Results 61 to 70 of about 299,473 (288)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Symbolic macromodeling of parameterized S-parameter frequency responses [PDF]
, 2010 This paper presents an evolutionary algorithm for symbolic macromodeling of parameterized frequency responses. The method does not require an a priori specification of the multivariate functional form or complexity of the model.
Deschrijver, Dirk, Dhaene, Tom
core +2 more sources
Cell Reports, 2020 Summary Post-translational modification by SUMO is a key regulator of cell identity. In mouse embryonic fibroblasts (MEFs), SUMO impedes reprogramming to pluripotency, while in embryonic stem cells (ESCs), it represses the emergence of totipotent-like ...
Ilan Theurillat +5 more
semanticscholar +1 more source
Spin‐Split Edge States in Metal‐Supported Graphene Nanoislands Obtained by CVD
Advanced Materials, EarlyView.Combining STM measurements and ab‐initio calculations, we show that zig‐zag edges in graphene nanoislands grown on Ni(111) by CVD retrieve their spin‐polarized edge states after intercalation of a few monolayers of Au. ABSTRACT Spin‐split states localized on zigzag edges have been predicted for different free‐standing graphene nanostructures.
Michele Gastaldo +6 more
wiley +1 more source
sumo: Command-line tools for plotting and analysis of periodic *ab initio* calculations
Journal of Open Source Software, 2018 License Authors of papers retain copyright and release the work under a Creative Commons Attribution 4.0 International License (CC-BY). Ab initio electronic structure modelling is capable of providing an insight into the fundamental properties of solid ...
A. Ganose, A. Jackson, D. Scanlon
semanticscholar +1 more source
Advanced Science, EarlyView.ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch +4 more
wiley +1 more source
Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation. [PDF]
PLoS ONE, 2009 SUMO is a protein modifier that is vital for multicellular development. Here we present the first system-wide analysis, combining multiple approaches, to correlate the sumoylated proteome (SUMO-ome) in a multicellular organism with the developmental ...
Minghua Nie +3 more
doaj +1 more source
A Photo-Crosslinking Approach to Identify Class II SUMO-1 Binders
Frontiers in Chemistry, 2022 The small ubiquitin-like modifier (SUMO) is involved in various cellular processes and mediates known non-covalent protein-protein interactions by three distinct binding surfaces, whose interactions are termed class I to class III.
Kira Brüninghoff +4 more
doaj +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Development of a Middleware between SUMO simulation tool and JaCaMo framework
Advances in Distributed Computing and Artificial Intelligence Journal, 2018 Smart City has an infrastructure that works with technology to reduce daily problems. The lack of parking spots is one of these problems that can be controlled by creating Smart Parking systems.
Alexis van HAARE HEIJMEIJER +1 more
doaj +1 more source