradation pathways are present in several subcellular compartments to adjust the intracellular cysteine
Jannis Moormann, Björn Heinemann, Cecile Angermann, Anna Koprivova, Ute Armbruster, Stanislav Kopriva, Tatjana M. Hildebrandt   +6 more
wiley   +1 more source

Catalytic Site Cysteines of Thiol Enzyme: Sulfurtransferases [PDF]

Journal of Amino Acids, 2011
Thiol enzymes have single- or double-catalytic site cysteine residues and are redox active. Oxidoreductases and isomerases contain double-catalytic site cysteine residues, which are oxidized to a disulfide via a sulfenyl intermediate and reduced to a thiol or a thiolate. The redox changes of these enzymes are involved in their catalytic processes.
openaire   +2 more sources

d‐amino acids: new functional insights

The FEBS Journal, Volume 292, Issue 17, Page 4395-4417, September 2025.
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni, Natasa Kustrimovic, Luciano Piubelli, Elena Rosini, Valentina Rabattoni, Silvia Sacchi   +5 more
wiley   +1 more source

Proteomic Analysis Infers Optimized ATP‐Production in Guard Cell Mitochondria

Physiologia Plantarum, Volume 177, Issue 5, September/October 2025.
ABSTRACT Guard cells are highly specialised leaf cells which regulate leaf transpiration and carbon fixation. As such, they are instrumental in balancing water use efficiency and photosynthetic activity. This unique function of guard cells requires them to quickly accumulate solutes for ATP‐dependent stomatal opening, but how this affects mitochondrial
Noah Ditz, Markus Niehaus, Nieves Medina Escobar, Marco Herde, Holger Eubel   +4 more
wiley   +1 more source

Hydrogen Sulfide Protects Erectile Function Through Stimulation of Antioxidant Defense in the Corpus Cavernosum: Insights From SG1002 Administration and Cystathionine γ‐Lyase Knockout

The FASEB Journal, Volume 39, Issue 15, 15 August 2025.
Chronic consumption of a western diet suppressed corpus cavernosum cystathionine γ‐lyase (CSE) protein content and H2S production and was associated with elevated penile reactive oxygen species (ROS) levels and impaired erectile function. CSE knockout mice demonstrate impaired erectile function, elevated penile ROS levels, and suppressed corpus ...
Tooyib A. Azeez, Paige R. Rhein, Clifford J. Pierre, Colin M. Ihrig, Justin D. La Favor   +4 more
wiley   +1 more source

Identification of protein partners of the Azotobacter vinelandii rhodanese-like protein RhdA by pull-down approaches [PDF]

Rhodaneses (TST; EC 2.8.1.1) catalyze in vitro the transfer of sulfane sulfur from thiosulfate to cyanide with the concomitant formation of thiocyanate.
Forlani, Fabio, Guerrieri, Nicoletta, Remelli, William, Seregni, Morena   +3 more
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Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase

Biochemical Pharmacology, 2020
Hydrogen sulfide (H2S) is a physiological mediator that regulates cardiovascular homeostasis. Three major enzymes contribute to the generation of endogenously produced H2S, namely cystathionine γ-lyase (CSE), cystathionine β-synthase (CBS) and 3-mercaptopyruvate sulfurtransferase (3-MST).
Maria Peleli, Sofia-Iris Bibli, Zhen Li, Athanasia Chatzianastasiou, Aimilia Varela, Antonia Katsouda, Sven Zukunft, Mariarosaria Bucci, Valentina Vellecco, Constantinos H Davos, Noriyuki Nagahara, Giuseppe Cirino, Ingrid Fleming, David J Lefer, Andreas Papapetropoulos   +14 more
openaire   +4 more sources

Investigating the Catalytic and the Metabolic Role of the Thiol Dioxygenase and a Sulfurtransferase in the mdo Operon from Pseudomonas aeruginosa [PDF]

, 2019
Mammalian cysteine dioxygenase (CDO) is a mononuclear iron containing enzyme that belongs to the cupin superfamily. CDO catalyzes the oxidation of cysteine to cysteine sulfinic acid.
Laura, Tombrello
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Alternative sulfur acquisition pathways in Neisseria gonorrhoeae [PDF]

, 2021
Neisseria gonorrhoeae is an obligate human pathogen responsible for the sexually transmitted infection, gonorrhoea. Its success as a pathogen is partly due to robust defence mechanisms that provide protection against oxidative stress encountered during ...
van Niekerk, Stacy Lyn
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