Results 61 to 70 of about 2,505 (224)
Physiological Reports, Volume 13, Issue 24, December 2025.Abstract Perivascular adipose tissue (PVAT) regulates vascular tone, and high‐fat diets reportedly lead to the loss of its anti‐contractile properties. Methionine restriction recapitulates many caloric restriction metabolic effects and increases liver expression of activating transcription factor 4 (ATF4) and downstream targets with anti‐contractile ...
Adam Corken +4 more
wiley +1 more source
Thiosulphate sulfurtransferase: Biological roles and therapeutic potential
Redox BiologyMitochondria are central to eukaryotic cell function, driving energy production, intermediary metabolism, and cellular homeostasis. Dysregulation of mitochondrial function often results in oxidative stress, a hallmark of numerous diseases, underscoring the critical need for maintaining mitochondrial integrity.
Yang Luo +6 more
openaire +3 more sources
Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function
Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.ABSTRACT Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, including endothelial cells, produce cyanide endogenously, where it can modulate mitochondrial bioenergetics ...
Elif Alan‐Albayrak, Ulf Simonsen
wiley +1 more source
Atomic sulfur : an element for adaptation to an oxidative environment [PDF]
, 2017 During the period of rising oxygen concentration in the Earth’s atmosphere (Figure 1), sulfur atoms were incorporated into proteins as redox-active cysteine residues [1] and antioxidant molecules such as thioredoxin, glutathione, and glutaredoxin ...
Nagahara, Noryuki, Wróbel, Maria
core +2 more sources
Microcirculation, Volume 32, Issue 7, October 2025.ABSTRACT Endothelial cells (ECs) express an array of integral membrane proteins, including ion channels and transporters that contribute to blood flow regulation and cell–cell communication. Many of these membrane proteins are regulated by plasma membrane cholesterol content.
Jacob R. Anderson +3 more
wiley +1 more source
The effect of lipoic acid on cyanate toxicity in different structures of the rat brain [PDF]
, 2013 Cyanate is formed mostly during nonenzymatic urea biodegradation. Its active form isocyanate reacts with protein –NH(2) and –SH groups, which changes their structure and function. The present studies aimed to investigate the effect of cyanate on activity
Bilska-Wilkosz, Anna +3 more
core +1 more source
Cysteine Signalling in Plant Pathogen Response
Plant, Cell &Environment, Volume 48, Issue 10, Page 7107-7122, October 2025.ABSTRACT The amino acid cysteine is the precursor for a wide range of sulfur‐containing functional molecules in plants, including enzyme cofactors and defence compounds. Due to its redox active thiol group cysteine is highly reactive. Synthesis and degradation pathways are present in several subcellular compartments to adjust the intracellular cysteine
Jannis Moormann +6 more
wiley +1 more source
Characterization of a sulfurtransferase from Arabidopsis thaliana [PDF]
European Journal of Biochemistry, 2000 A database search for similarities between sequenced parts of the Arabidopsis thaliana genome with known sulfurtransferase sequences from Escherichia coli and mammals was undertaken to obtain information about plant sulfurtransferase‐like proteins. One gene and several homologous EST clones were identified.
J, Papenbrock, A, Schmidt
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d‐amino acids: new functional insights
The FEBS Journal, Volume 292, Issue 17, Page 4395-4417, September 2025.This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni +5 more
wiley +1 more source
Proteomic Analysis Infers Optimized ATP‐Production in Guard Cell Mitochondria
Physiologia Plantarum, Volume 177, Issue 5, September/October 2025.ABSTRACT Guard cells are highly specialised leaf cells which regulate leaf transpiration and carbon fixation. As such, they are instrumental in balancing water use efficiency and photosynthetic activity. This unique function of guard cells requires them to quickly accumulate solutes for ATP‐dependent stomatal opening, but how this affects mitochondrial
Noah Ditz +4 more
wiley +1 more source