Results 71 to 80 of about 8,529,264 (233)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

On generalized absolute summability factors for a triangular matrix [PDF]

open access: yes, 2009
In this paper, we establish a summability factor theorem for summability {divides}A, ?{divides}k as defined in (2). This paper is an extension of the main result of Savaş and Rhoades [Savaş E, Rhoades B.
Savaş, Ekrem
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

On |\overline𝑁,𝑝_{𝑛}|_{𝑘} summability factors

open access: yes, 1985
In this paper a theorem on | N ¯ , p n | k ...
Hüseyin Bor
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

On the absolute Cesàro summability factors

open access: yesJournal of Numerical Analysis and Approximation Theory, 1991
Not available.
Hüseyin Bor
doaj   +2 more sources

Extension of Mazhar’s theorem on summability factors

open access: yesKuwait Journal of Science, 2015
By  (X; Y ) we denote the set of all sequences such thatPa nnis summable  X wheneverPa n is summable Y , where X and Y are sum-mability methods. In this paper we characterize the set  (jC; jk ;N; p n)  fork >  1; > 􀀀1 and arbitrary positive ...
MEHMET ALI SARIGOL
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

A new application of almost increasing sequences

open access: yesAnnales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2019
In this paper, a known result dealing with |N, pn|k summability of infinite series has been generalized to the φ-|N, pn;δ|k infinite series by using an almost increasing sequence.
Ahmet Karakaş
doaj  

Home - About - Disclaimer - Privacy