Results 61 to 70 of about 4,747 (288)

Spatiotemporal Evolution of Hydroclimatic Variables in the Brazilian Semi‐Arid Region Through the Aridity Index and Susceptibility to Desertification

open access: yesInternational Journal of Climatology, EarlyView.
Over the past 60 years, noticeable changes have been observed in the main hydroclimatological variables, driven by both natural and anthropogenic factors. In the context of climate change, such behaviour may adversely affect the state's economic activities, as well as increase the recurrence of extreme events in the region.
Ronaldo Guilherme Santos Lima   +4 more
wiley   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

open access: yesNeuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji   +4 more
wiley   +1 more source

Diagnosing the 11‐year solar cycle's influence on the East Atlantic pattern

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
A previously unidentified solar‐cycle response in the East Atlantic pattern is found in late winter at lag +3 years with larger amplitude than the NAO response. A statistically significant NAO response to the solar cycle is seen in late winter at lag 0 years.
Stergios Misios   +4 more
wiley   +1 more source

Analyzing the inter-annual variability of rainfall in the Brazilian semi-arid region

open access: yesActa Scientiarum: Technology
This research aims to analyze the interannual variability of rainfall and the correlation between solar cycles and teleconnections with the precipitation regime of the Intermediate Geographic Region of Caicó (IGRC), in the semiarid region of the state ...
Francisco Monteiro   +2 more
doaj   +1 more source

Meridional motions of sunspots and sunspot groups

open access: yesThe Astrophysical Journal, 1986
Etude des positions des taches solaires et des groupes de taches determinees au Mont Wilson en lumiere blanche entre 1917 et 1983, afin d'examiner la nature des mouvements meridiens des taches et groupes durant cet ...
R. Howard, P. A. Gilman
openaire   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick   +7 more
wiley   +1 more source

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova   +5 more
wiley   +1 more source

Modern View of the Sun: Materials for an Experimental History at the Dawn of the Telescopic Era

open access: yesHistories
Galileo and the telescope revolutionized the concept of the Sun. The discovery of its rotation was possible due to the continuous observation of the sunspots. The faculae and the maculae with umbra and penumbra became accessible daily to new instruments,
Costantino Sigismondi
doaj   +1 more source

Prognostic factors of optical coherence tomography angiography in intermediate and advanced primary open‐angle glaucoma: A systematic review and meta‐analysis

open access: yesActa Ophthalmologica, EarlyView.
Abstract Conventional optical coherence tomography (OCT) has a floor effect in patients with severe visual field loss, such as seen in advanced primary open‐angle glaucoma (POAG). OCT angiography (OCTA) does not suffer from such a floor effect. However, which OCTA parameters are most useful for monitoring longitudinal progression is unclear.
Kamya Katarya   +5 more
wiley   +1 more source

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