Results 221 to 230 of about 291,935 (374)

Correlating membrane‐protein dynamics with function: Integrating bioinformatics, molecular dynamics, and single‐molecule FRET

open access: yesProtein Science, Volume 34, Issue 11, November 2025.
Abstract We present a strategy that deploys structural bioinformatics, molecular simulation, and single‐molecule Förster Resonance Energy Transfer (FRET) microscopy for observing the ligand‐dependent conformational dynamics of integral membrane proteins in situ.
Hugh R. Higinbotham   +2 more
wiley   +1 more source

Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1)

open access: green, 2000
Hetti Poukka   +3 more
openalex   +1 more source

Polymeric Chains of SUMO-2 and SUMO-3 Are Conjugated to Protein Substrates by SAE1/SAE2 and Ubc9 [PDF]

open access: hybrid, 2001
Michael H. Tatham   +6 more
openalex   +1 more source

Extensive TDDFT Benchmark Study of the Resonance Raman Spectra of Lumiflavin

open access: yesJournal of Computational Chemistry, Volume 46, Issue 26, October 5, 2025.
An extensive computational TDDFT resonance Raman study of lumiflavin is presented including forty‐two different DFT functionals, benchmarked against the experimental spectra of FMN. The inclusion of resonance enhancements improved the agreement for most functionals.
Prokopis C. Andrikopoulos, Heba Halimeh
wiley   +1 more source

Human Schlafen 14 Cleavage of Short Double‐Stranded RNAs Underpins its Antiviral Activity

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
SLFN14 is associated with human diseases. SLFN14 is found to cleave RNAs containing short duplexes. The cryo‐EM structures of SLFN14 and SLFN14‐hairpin RNA complex reveal that SLFN14 assembles into a ring‐like dimer; two RNase domains form an RNA‐binding groove accommodating a hairpin RNA.
Mengyun Li   +8 more
wiley   +1 more source

Progastrin Promotes Colorectal Cancer Stem Cell‐Like Properties via the Receptor PZR

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
The tumor microenvironment supports colorectal cancer (CRC) progression by maintaining cancer stem cells (CSCs) through progastrin (PG). This study identifies Protein Zero‐Related protein (PZR) as an essential receptor for PG activity, promoting CSC‐like signaling via SHP2/SRC/β‐catenin.
Julie Nguyen   +22 more
wiley   +1 more source

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