Results 61 to 70 of about 71,461 (340)
We investigate the effective radiative forcing (ERF) of anthropogenic aerosols using simulations from seven Earth System Models participating in the Coupled Model Intercomparison Project Phase 6 (CMIP6).
Alkiviadis Kalisoras+5 more
doaj +1 more source
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Feasibility study of sulfates as oxygen carriers for chemical looping processes [PDF]
The operational feasibility temperature range of chemical looping combustion (CLC) and chemical looping reforming (CLR) of the fuels methane, propane, iso-octane and ethanol was explored using the common ...
Ganesh Kale
doaj +1 more source
Rejoinder: "A significance test for the lasso" [PDF]
Rejoinder of "A significance test for the lasso" by Richard Lockhart, Jonathan Taylor, Ryan J. Tibshirani, Robert Tibshirani [arXiv:1301.7161].Comment: Published in at http://dx.doi.org/10.1214/14-AOS1175REJ the Annals of Statistics (http://www.imstat ...
Lockhart, Richard+3 more
core +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
In the blaze and glory of the heraldry of new remedies and elegant pharmacy, physicians are apt to forget, or at least overlook, some of the old, tried and true preparations. In diverting attention to one of these, no intention is made to cast any slur on, or to detract from, the value and usefulness of others.
openaire +3 more sources
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
In this work a fast and environmentally friendly method for the extraction and quantification of soluble sulphates in red clay using microwave assisted extraction (MAE) and determination by turbidimetry was developed and validated.
V. I. Cáceres+2 more
doaj +1 more source
CALCIUM SULPHATE IN AMMONIUM SULPHATE SOLUTION1. [PDF]
n ...
openaire +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source