Results 1 to 10 of about 514 (160)

A Study for the Restoration of the Sundials in King Sejong Era [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2011
The sundials produced in King Sejong era had the functions of accurate observation instruments and were fabricated in various forms such as Angbuilgu (hemispherical sundial). In this study, we investigated the literature, structural characteristics and
Sang-Hyuk Kim
exaly   +2 more sources

Accurate and Efficient Numerical Simulation of Land Models Using SUMMA With SUNDIALS [PDF]

open access: yesJournal of Advances in Modeling Earth Systems
Numerical simulation of land models without error control can be highly inaccurate. We present the incorporation of the Suite of Nonlinear and Differential‐Algebraic Equation Solvers (SUNDIALS) package to solve the equations that simulate thermodynamics ...
Raymond J. Spiteri   +7 more
doaj   +2 more sources

Integrating B Cell Differentiation Model With Real-World Data Informs Determinants for Antibody-Secreting Cell Depletions in Systemic Sclerosis. [PDF]

open access: yesCPT Pharmacometrics Syst Pharmacol
ABSTRACT Systemic sclerosis (SSc) is a complex autoimmune disorder characterized by extensive fibrosis, vascular abnormalities, and immune dysregulation, affecting clinical outcomes such as skin thickness and pulmonary function with high mortality rates. B cells play a pivotal role in the pathogenesis of SSc. This study aimed to develop a systems model
Nakada T   +8 more
europepmc   +2 more sources

Sundials/ML: Connecting OCaml to the Sundials Numeric Solvers [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2018
This paper describes the design and implementation of a comprehensive OCaml interface to the Sundials library of numeric solvers for ordinary differential equations, differential algebraic equations, and non-linear equations.
Timothy Bourke, Jun Inoue, Marc Pouzet
doaj   +5 more sources

Linking Abundance and Activity of Ammonia-Oxidising Bacteria and Archaea in an Agriculturally Impacted First-Order Stream. [PDF]

open access: yesEnviron Microbiol
Ammonia‐oxidising archaea (AOA) and bacteria (AOB) coexist in streambed sediments, but their contributions to nitrification remain unresolved. Using field sampling, sequencing, qPCR, microcosm incubations and modelling, we show that AOB dominated nitrification in streambed sediments despite lower abundance, emphasizing the importance of distinguishing ...
Wang Z   +6 more
europepmc   +2 more sources

Integrative QSP Modeling of Cancer Stem Cells in Triple-Negative Breast Cancer: Impacts on Tumor Immunity and Response to Immune Checkpoint Inhibitors. [PDF]

open access: yesCPT Pharmacometrics Syst Pharmacol
ABSTRACT Cancer stem cells (CSCs) contribute to an immunosuppressive microenvironment through complex mechanisms and tumor‐immune interactions. However, the key determinants of CSC characteristics in driving tumor progression, immune suppression, and response to ICIs remain unclear and require systematic investigation.
Xue J   +10 more
europepmc   +2 more sources

B Cell Differentiation Model for Identifying Predictors of Responses to Rituximab-Mediated B Cell Depletion in Rheumatic Diseases. [PDF]

open access: yesCPT Pharmacometrics Syst Pharmacol
ABSTRACT Rituximab (RTX), an anti‐CD20 monoclonal antibody, has been used to treat autoimmune diseases such as rheumatoid arthritis (RA). However, variability in therapeutic response to RTX remains a challenge. Here, a systems model is developed to mimic B cell differentiation leading to antibody‐secreting cells (ASCs), including plasmablasts (PBs) and
Nakada T, Mager DE.
europepmc   +2 more sources

Time Tools. [PDF]

open access: yesTop Cogn Sci
Abstract Many core human activities require an understanding of time. To coordinate rituals, plan harvests and hunts, recall histories, keep appointments, and follow recipes, we need to grapple with invisible temporal structures like durations, sequences, and cycles. No other species seems to do this.
Cooperrider K.
europepmc   +2 more sources

Investigating and Analyzing Decorative Designs of «Non-Observational Astronomical Instruments» of the Safavid Period [PDF]

open access: yesپیکره, 2023
Introduction: Astronomical instruments were made in different eras to observe the condition of stars, to identify the time, and to predict the future. They were produced for observatories in large dimensions and for scientists in small and portable sizes.
Afsaneh Boveyri, Mitra Shateri
doaj   +1 more source

A Study on the Sundials of the Kang Family of Jinju [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2010
In this paper, we investigate the sundials made by the Kang Family of Jinju in the later period of the Joseon dynasty in terms of their characteristics, functions and the manufacturing technique. One of the characteristics of these sundials is that the
Sang Hyuk Kim, Ki-Won Lee, Yong Sam Lee
doaj   +1 more source

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