Results 61 to 70 of about 529,498 (302)
Clinical & Translational Immunology, 2020 Bipolar disorder (BD) is a chronic disease characterised by episodes of major depression and episodes of mania or hypomania, with a worldwide prevalence of 2.4%. The cause of BD is unknown.
Michael P Pender
doaj +1 more source
Solar Tests of Aperture Plate Materials for Solar Thermal Dish Collectors [PDF]
, 1983 If a malfunction occurs in a solar thermal point-focus distributed receiver power plant while a concentrator is pointed at the Sun, motion of the concentrator may stop. As the Sun moves relative to the Earth, the spot of concentrated sunlight then slowly
Jaffe, L. D.
core +2 more sources
Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen +10 more
wiley +1 more source
The Role of the Gut Microbiota in Individuals with Irritable Bowel Syndrome: A Scoping Review
MedicinaIrritable bowel syndrome (IBS) represents the most prevalent disorder of brain–gut interaction, affecting approximately 10% of the global population. The objective of this study was to examine the mechanisms by which the gut microbiota contributes to the
Takahiko Nagamine
doaj +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Xeroderma pigmentosum: when the sun burns the eyes
PAMJ Clinical Medicine, 2020 We report the case of a two-month-old male infant from a consanguine marriage. He had pigmented lesions on the skin of the eyelids, the face, and the neck, alternating with areas of depigmentation.
Aymane Ridallah, Lalla Ouafaa Cherkaoui
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Spiky ice and penitente tilting [PDF]
, 2018 Indexación: Scopus.Under certain conditions, at high altitude, the surface of snow develops spike-like structures known as penitentes. This is a rather counterintuitive phenomenon, which is a consequence of surface sublimation at a given point as a ...
Guilleminot, P., Olea, R.
core +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
A portable device for nucleic acid quantification powered by sunlight, a flame or electricity. [PDF]
, 2018 A decentralized approach to diagnostics can decrease the time to treatment of infectious diseases in resource-limited settings. Yet most modern diagnostic tools require stable electricity and are not portable.
Cesarman, Ethel +8 more
core +1 more source