Results 101 to 110 of about 46,190 (264)

Luminescent Donor‐Acceptor Radical With Propeller Chirality: Bright and Photostable Red Circularly Polarized Luminescence and Whispering Gallery Mode Resonance

Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.
A series of donor‐attached brominated chiral luminescent radicals (CzTTBrM, 2CzTTBrM, and 3CzTTBrM) was synthesized, showing red to near‐infrared (NIR) circularly polarized luminescence (CPL) with exceptionally high PLQY of up to 76% and markedly enhanced CPL brightness (BCPL). Doping into polystyrene microspheres further yields whispering gallery mode
Kazuhiro Nakamura, Kenshiro Matsuda, Kosuke Anraku, Keiko Yamaoka, Taisuke Matsumoto, Fumitaka Ishiwari, Takeaki Zaima, Wataru Ota, Emiko Fujiwara, Tohru Sato, Yoshitaka Inoue, Soh Kushida, Yohei Yamamoto, Takuya Hosokai, Ken Albrecht   +14 more
wiley   +2 more sources

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri, Amornthep Kingkaw, Nawarus Prapaiwan, Rangsima Sujittosakul, Nichapat Iamkaewprasert, Jiraschaya Piputwat, Puetta Isama‐al, Thanutchanok Munkongdee, Thanapon Chotikaprakal, Petchpailin Yanyongsirikarn, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Parichart Tesena   +13 more
wiley   +1 more source

Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells

, 2020
Post-translational modification by SUMO is a key regulator of cell identity. In mouse embryonic fibroblasts (MEFs), SUMO impedes reprogramming to pluripotency, while in embryonic stem cells (ESCs), it represses the emergence of totipotent-like cells ...
Hendriks, Ivo, Andrieux, Alexandra, Theurillat, Ilan, Dejean, Anne, Hendriks, Ivo A., Nielsen, Michael, Cossec, Jack-Christophe, Nielsen, Michael L.   +7 more
core   +1 more source

The potential role of As-sumo-1 in the embryonic diapause process and early embryo development of Artemia sinica.

PLoS ONE, 2014
During embryonic development of Artemia sinica, environmental stresses induce the embryo diapause phenomenon, required to resist apoptosis and regulate cell cycle activity.
Bing Chu, Feng Yao, Cheng Cheng, Yang Wu, Yanli Mei, Xuejie Li, Yan Liu, Peisheng Wang, Lin Hou, Xiangyang Zou   +9 more
doaj   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Role of SUMO-1 modification in transcriptional activation

, 2012
In unstimulated cells, the transcription factor NF-κB is held in the cytoplasm in an inactive state by IκB inhibitor proteins. Activation of NF--KB is mediated by signal induced degradation of IκBα via the ubiquitin proteasome-dependent pathway ...
Pinto Desterro, Maria Joana
core  

The SUMO hub

, 2022
The SUMO interaction hub involves SUMO readers and their SUMO substrate. It is a reliable platform for 1) investigating the SUMO system 2) detecting novel SUMO readers 3) detecting novel SUMO ...
Urbaniak, Konstancja, Division of Cancer Sciences   +1 more
core   +1 more source

Deep Reinforcement Learning Approach for Traffic Light Control and Transit Priority

Future Transportation
This study investigates the use of deep reinforcement learning techniques to improve traffic signal control systems through the integration of deep learning and reinforcement learning approaches.
Saeed Mansouryar, Chiara Colombaroni, Natalia Isaenko, Gaetano Fusco   +3 more
doaj   +1 more source

Mechanism of Adenovirus E4-ORF3-Mediated SUMO Modifications

mBio, 2019
Regulation of a variety of different cellular processes, including posttranslational modifications, is critical for the ability of many viruses to replicate efficiently within host cells.
Sook-Young Sohn, Patrick Hearing
doaj   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source