Results 261 to 270 of about 291,935 (374)

UFMylation System: Biological Functions, Molecular Mechanisms, Diseases, and Drug Discovery

open access: yesMedComm, Volume 6, Issue 10, October 2025.
UFMylation, a novel ubiquitin‐like modification, plays an essential role in various cellular processes, such as the immune response, DNA damage repair, unfolded protein response (UPR), autophagy, endoplasmic reticulum (ER)‐phagy, stem cell self‐renewal, apoptosis, and metastasis.
Huiyan Li   +5 more
wiley   +1 more source

SUMO-1 and p53 [PDF]

open access: bronze, 2002
Frauke Melchior, Ludger Hengst
openalex   +1 more source

Competing chaperone pathways in α‐synuclein disaggregation and aggregation dynamics

open access: yesProtein Science, Volume 34, Issue 10, October 2025.
Abstract The aggregation of the protein α‐synuclein into amyloid fibrils and their subsequent deposition into large proteinaceous inclusions is a pathological hallmark of several neurodegenerative diseases, including Parkinson's disease. Molecular chaperones, including the small heat‐shock proteins (sHsps) and the Hsp70 chaperone system, are known to ...
Nicola K. Auld   +4 more
wiley   +1 more source

The Aryl Hydrocarbon Receptor Nuclear Transporter Is Modulated by the SUMO-1 Conjugation System [PDF]

open access: hybrid, 2002
Masahide Tojo   +8 more
openalex   +1 more source

A third type of PETase from the marine Halopseudomonas lineage

open access: yesProtein Science, Volume 34, Issue 10, October 2025.
Abstract The enzymatic degradation of polyethylene terephthalate (PET) offers a sustainable solution for PET recycling. Over the past two decades, more than 100 PETases have been characterized, primarily exhibiting similar sequences and structures.
Onur Turak   +8 more
wiley   +1 more source

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