Results 81 to 90 of about 299,473 (288)

Experimental Characterization of Routing Protocols in Urban Vehicular Communication

open access: yesTransport and Telecommunication, 2019
Vehicular communication is a cynosure in automotive industry these days. V2V communication is one of the types of vehicular communication which render lane change warning, emergency vehicle alert, intersection alert, congestion alert, payment at tolls ...
Punia Divya, Kumar Rajender
doaj   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda   +5 more
wiley   +1 more source

SUMO and cellular adaptive mechanisms

open access: yesExperimental and Molecular Medicine, 2020
The ubiquitin family member SUMO is a covalent regulator of proteins that functions in response to various stresses, and defects in SUMO-protein conjugation or deconjugation have been implicated in multiple diseases.
Hong-Yeoul Ryu, S. Ahn, M. Hochstrasser
semanticscholar   +1 more source

Strong Nonradiative Recombination Induced by Pronounced Lone‐Pair Electron Expression Following Deprotonation in Aziridinium Lead Iodide Perovskites

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The transition from linear to cyclic organic cations promotes deprotonation and activates VH(N) defects with pronounced lone‐pair electron activity, thereby inducing severe local distortions and highly efficient nonradiative recombination centers. This work unveils a direct structure–defect–performance correlation and proposes design strategies for the
Qingshan Bao   +5 more
wiley   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

open access: yesInterdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu   +6 more
wiley   +1 more source

Domain Modeling in the Context of Ontology

open access: yesFoundations of Computing and Decision Sciences, 2015
The domain knowledge represented by ontology should be widely used in the design process of information system. The aim of the paper is to outline a systematic approach of developing a CIM model (domain model, precisely) on the basis of a selected domain
Dubielewicz Iwona   +3 more
doaj   +1 more source

A Method for SUMO Modification of Proteins in vitro

open access: yesBio-Protocol, 2018
The Small Ubiquitin-related Modifier (SUMO) is a protein that is post-translationally added to and reversibly removed from other proteins in eukaryotic cells.
Christine Lee   +3 more
doaj   +1 more source

Sumo

open access: yes, 2011
[ES] Definición del término Sumo en el diccionario Dicter. [EN] Definition of the word Sumo in the dictionary Dicter.
openaire   +3 more sources

SUMO Wrestling with Specificity [PDF]

open access: yesStructure, 2002
A new structure reveals how substrates are recognized for conjugation to the ubiquitin-like protein SUMO, a posttranslational modification that functions in activation of transcription factors, nuclear import, and cell division.
VanDemark, Andrew P, Hill, Christopher P
openaire   +2 more sources

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

open access: yesInterdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu   +6 more
wiley   +1 more source

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