The mechanism of nesprin-2 accumulation at the nucleus front during confined cell migration. [PDF]
Biophys JBos I +6 more
europepmc +1 more source
Vascular endothelial-specific loss of TGF-beta signaling as a model for choroidal neovascularization and central nervous system vascular inflammation. [PDF]
ElifeWang Y +4 more
europepmc +1 more source
Persistent open chromatin state in early-life stress-activated cells of the VTA. [PDF]
Sci RepRashford RL +4 more
europepmc +1 more source
A mouse model engineered to spatiotemporally control Cre expression in progesterone receptor positive cells†. [PDF]
Biol ReprodQuiroz E +8 more
europepmc +1 more source
Integration of nuclear mechanosensing with integrin-extracellular matrix adhesions. [PDF]
NucleusSandria S, King MC.
europepmc +1 more source
Mechanical coordination of counter-gradient growth maintains organ curvature in the apical hook
Robert S +13 more
europepmc +1 more source
Reversal of laminopathies: the curious case of SUN1 [PDF]
Nucleus, 2012 Mutations in the LMNA gene are associated with a spectrum of human dystrophic diseases termed the "nuclear laminopathies." We recently found that the accumulation of the inner nuclear envelope proteins SUN1 is pathogenic in progeric and dystrophic laminopathies. This conclusion arose from the unexpected observation that the deletion of Sun1, instead of
Ya-Hui Chi, Chia-Yen Chen
exaly +3 more sources
Sun1 forms immobile macromolecular assemblies at the nuclear envelope
Biochimica Et Biophysica Acta - Molecular Cell Research, 2008 SUN-domain proteins form a novel and conserved family of inner nuclear membrane (INM) proteins, which establish physical connections between the nucleoplasm and the cytoskeleton. In the current study, we provide evidence that within the nuclear envelope (NE) Sun1 proteins form highly immobile oligomeric complexes in interphase cells.
Jan Ellenberg +2 more
exaly +3 more sources