Results 31 to 40 of about 4,747 (288)

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Differential Rotation of Individual Sunspots and Pores

The Astrophysical Journal
The analysis of the rotation rate of individual sunspots and pores was performed according to the data from the processing of observations by the Solar Dynamics Observatory/Helioseismic and Magnetic Imager in the period 2010–2024.
Andrey G. Tlatov, Kseniya A. Tlatova
doaj   +1 more source

Retinal Vessel Segmentation: A Comprehensive Review From Classical Methods to Deep Learning Advances (1982–2025)

Advanced Intelligent Systems, EarlyView.
Four decades of retinal vessel segmentation research (1982–2025) are synthesized, spanning classical image processing, machine learning, and deep learning paradigms. A meta‐analysis of 428 studies establishes a unified taxonomy and highlights performance trends, generalization capabilities, and clinical relevance.
Avinash Bansal, Jan Kubíček, Jana Bahrová, Alice Varyšová, Martin Augustýnek, Marek Penhaker, Juraj Timkovič   +6 more
wiley   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Propagation Properties of Sunspots Umbral Oscillations in Horizontal and Vertical Directions

The Astrophysical Journal, 2023
We present a study on investigating the propagation characteristics of umbral oscillations in sunspots. In sunspot 1 (located in NOAA AR 12127) with four umbrae, the analysis shows that the oscillations in different umbrae are correlated.
Wei Wu, Jiang-tao Su, Jie Chen, Xiao-shuai Zhu, Robert Sych   +4 more
doaj   +1 more source

A perspective from the Mesozoic: Evolutionary changes of the mammalian skull and their influence on feeding efficiency and high‐frequency hearing

The Anatomical Record, EarlyView.
Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley   +1 more source

Do Sunspots Matter under Complete Ignorance?

, 2006
In a two-period, sunspot, pure-exchange economy we analyze the case in which agents do not assign subjective probabilistic beliefs to the "sunspot activity". Two generations, each of which is made up of identical agents, populate this economy.
Giordani, P.E., GIORDANI, Paolo, Cozzi, G., Cozzi, Guido, Giordani, Paolo E., Cozzi, G   +5 more
core   +1 more source

The Decay of Two Adjacent Sunspots Associated with Moving Magnetic Features

The Astrophysical Journal
The relationship between the decay of sunspots and moving magnetic features (MMFs) plays an important role in understanding the evolution of active regions.
Yang Peng, Zhike Xue, Zhongquan Qu, Jincheng Wang, Zhe Xu, Liheng Yang, Yian Zhou   +6 more
doaj   +1 more source

Chlorella vulgaris biorefineries: sustainable biofuels and high‐value carbon capture

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Global reliance on fossil fuels has created urgent economic and environmental challenges, yet large‐scale use of algal biomass remains limited by production costs. Industrial scaling is constrained by inefficient harvesting and the technical challenges of processing recalcitrant cell walls.
Sandyelle Ferreira Alcântara Araújo, Antonio Átila Menezes Ferreira, Lucia Andrea Sindeaux de Oliveira, Dayana Nascimento Dari, Devany Quintela Soares, Eliana Elisa Francelino Mavie, Francisco Leonardo Alves de Moraes Sousa, Jessica Lopes da Silva, João Vitor Gomes de Araújo Silva, Thiago Queiroz da Silva, Ana Karine Portela Vasconcelos, Kelma Maria dos Santos Pires Cavalcante, John Hebert da Silva Felix, José Cleiton Sousa dos Santos   +13 more
wiley   +1 more source

Rotating Sunspots and Solar Eruptions

, 2012
In this presentation, we first introduced the definition and classification of rotating sunspots. Using multi-wavelength data, we investigated the evolution of some rotating sunspots and the response of upper atmosphere relevant to the rotating sunspots.
X.L. Yan, Z.Q. Qu
core   +1 more source