Results 121 to 130 of about 6,612,775 (264)

Childhood Hodgkin Lymphoma (hl): single centre experience from eastern India

Pediatric Hematology Oncology Journal, 2022
ADITI SHARMA, SAROJ PANDA, NIRMALYA PRADHAN, MRUTYUNJAY DASH   +3 more
doaj   +1 more source

Two Uncommon Cases of Pediatric Transethmoidal–Transnasal Encephaloceles with a Review of Literature

Indian Journal of Neurosurgery
Encephaloceles are defined as the herniation of brain matter beyond the confines of the skull bone through a defect on the cranium or face. The encephaloceles are classified into different categories as per onset as congenital or traumatic, as per ...
Abhijit Acharya, Satya Bhusan Senapati, Souvagya Panigrahi, Rama Chandra Deo, A. K. Mahapatra   +4 more
doaj   +1 more source

Power sums of digital sums

Journal of Number Theory, 1986
Let \(e_ r(n)\), \(r\geq 0\), be the dyadic digits of the integer n. Set \(s(n)=\sum_{r}e_ r(n)\), and \(S_ d(N)=\sum_{n\leq N}s^ d(n)\). The author obtains asymptotic formulas, with error terms, for \(S_ d(N)\) as \(N\to +\infty\).
openaire   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Sums of Kloosterman sums

Inventiones Mathematicae, 1983
Sarnak, P., Goldfeld, D.
openaire   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

PD-L1 expression and its significance in advanced NSCLC: real-world experience from a tertiary care center

Journal of the Egyptian National Cancer Institute
Background Targeted therapies against programmed death ligand-1 (PD-L1) in non-small cell lung cancer (NSCLC) have revolutionized the management in recent years. There is paucity of data on the significance of PD-L1 expression in NSCLC from India.
Sindhu Kilaru, Soumya Surath Panda, Lalatendu Moharana, Debahuti Mohapatra, Satya Sundar G. Mohapatra, Adyakinkar Panda, Spoorthy Kolluri, Suma Devaraj, Ghanashyam Biswas   +8 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source