Results 41 to 50 of about 46,190 (264)

Organizational and managerial bases of activity of the Kharkiv Regional Sumo Federation

Слобожанський науково-спортивний вісник, 2019
Purpose: to characterize the organizational and managerial bases for the activity of the Kharkiv Regional Sumo Federation. Material & Methods: the study analyzed the Charter of the Kharkiv Regional Sumo Federation, training programs on sumo, to assess ...
Ruslan Bairamov, Anastasia Bondar
doaj   +1 more source

K-bZIP Mediated SUMO-2/3 Specific Modification on the KSHV Genome Negatively Regulates Lytic Gene Expression and Viral Reactivation. [PDF]

PLoS Pathogens, 2015
SUMOylation is associated with epigenetic regulation of chromatin structure and transcription. Epigenetic modifications of herpesviral genomes accompany the transcriptional switch of latent and lytic genes during the virus life cycle.
Wan-Shan Yang, Hung-Wei Hsu, Mel Campbell, Chia-Yang Cheng, Pei-Ching Chang   +4 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Diversification of SUMO-Activating Enzyme in Arabidopsis: Implications in SUMO Conjugation [PDF]

Molecular Plant, 2013
Sumoylation is an essential posttranslational modification that participates in many biological processes including stress responses. However, little is known about the mechanisms that control Small Ubiquitin-like MOdifier (SUMO) conjugation in vivo. We have evaluated the regulatory role of the heterodimeric E1 activating enzyme, which catalyzes the ...
L. Castano-Miquel, J. Segui, S. Manrique, I. Teixeira, L. Carretero-Paulet, F. Atencio, L. M. Lois   +6 more
openaire   +3 more sources

PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation [PDF]

, 2014
Arsenic is a clinically effective treatment for acute promyelocytic leukaemia (APL) in which the promyelocytic leukaemia (PML) protein is fused to retinoic receptor alpha (RARα).
Hands, K.J., Hay, Ronald T., Everett, R.D., Hay, R.T., Hands, Katherine J., Cuchet-Lourenco, Delphine, Everett, Roger D., Cuchet-Lourenco, D.   +7 more
core   +1 more source

Using bioinformatics to reveal the pathogenic mechanisms of small ubiquitin-like modification in psoriasis and to predict drug sensitivity

Pifu-xingbing zhenliaoxue zazhi
[Objective] Using bioinformatics to assess the expression levels and regulatory mechanisms of small ubiquitin-related modifier (SUMO) in psoriasis, and to analyze its effect on metabolism.
YUAN Liyan, YU Xiaoling, HE Xueyu
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

SUMO Wrestling with Specificity [PDF]

Structure, 2002
A new structure reveals how substrates are recognized for conjugation to the ubiquitin-like protein SUMO, a posttranslational modification that functions in activation of transcription factors, nuclear import, and cell division.
VanDemark, Andrew P, Hill, Christopher P
openaire   +2 more sources

EXTRAÇÃO DO SUMO DA BETA VULGARIS COMO ALTERNATIVA SUSTENTÁVEL NA PRODUÇÃO DE TINTAS

Revista UniVap, 2017
O trabalho apresenta a extração do sumo da beterraba a partir de um método simples ao mais complexo, sendo utilizado apenas a pigmentação arrocheada para a fabricação de tinta natural, sem corantes para que não deteriore o material.
Gabriela Camila Ribeiro, Ingrid Januário Santana, Leticia Gabriele Ereno, Maria Laura Castro Villa, Neiva Dias Ambrósio, Jobair Rangel   +5 more
doaj   +1 more source

Spin‐Split Edge States in Metal‐Supported Graphene Nanoislands Obtained by CVD

Advanced Materials, EarlyView.
Combining STM measurements and ab‐initio calculations, we show that zig‐zag edges in graphene nanoislands grown on Ni(111) by CVD retrieve their spin‐polarized edge states after intercalation of a few monolayers of Au. ABSTRACT Spin‐split states localized on zigzag edges have been predicted for different free‐standing graphene nanostructures.
Michele Gastaldo, Masoud Mansouri, Carlos Garcia‐Fernandez, Daniel Sánchez‐Portal, Aran Garcia‐Lekue, Gustavo Ceballos, Aitor Mugarza   +6 more
wiley   +1 more source