Results 61 to 70 of about 163,760 (356)

Nonparametric estimation in random sum models

open access: yesStatistica, 2013
Let X1,X2,…,XN be independent, identically distributed, non-negative, integervalued random variables and let N be a non-negative, integer-valued random variable independent of X1,X2,…,XN .
Hassan S. Bakouch, Thomas A. Severini
doaj   +1 more source

Some Useful Integral Representations for Information-Theoretic Analyses

open access: yesEntropy, 2020
This work is an extension of our earlier article, where a well-known integral representation of the logarithmic function was explored and was accompanied with demonstrations of its usefulness in obtaining compact, easily-calculable, exact formulas for ...
Neri Merhav, Igal Sason
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

A Geometric Derivation of the Irwin-Hall Distribution

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2017
The Irwin-Hall distribution is the distribution of the sum of a finite number of independent identically distributed uniform random variables on the unit interval.
James E. Marengo   +2 more
doaj   +1 more source

The Convergence of the Sums of Independent Random Variables Under the Sub-linear Expectations [PDF]

open access: yes, 2019
Let { X n ; n ≥ 1} be a sequence of independent random variables on a probability space (Ω ,F ,P) and $${S_n} = \sum\nolimits_{k = 1}^n {{X_k}} $$ . It is well-known that the almost sure convergence, the convergence in probability and the convergence in ...
Li-Xin Zhang
semanticscholar   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Representations for Integral Functionals of Kernel Density Estimators

open access: yesAustrian Journal of Statistics, 2016
We establish a representation as a sum of independent random variables, plus a remainder term, for estimators of integral functionals of the density function, which have a certain simple structure.
David M. Mason
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Unimodality of the probability distribution of the extensive functional of samples of a random sequence

open access: yesСовременная математика: Фундаментальные направления
We establish a criterion for the unimodality of the probability distribution of a functional that is represented by the sum of a set of independent identically distributed random nonnegative variables \({\tilde x}_k\) with a random number of terms ...
Yu. P. Virchenko, A. M. Tevolde
doaj   +1 more source

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