Results 81 to 90 of about 1,242 (240)

Macular telangiectasia type 2 genetic risk variants associated with clinical characteristics in the Slovenian cohort

Acta Ophthalmologica, EarlyView.
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič, Nataša Debeljak, Petra Hudler, Janez Smerkolj, Mojca Urbančič   +4 more
wiley   +1 more source

Inter‐eye microvascular asymmetry across stages of diabetic retinopathy: An OCT angiography study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate inter‐eye asymmetry in macular microvascular parameters across different stages of diabetic retinopathy (DR) using OCT angiography, and to explore the associations with clinical factors. Methods This cross sectional study included 442 eyes of 221 patients with diabetes mellitus type 2. Central subfield thickness (CST), area
Stela Vujosevic, Sema Tamer Kaderli, Gabriele Piccoli, Elena Tagliabue, Camilla Alovisi, Vanda Bucceri, Emanuele Torti, Elisa Marenzi, Dogukan Ozen, Livio Luzi, Paolo Nucci   +10 more
wiley   +1 more source

Explainable deep learning self‐supervised vision transformer for fundus‐based myopia classification

Acta Ophthalmologica, EarlyView.
Abstract Purpose To develop and validate a self‐supervised vision transformer (ViT) for automated three‐class classification of Normal, High Myopia (HM), and Pathologic Myopia (PM) from colour fundus photographs, with anatomically faithful interpretability. Methods A DINOv2 self‐supervised ViT was fine‐tuned using a two‐stage transfer‐learning protocol
Eirini Maliagkani, Christos Tsoutsas, Nikolaos Papageorgiou, Ioannis D. Apostolopoulos, Nikolaos Papandrianos, Ilias Georgalas, Elpiniki Papageorgiou   +6 more
wiley   +1 more source

Systematic quantification of outer retinal morphology in three different SD‐OCT devices in geographic atrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To define interdevice differences in quantitative outer retinal biomarkers across three spectral‐domain (SD) optical coherence tomography (OCT) devices in geographic atrophy (GA). Methods Patients with GA prospectively underwent imaging using Spectralis (Heidelberg Engineering), Cirrus (Zeiss) and Maestro (Topcon) OCT devices ...
Klaudia Birner, Sophie Frank‐Publig, Julia Mai, Anna Eidenberger, Johannes Schrittwieser, Gabriel Leitner‐Barrios, Magdalena Barasits, Markus Gumpinger, Gregor S. Reiter, Stefan Sacu, Ursula Schmidt‐Erfurth   +10 more
wiley   +1 more source

Exploring spatial and temporal patterns across solar cycles: Focusing on active longitudes

Astronomy & Astrophysics
Context. Active longitudes (ALs) are proposed behavioural patterns on the Sun, whereby certain solar phenomena tend to appear at preferred longitudes, with these longitudes shifting over time on a scale of a few Carrington rotations (CRs).
Császár K., Korsós M. B., Soós Sz., Erdélyi R.   +3 more
doaj   +1 more source

Modelling solar radial velocities and photometric variability with SOAP

Astronomy & Astrophysics
Context. Stellar activity remains one of the main limitations in the detection of Earth-like planets using radial velocity (RV) measurements. The Sun, as the only star for which surface features can be spatially resolved, offers a unique testbed for ...
Barka A., Cristo E., Santos Â. R. G., Santos N. C., Al Moulla K., Barata T., Gafeira R., Cretignier M.   +7 more
doaj   +1 more source

A novel myopathy with autophagic vacuoles associated with biallelic variants in CLN8

Brain Pathology, EarlyView.
We describe a novel adult‐onset myopathy with autophagic vacuoles and characteristic features of ceroid lipofuscinosis associated with biallelic CLN8 variants, seizures, and muscle weakness. Autophagosomal/lysosomal deposition of curvilinear, autofluorescent material containing the mitochondrial adenosine triphosphate (ATP) synthase membrane subunit c ...
Ulrika Lindgren, Carola Hedberg‐Oldfors, Kittichate Visuttijai, Sara Nordström, Hans Goebel, Anders Oldfors   +5 more
wiley   +1 more source

Magnetic structure of coronal dark halos

Astronomy & Astrophysics
Context. At low coronal temperatures around or below 1 MK distinct areas in the surroundings of active regions (ARs) show emission at a level significantly below the emission coming from the quiet Sun (QS). These areas are referred to as dark halos, dark
Nölke J. D., Solanki S. K., Hirzberger J., Peter H., Chitta L. P., Glassmeier K. H., Calchetti D., Valori G.   +7 more
doaj   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

In-flight calibration of RADEM, the JUICE mission radiation monitor

Astronomy & Astrophysics
Context. The RADiation-hard Electron Monitor (RADEM) aboard the JUpiter ICy moons Explorer (JUICE) mission, launched on April 14, 2023, measures high-energy protons and electrons during the cruise phase and will continue to do so during the nominal ...
Pinto M., Santos F., Gomes A., Gonçalves T. M., Arruda L., Gonçalves P., Rodríguez-García L., Vainio R., Witasse O., Altobelli N.   +9 more
doaj   +1 more source