Results 61 to 70 of about 2,387 (211)
Alternative sulfur acquisition pathways in Neisseria gonorrhoeae [PDF]
Neisseria gonorrhoeae is an obligate human pathogen responsible for the sexually transmitted infection, gonorrhoea. Its success as a pathogen is partly due to robust defence mechanisms that provide protection against oxidative stress encountered during ...
van Niekerk, Stacy Lyn
core
Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase
Hydrogen sulfide (H2S) is a physiological mediator that regulates cardiovascular homeostasis. Three major enzymes contribute to the generation of endogenously produced H2S, namely cystathionine γ-lyase (CSE), cystathionine β-synthase (CBS) and 3-mercaptopyruvate sulfurtransferase (3-MST).
Antonia Katsouda+15 more
openaire +3 more sources
Abstract figure legend Sodium thiosulfate (STS) rescues the pronephros phenotype of pdx1 morphants through compensatory upregulation of nitric oxide (NO) metabolism. Zebrafish larvae injected with a control morpholino show the typical pronephros structure at 48 h post‐fertilization (hpf) with and without STS treatment.
Hannes Ott+6 more
wiley +1 more source
The glial Gomori-positive material is sulfane sulpfur. [PDF]
The Gomori-positive glia are periventricular astrocytes with abundant cytoplasmic granular material, predominantly occupying a periventricular site in the brain.
Góralska, Marta+3 more
core +2 more sources
Supersulfides: A Promising Therapeutic Approach for Autoinflammatory Diseases
ABSTRACT Supersulfides are molecular species characterized by catenated sulfur moieties, including low‐molecular‐weight and protein‐bound supersulfides. Emerging evidence suggests that these molecules, abundantly present in diverse organisms, play essential roles far beyond their chemical properties, such as functions in energy metabolism, protein ...
Tianli Zhang+4 more
wiley +1 more source
In this study, an innovative hydrogen sulfide (H2S)‐activated near‐infrared fluorogenic probe (hCy‐DNP) was developed and its H2S‐specific responses were systematically investigated in vivo and in vitro. With efficient H2S recognition capability, hCy‐DNP successfully achieved high‐precision fluorescent targeted sensing in the phased progression of ...
Weier Liang+7 more
wiley +1 more source
Genome sequence of Desulfurella amilsii strain TR1 and comparative genomics of Desulfurellaceae family [PDF]
The acidotolerant sulfur reducer Desulfurella amilsii was isolated from sediments of Tinto river, an extremely acidic environment. Its ability to grow in a broad range of pH and to tolerate certain heavy metals offers potential for metal recovery ...
Ahemad+63 more
core +3 more sources
Advances in Detection Methods for A‐to‐I RNA Editing
Caption: Early identification of A‐to‐I RNA editing sites was achieved through Sanger sequencing, with the introduction of next‐generation sequencing (NGS) enabling transcriptome‐wide analyses. In recent years, detection approaches have expanded beyond sequencing‐based strategies to include chemically assisted and enzyme‐assisted methods, which offer ...
Yuxi Yang, Masayuki Sakurai
wiley +1 more source
Structural and Mechanistic Insights into Hemoglobincatalyzed Hydrogen Sulfide Oxidation and the Fate of Polysulfide Products [PDF]
Hydrogen sulfide is a cardioprotective signaling molecule but is toxic at elevated concentrations. Red blood cells can synthesize H2S but, lacking organelles, cannot dispose of H2S via the mitochondrial sulfide oxidation pathway.
An, Sojin+5 more
core +6 more sources
H2S Donor SPRC Ameliorates Ischemic Stroke by Upregulating CD24
CD24 may be a potential innovative target of ischemic stroke for alleviating neuroinflammation via NF‐κB pathway and Src pathway. The treatment of SPRC on ischemic stroke is associated with CD24 via CBS/H2S pathway. ABSTRACT Background Ischemic stroke is well‐known for its high mortality and morbidity, but its treatment remains to be explored due to ...
Chenye Wang+8 more
wiley +1 more source