Results 51 to 60 of about 4,267 (203)

suPAR – A Future Prognostic Biomarker in Emergency Medicine [PDF]

The Journal of Emergency Medicine, 2015
Background Efficient triage in the Emergency Departments (ED) is important to identify patients in need of urgent care. Biomarker measurements may aid these clinical decisions. suPAR, soluble urokinase-type plasminogen activator receptor, is a non-specific biomarker reflecting inflammation and is a strong prognostic marker for several diseases.
Østervig, Rebecca M, Køber, Lars, Forberg, Jakob L, Rasmussen, Lars S, Eugen-Olsen, Jesper, Iversen, Kasper   +5 more
openaire   +1 more source

The Association of uPA, uPAR, and suPAR System with Inflammation and Joint Damage in Rheumatoid Arthritis: suPAR as a Biomarker in the Light of a Personalized Medicine Perspective

, 2022
Background: In recent years, the involvement of the soluble urokinase Plasminogen Activator Receptor (suPAR) in the pathophysiological modulation of Rheumatoid Arthritis (RA) has been documented, resulting in the activation of several intracellular ...
Grossi, Valentina, Mariangela Manfredi, Francesca Li Gobbi, Maria Infantino, Infantino, Maria, Edda Russo, Valentina Grossi, Amedeo Amedei, Serena Guiducci, Fusi, Paola, Benucci, Maurizio, Arianna Damiani, Guiducci, Serena, Maurizio Benucci, Li Gobbi, Francesca, Paola Fusi, Amedei, Amedeo, Damiani, Arianna, Russo, Edda, Manfredi, Mariangela   +19 more
core   +1 more source

Preoperative Plasma Soluble Urokinase Plasminogen Activator Receptor as a Prognostic Marker in Rectal Cancer Patients. An Eortc-Receptor and Biomarker Group Collaboration

The International Journal of Biological Markers, 2005
Background and aims Since approximately 30% of patients with Dukes’ stage B colorectal cancer will experience disease recurrence within five years of primary treatment, current staging of patients with early colorectal cancer apparently fails to ...
R. Riisbro, I.J. Christensen, H.J. Nielsen, N. Brünner, M. Nilbert, E. Fernebro   +5 more
doaj   +1 more source

Soluble urokinase plasminogen activator receptor (suPAR) and glomerular disease in children: a narrative review

Egyptian Pediatric Association Gazette, 2022
Background Focal segmental glomerulosclerosis (FSGS) is a chronic glomerular disease that responds poorly to treatment, with a large proportion of patients progressing to end-stage renal disease in spite of initial aggressive treatment.
Phuong Anh Le Thy, Thuy Yen Hoang Thi, Kiem Hao Tran, Huu Son Nguyen   +3 more
doaj   +1 more source

Serum Levels of Soluble Urokinase Plasminogen Activator Receptor Predict Tumor Response and Outcome to Immune Checkpoint Inhibitor Therapy

Frontiers in Oncology, 2021
BackgroundImmune checkpoint inhibitors (ICIs) have led to a paradigm shift in cancer therapy, improving outcomes in the treatment of various malignancies. However, not all patients benefit to the same extend from ICI.
Sven H. Loosen, Sven H. Loosen, Joao Gorgulho, Joao Gorgulho, Markus S. Jördens, Maximilian Schulze-Hagen, Fabian Beier, Mihael Vucur, Anne T. Schneider, Christiane Koppe, Alexander Mertens, Jakob N. Kather, Frank Tacke, Verena Keitel, Tim H. Brümmendorf, Christoph Roderburg, Christoph Roderburg, Tom Luedde   +17 more
doaj   +1 more source

Evaluation of soluble urokinase-type plasminogen activator receptor (suPAR) quick test for triage in the emergency department

Journal of Family Medicine and Primary Care, 2019
Background: *Soluble urokinase-type plasminogen activator receptor (suPAR) is a new biomarker, which is increased in conditions associated with inflammatory immune cell activation. In low resource, densely populated countries, there is a need for a quick
Pratyush Kumar, Atul Kakar, Atul Gogia, NIamatullah Waziri   +3 more
doaj   +1 more source

Relationship of circulating soluble urokinase plasminogen activator receptor (suPAR) levels to disease control in asthma and asthmatic pregnancy. [PDF]

PLoS ONE, 2013
Asthma has a high burden of morbidity if not controlled and may frequently complicate pregnancy, posing a risk for pregnancy outcomes. Elevated plasma level of the inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is related
István Ivancsó, Gergely Toldi, Anikó Bohács, Noémi Eszes, Veronika Müller, János Rigó, Barna Vásárhelyi, György Losonczy, Lilla Tamási   +8 more
doaj   +1 more source

Inflammatory Biomarkers Predicting Major Adverse Cardiovascular Events in People Living With HIV: A Systematic Review and Meta‐Analysis

Journal of the International AIDS Society, Volume 29, Issue 4, April 2026.
ABSTRACT Introduction Chronic inflammation is a unique contributor to cardiovascular disease (CVD) risk among people living with HIV, yet there is a lack of consensus on the predictive utility of inflammatory biomarkers in this population. We conducted a systematic review assessing the predictive value of inflammatory biomarkers for major adverse ...
Ashley Murray, Niamh Louwman, Augustine Luk, Andrew Parker, Nomalanga Madyiwa, Harold Parker, Kathryn Woodward, Carola Fajardo Gallegos, Jienchi Dorward, Richard J. Stevens, Thomas R. Fanshawe   +10 more
wiley   +1 more source

Evaluation of suPAR Levels in Attention Deficit Hyperactivity Disorder Etiopathogenesis

Erciyes Medical Journal, 2019
Objective: Although a strong inflammatory basis has been demonstrated, the pathophysiology of attention deficit hyperactivity disorder (ADHD) has not been defined clearly.
Ayşe Irmak, Sevgi Özmen, Zeynep Şan, Esra Demirci   +3 more
doaj   +1 more source

Soluble urokinase plasminogen activator receptor and interleukin-6 improves prediction of all-cause mortality and major adverse cardiovascular events in Type 1 diabetes. [PDF]

J Intern Med
Abstract Background Type 1 diabetes (T1D) increases premature mortality risk, with cardiovascular disease being the leading cause. Chronic inflammation may play a role. Associations between inflammatory biomarkers and mortality are not well‐known in T1D.
Bahrami HSZ, Jørgensen PG, Hove JD, Dixen U, Rasmussen LJH, Eugen-Olsen J, Rossing P, Jensen MT.   +7 more
europepmc   +2 more sources