Results 61 to 70 of about 46,190 (264)
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang +8 more
wiley +1 more source
Slx8 removes Pli1-dependent protein-SUMO conjugates including SUMOylated Topoisomerase I to promote genome stability [PDF]
Peer ...
Alexander Lorenz +16 more
core +1 more source
SUMO protease SENP6 protects the nucleus from hyperSUMOylation-induced laminopathy-like alterations
Summary: The small ubiquitin-like modifier (SUMO) protease SENP6 disassembles SUMO chains from cellular substrate proteins. We use a proteomic method to identify putative SENP6 substrates based on increased apparent molecular weight after SENP6 depletion.
Magda Liczmanska +6 more
doaj +1 more source
Abstract This technical note describes an alternative surgical technique for anterior cruciate ligament (ACL) reconstruction combined with anterolateral complex (ALC) augmentation. The procedure uses a hollow ligament advanced reinforcement system (LARS), along with semitendinosus and gracilis tendons as grafts.
Tianhao Zhu +6 more
wiley +1 more source
carlesfernandez/oe-gnss-sdr-manifest: sumo-22.02
Geniux Sumo v22.02 New release of the Geniux Sumo manifest. It contains a list of Git repositories and their respective commit hashes that allow building images and SDKs defined by the meta-gnss-sdr OpenEmbedded layer The name Geniux comes from **G ...
Philip Balister +2 more
core +1 more source
Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda +5 more
wiley +1 more source
Experimental Characterization of Routing Protocols in Urban Vehicular Communication
Vehicular communication is a cynosure in automotive industry these days. V2V communication is one of the types of vehicular communication which render lane change warning, emergency vehicle alert, intersection alert, congestion alert, payment at tolls ...
Punia Divya, Kumar Rajender
doaj +1 more source
Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa +2 more
wiley +1 more source
SUMO: The Glue that Binds [PDF]
Two articles in a recent issue of Molecular Cell (Shen et al., 2006; Lin et al., 2006) demonstrate that noncovalent interactions between the SUMO moieties of SUMO-modified PML, and SUMO binding motifs on PML and other PML nuclear-body-associated proteins, affect the assembly of PML nuclear bodies and the recruitment of proteins in and out of these ...
Matunis, Michael J. +2 more
openaire +3 more sources
<h2>What's Changed</h2> <ul> <li>fix: set traci default view if it doesn't exist by @KevynKelso in https://github.com/LucasAlegre/sumo-rl/pull/191</li> <li><a href="https://github.com/LucasAlegre/sumo-rl/commit ...
Alegre, Lucas N.
core +1 more source

