Results 221 to 230 of about 300,823 (367)

BALIKESİR SANAYİ 1-2 NOLU KAVŞAKLARIN SUMO İLE KENTSEL HAREKETLİLİK ANALİZİ

Gülten Bayram, Mustafa Ilıcalı
openalex   +2 more sources

Semantic primitives and compositionality: An Annual Review of Information Science and Technology (ARIST) paper

Journal of the Association for Information Science and Technology, Volume 77, Issue 1, Page 198-223, January 2026.
Abstract The term semantic primitives refers to a set of basic, atomic concepts from which all other (compound) concepts are constructed. It presupposes the principle of compositionality—the idea that complex items or expressions can be formed by combining simpler constituents.
Birger Hjørland
wiley   +1 more source

New Insights into TFEB SUMOylation and Its Role in Lipid Metabolism and Cardiovascular Disease. [PDF]

Int J Mol Sci
Meng Q, Li CG, Chen X, Cao R, Zhang H, Wang P, Jin J.   +6 more
europepmc   +1 more source

SUMO-2 activity is inhibited by non-covalent interactions with the Aβ peptide: an exploration of potential pathogenic mechanisms in Alzheimer's disease

Valeria Ciaffaglione, Giulia Grasso, Valeria Lanza, Michele F. M. Sciacca, Stefania Zimbone, Maria Laura Giuffrida, Claudio Iacobucci, Alessio Di Ianni, Damiano Calcagno, Giuseppe Grasso, Andrea Alloni, Franca Orsini, Paul Fraser, Luana Fioriti, Danilo Milardi   +14 more
openalex   +1 more source

TDP‐43 Phosphorylation: Pathological Modification or Protective Factor Antagonizing TDP‐43 Aggregation in Neurodegenerative Diseases?

BioEssays, Volume 48, Issue 1, January 2026.
TDP‐43 hyperphosphorylation occurs in neurodegenerative diseases, however, it is not a driver of TDP‐43 aggregation, but enhances TDP‐43 solubility, suggesting that TDP‐43 hyperphosphorylation is protective. Toxicity may arise from a broader phosphorylation‐driven cellular pathway disruption.
Simone Mosna, Dorothee Dormann
wiley   +1 more source

Pathogen-induced hijacking of host SUMOylation: from molecular mechanisms and prospects for therapeutic modulation. [PDF]

Front Immunol
Padmakumar S, Madhavan A, Nair BG, Kumar GB.   +3 more
europepmc   +1 more source

Supplementary Data Methods from T Cell–intrinsic Immunomodulatory Effects of TAK-981 (Subasumstat), a SUMO-activating Enzyme Inhibitor, in Chronic Lymphocytic Leukemia

Vi Lam, Carly Roleder, Tingting Liu, Nur Bruss, Scott Best, Xiaoguang Wang, Tycel Phillips, Geoffrey Shouse, Allison J. Berger, Lapo Alinari, Lili Wang, Tanya Siddiqi, Nathan D. Pennock, Alexey V. Danilov   +13 more
openalex   +1 more source

Zipping up the Synaptonemal Complex: Pathways to Homologous Chromosome Synapsis

BioEssays, Volume 48, Issue 1, January 2026.
The synaptonemal complex (SC) is a conserved protein structure that assembles between homologous chromosomes during meiosis. Here, we review pathways promoting homologous synapsis across model organisms, examining coordination with homolog pairing and recombination, spatiotemporal regulation of SC assembly, and the conserved molecular modules coupling ...
Ariel L. Gold, Yumi Kim
wiley   +1 more source

Sumoylation of cyclin and its therapeutic potential for cancer. [PDF]

Anim Cells Syst (Seoul)
Ryu HY, Hochstrasser M.
europepmc   +1 more source

Proteomic and Ubiquitinated Proteome Insights Into ER Stress Responses in Chinese Hamster Ovary Cells Under Mild Hypothermic Conditions

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 5-25, January 2026.
Proteomic analysis of CHO cells under mild hypothermia (31°C) reveals ER stress responses, ubiquitination dynamics, and adaptive mechanisms. Magnetic immuno‐affinity enrichment and mass spectrometry highlight protein regulation differences in non‐producer versus producer cells, offering insights for optimising biopharmaceutical production of IgG1 and ...
David Ryan, Christiana‐Kondylo Sideri, Michael Henry, Selvaprakash Karuppuchamy, Esen Efeoglu, Paula Meleady   +5 more
wiley   +1 more source