Results 31 to 40 of about 299,473 (288)
The present study investigated the role and mechanism of SUMO2/3 in the protection of vascular endothelial cells by propofol. An ischemia-reperfusion (I/R) injury model of human umbilical vein endothelial cells (HUVECs) was constructed.
Peng Li +3 more
doaj +1 more source
SUMO Signaling by Hypoxic Inactivation of SUMO-Specific Isopeptidases [PDF]
Post-translational modification of proteins with ubiquitin-like SUMO modifiers is a tightly regulated and highly dynamic process. The SENP family of SUMO-specific isopeptidases comprises six cysteine proteases. They are instrumental in counterbalancing SUMO conjugation, but their regulation is not well understood.
Kunz Kathrin +5 more
openaire +5 more sources
Information and communication technology graduates are among the highly skilled, paid, and perceived as capable and credible professionals worldwide. This has resonated in significant growth in the number of students pursuing careers in ICT at various ...
Dorris Zayzay Sumo +2 more
doaj +1 more source
The Sgs1 helicase and Top3-Rmi1 decatenase form a complex that affects homologous recombination outcomes during the mitotic cell cycle and during meiosis.
Matan Cohen, Michael Lichten
doaj +1 more source
Sequential sampling strategy for the modeling of parameterized microwave and RF components [PDF]
Accurate modeling of parameterized microwave and RF components often requires a large number of full-wave electromagnetic simulations. In order to reduce the overall simulation cost, a sequential sampling algorithm is proposed that selects a sparse set ...
Crombecq, Karel +3 more
core +2 more sources
Green corridor is a dynamic real-time lane created in order to increase the speed at which an emergency vehicle can travel in traffic. Its purpose is to reduce the travel time of emergency vehicles.
Yadav Shalini, Rishi Rahul
doaj +1 more source
The role of Schizosaccharomyces pombe SUMO ligases in genome stability [PDF]
SUMOylation is a post-translational modification that affects a large number of proteins, many of which are nuclear. While the role of SUMOylation is beginning to be elucidated, it is clear that understanding the mechanisms that regulate the process is ...
A. Skilton +44 more
core +2 more sources
Sumo-dependent substrate targeting of the SUMO protease Ulp1 [PDF]
AbstractBackgroundIn the yeastSaccharomyces cerevisiae, the essential small ubiquitin-like modifier (SUMO) protease Ulp1 is responsible for both removing SUMO/Smt3 from specific target proteins and for processing precursor SUMO into its conjugation-competent form.
Westerbeck Jason W +5 more
openaire +3 more sources
Generating sequential space-filling designs using genetic algorithms and Monte Carlo methods [PDF]
In this paper, the authors compare a Monte Carlo method and an optimization-based approach using genetic algorithms for sequentially generating space-filling experimental designs.
D. Gorissen +9 more
core +2 more sources
A Chain of Events: Regulating Target Proteins by SUMO Polymers.
Small ubiquitin-like modifiers (SUMOs) regulate virtually all nuclear processes. The fate of the target protein is determined by the architecture of the attached SUMO protein, which can be of polymeric nature.
Nicolette S. Jansen, A. Vertegaal
semanticscholar +1 more source

