Results 81 to 90 of about 5,026 (202)

Inflammatory Biomarkers Predicting Major Adverse Cardiovascular Events in People Living With HIV: A Systematic Review and Meta‐Analysis

Journal of the International AIDS Society, Volume 29, Issue 4, April 2026.
ABSTRACT Introduction Chronic inflammation is a unique contributor to cardiovascular disease (CVD) risk among people living with HIV, yet there is a lack of consensus on the predictive utility of inflammatory biomarkers in this population. We conducted a systematic review assessing the predictive value of inflammatory biomarkers for major adverse ...
Ashley Murray, Niamh Louwman, Augustine Luk, Andrew Parker, Nomalanga Madyiwa, Harold Parker, Kathryn Woodward, Carola Fajardo Gallegos, Jienchi Dorward, Richard J. Stevens, Thomas R. Fanshawe   +10 more
wiley   +1 more source

ROC-curves based on the prognostic index of inclusion suPAR, HIV status, gender, age and with (red line) or without (blue line) increased suPAR level at 1 month included in the model.

, 2013
ROC-curves based on the prognostic index of inclusion suPAR, HIV status, gender, age and with (red line) or without (blue line) increased suPAR level at 1 month included in the model.
Andreas Andersen (310001), Victor Francisco Gomes (310004), Maya Bonde Haaland (310005), Peter Aaby (52776), Jesper Eugen-Olsen (39433), Paulo Rabna (181066), Christian Wejse (181054), Ines Oliveira (4769682)   +7 more
core   +1 more source

Unchanged plasma levels of the soluble urokinase plasminogen activator receptor in elective coronary artery bypass graft surgery patients and cardiopulmonary bypass use. [PDF]

PLoS ONE, 2014
Objective and designThe soluble urokinase plasminogen activator receptor (suPAR) has been recently recognized as a potential biological marker of various disease states, but the impact of a major surgical intervention on the suPAR level has not yet been ...
Waldemar Gozdzik, Barbara Adamik, Anna Gozdzik, Maciej Rachwalik, Wojciech Kustrzycki, Andrzej Kübler   +5 more
doaj   +1 more source

Plasma Proteomic Profiling of Young and Older Adults Identifies Candidate Biomarkers of Biological Aging at the Intersection of Age and Disease

Aging Cell, Volume 25, Issue 4, April 2026.
By comparing plasma proteomes of young and older adults, as well as older adults with varying levels of disease burden, this study aims to identify plasma proteins at the intersection of age and disease. The identified signature points to potential candidate biomarkers of biological aging.
Juliette Tavenier, Nikolaj Normann Holm, Thomas Kallemose, Morten Baltzer Houlind, Aino Leegaard Andersen, Line Fleischer Hach, Magnus Berglind, Ove Andersen, Jan O. Nehlin, Line Jee Hartmann Rasmussen   +9 more
wiley   +1 more source

Plasma suPAR is lowered by smoking cessation:a randomized controlled study

, 2016
BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) is a stable inflammatory biomarker. In patients, suPAR is a marker of disease presence, severity and prognosis.
Sørensen, Lars Tue, Ladelund, Steen, Eugen-Olsen, Jesper   +2 more
core   +1 more source

suPAR as a marker of infection in acute kidney injury – a prospective observational study

BMC Nephrology, 2018
Background Soluble urokinase-type plasminogen activator receptor (suPAR) has emerged as a new sepsis biomarker. It is not known whether suPAR has a role in critically ill patients with severe acute kidney injury (AKI).
Anna Hall, Siobhan Crichton, Matt Varrier, Danielle E. Bear, Marlies Ostermann   +4 more
doaj   +1 more source

Patients' Attitudes Towards Deprescribing and Associations With Patient‐Related Factors Across Two Hospital Settings

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 4, April 2026.
ABSTRACT Medication deprescribing is a targeted strategy to reduce inappropriate polypharmacy. Patients in primary care settings have reported high willingness to discontinue medications, but this phenomenon is less well studied in hospital settings. In this explorative post hoc analysis of two previously described clinical trials, we assessed patients'
Louise Westberg Strejby Christensen, Iman El Gamah, Amina Osman Ismail Barre, Daniela Claudia Moga, Anissa Aharaz, Olivia Bornæs, Rikke Lundsgaard Nielsen, Aino Leegaard Andersen, Esben Iversen, Kim Peder Dalhoff, Ove Andersen, Helle Gybel Juul‐Larsen, Morten Baltzer Houlind   +12 more
wiley   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, Volume 59, Issue 4, Page 590-613, April 2026.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu, Rou Xue, Xiangwen Luo, Jiangnan Liao, Zongbo Zhang, Jinhai Deng, Teng Liu, Xin Li, Zhe‐Sheng Chen, Mingzhu Yin   +9 more
wiley   +1 more source

Predicting Mortality in African Americans With Type 2 Diabetes Mellitus: Soluble Urokinase Plasminogen Activator Receptor, Coronary Artery Calcium, and High‐Sensitivity C‐Reactive Protein

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundType 2 diabetes mellitus is a major risk factor for cardiovascular disease; however, outcomes in individual patients vary. Soluble urokinase plasminogen activator receptor (suPAR) is a bone marrow–derived signaling molecule associated with ...
Salim S. Hayek, Jasmin Divers, Mohamad Raad, Jianzhao Xu, Donald W. Bowden, Melissa Tracy, Jochen Reiser, Barry I. Freedman   +7 more
doaj   +1 more source