Results 61 to 70 of about 71,461 (340)

Estimating the Effective Radiative Forcing of Anthropogenic Aerosols with the Use of CMIP6 Earth System Models

open access: yesEnvironmental Sciences Proceedings, 2023
We investigate the effective radiative forcing (ERF) of anthropogenic aerosols using simulations from seven Earth System Models participating in the Coupled Model Intercomparison Project Phase 6 (CMIP6).
Alkiviadis Kalisoras   +5 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Feasibility study of sulfates as oxygen carriers for chemical looping processes [PDF]

open access: yesQScience Connect, 2012
The operational feasibility temperature range of chemical looping combustion (CLC) and chemical looping reforming (CLR) of the fuels methane, propane, iso-octane and ethanol was explored using the common ...
Ganesh Kale
doaj   +1 more source

Rejoinder: "A significance test for the lasso" [PDF]

open access: yes, 2014
Rejoinder of "A significance test for the lasso" by Richard Lockhart, Jonathan Taylor, Ryan J. Tibshirani, Robert Tibshirani [arXiv:1301.7161].Comment: Published in at http://dx.doi.org/10.1214/14-AOS1175REJ the Annals of Statistics (http://www.imstat ...
Lockhart, Richard   +3 more
core   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

SULPHATE OF MAGNESIA.

open access: yesJAMA: The Journal of the American Medical Association, 1899
In the blaze and glory of the heraldry of new remedies and elegant pharmacy, physicians are apt to forget, or at least overlook, some of the old, tried and true preparations. In diverting attention to one of these, no intention is made to cast any slur on, or to detract from, the value and usefulness of others.
openaire   +3 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Development and validation of an analytical method for the extraction and quantification of soluble sulfates in red clay

open access: yesCerâmica, 2015
In this work a fast and environmentally friendly method for the extraction and quantification of soluble sulphates in red clay using microwave assisted extraction (MAE) and determination by turbidimetry was developed and validated.
V. I. Cáceres   +2 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

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