Results 51 to 60 of about 299,473 (288)

Quantitative SUMO proteomics identifies PIAS1 substrates involved in cell migration and motility

Nature Communications, 2020
The protein inhibitor of activated STAT1 (PIAS1) is an E3 SUMO ligase that plays important roles in various cellular pathways. Increasing evidence shows that PIAS1 is overexpressed in various human malignancies, including prostate and lung cancers.
Chongyang Li, Francis P. McManus, Cédric Plutoni, Cristina Mirela Pascariu, Trent G. Nelson, Lara Elis Alberici Delsin, G. Emery, P. Thibault   +7 more
semanticscholar   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Using bioinformatics to reveal the pathogenic mechanisms of small ubiquitin-like modification in psoriasis and to predict drug sensitivity

Pifu-xingbing zhenliaoxue zazhi
[Objective] Using bioinformatics to assess the expression levels and regulatory mechanisms of small ubiquitin-related modifier (SUMO) in psoriasis, and to analyze its effect on metabolism.
YUAN Liyan, YU Xiaoling, HE Xueyu
doaj   +1 more source

SUMO-Mediated Regulation of Nuclear Functions and Signaling Processes.

Molecules and Cells, 2018
Since the discovery of SUMO twenty years ago, SUMO conjugation has become a widely recognized post-translational modification that targets a myriad of proteins in many processes.
Xiaolan Zhao
semanticscholar   +1 more source

Sensitivity analysis using data-driven parametric macromodels [PDF]

, 2011
An accurate parametric macromodeling method which builds the parameterized frequency behavior of systems from frequency data samples is presented.
Chemmangat Manakkal Cheriya, Krishnan, Dhaene, Tom, Ferranti, Francesco, Knockaert, Luc   +3 more
core   +2 more sources

The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal

Nature Communications, 2020
Nuclear Pore complexes (NPCs) act as docking sites to anchor particular DNA lesions facilitating DNA repair by elusive mechanisms. Using replication fork barriers in fission yeast, we report that relocation of arrested forks to NPCs occurred after Rad51 ...
Karol Kramarz, Kamila Schirmeisen, Virginie Boucherit, Anissia Ait Saada, C. Lovo, Benoît Palancade, C. Freudenreich, S. Lambert   +7 more
semanticscholar   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

EXTRAÇÃO DO SUMO DA BETA VULGARIS COMO ALTERNATIVA SUSTENTÁVEL NA PRODUÇÃO DE TINTAS

Revista UniVap, 2017
O trabalho apresenta a extração do sumo da beterraba a partir de um método simples ao mais complexo, sendo utilizado apenas a pigmentação arrocheada para a fabricação de tinta natural, sem corantes para que não deteriore o material.
Gabriela Camila Ribeiro, Ingrid Januário Santana, Leticia Gabriele Ereno, Maria Laura Castro Villa, Neiva Dias Ambrósio, Jobair Rangel   +5 more
doaj   +1 more source

Practical implementation of a sequential sampling algorithm for EMI near-field scanning [PDF]

, 2012
—In this paper, a practical implementation of a recently proposed automatic and sequential sampling algorithm for the near-field scanning of printed circuit boards and/or integrated circuits is presented.
Boesman, Bart, Couckuyt, Ivo, Deschrijver, Dirk, Dhaene, Tom, Pissoort, Davy, Van der Streek, Bram, Vanhee, Filip   +6 more
core   +2 more sources

SUMO-mediated regulation of NLRP3 modulates inflammasome activity

Nature Communications, 2018
The NLRP3 inflammasome responds to infection and tissue damage, and rapidly escalates the intensity of inflammation by activating interleukin (IL)-1β, IL-18 and cell death by pyroptosis.
R. Barry, Sidonie Wicky John, Gianmaria Liccardi, T. Tenev, I. Jaco, Chih-Hong Chen, Justin Choi, Paulina Kasperkiewicz, T. Fernandes-Alnemri, E. Alnemri, M. Drąg, Yuan Chen, P. Meier   +12 more
semanticscholar   +1 more source