Results 81 to 90 of about 4,267 (203)

Bioinformatics Analysis of Persistent Dysregulated Expression of Genes Involved in HCV‐Induced Neurological Disorders and Liver Injuries After DAA Treatment Through Weighted Gene Co‐Expression Network Analysis

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims The molecular processes involved in the progression of neuropsychiatric and liver disorders in some patients who have achieved sustained virologic response after successful DAA treatment are still unclear. To understand these processes, we investigated alterations in the transcription patterns of genes associated with ...
Mohadeseh Zarei Ghobadi, Mohammad Amin Nooraniyan Esfehani, Shohreh Shahmahmoodi, Ahmad Nejati, Abolfazl Keshavarz, Katayoun Samimi‐Rad   +5 more
wiley   +1 more source

Relationship Between Soluble Urokinase Plasminogen Activator Receptor (suPAR) and Disease Outcome in Adult-Onset Asthma

, 2022
BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) has emerged as a novel biomarker for various inflammatory conditions and has been proposed to associate with the severity of asthma. However, the relationship between suPAR and clinical
Kankaanranta, Hannu, Loponen, Juho, Hämäläinen, Mari, Hamalainen, M., Moilanen, E., Moilanen, Eeva, Niemelä, Taito, Ilmarinen, Pinja, Niemela, O., Loponen, J., Tuomisto, Leena E, Kankaanranta, Hannu,, Vahatalo, I., Niemelä, Onni, Tuomisto, Leena E., Vähätalo, Iida, Ilmarinen, P., Niemela, T., Tuomisto, L. E.   +18 more
core   +1 more source

Unchanged plasma levels of the soluble urokinase plasminogen activator receptor in elective coronary artery bypass graft surgery patients and cardiopulmonary bypass use. [PDF]

PLoS ONE, 2014
Objective and designThe soluble urokinase plasminogen activator receptor (suPAR) has been recently recognized as a potential biological marker of various disease states, but the impact of a major surgical intervention on the suPAR level has not yet been ...
Waldemar Gozdzik, Barbara Adamik, Anna Gozdzik, Maciej Rachwalik, Wojciech Kustrzycki, Andrzej Kübler   +5 more
doaj   +1 more source

TRPC6 effects on albumin permeation, nephrin shedding, and apoptosis in podocytes: Role of calcineurin and metalloproteases

Physiological Reports, Volume 13, Issue 21, November 2025.
Certain ligands of pattern recognition receptors can induce a rapid increase in albumin permeability across a podocyte monolayer that can be seen in 1 h, but activation of TRPC6 for up to 24 h does not mimick this process. However, continuous TRPC6 activation for 24 h results in nephrin ectodomain shedding that calcineurin activation and ...
Eun Young Kim, Stuart E. Dryer
wiley   +1 more source

Plasma suPAR is lowered by smoking cessation:a randomized controlled study

, 2016
BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) is a stable inflammatory biomarker. In patients, suPAR is a marker of disease presence, severity and prognosis.
Sørensen, Lars Tue, Ladelund, Steen, Eugen-Olsen, Jesper   +2 more
core   +1 more source

SuPAR mediates viral response proteinuria by rapidly changing podocyte function

, 2023
Elevation in soluble urokinase receptor (suPAR) and proteinuria are common signs in patients with moderate to severe coronavirus disease 2019 (COVID-19). Here we characterize a new type of proteinuria originating as part of a viral response.
Kwi Hye Koh, Salim S. Hayek, Jay Rappaport, David Cimbaluk, Nicholas W. Kriho, Changli Wei, Sudhini Yashwanth, Michigan Medicine COVID−19 Investigators, Tracy Fischer, Jing Li, Anis Ismail, Jochen Reiser, Alan Landay, Kyle T. Amber, Nicole Endlich, Shengyuan Luo, Prasun K. Datta, Florian Siegerist   +17 more
core   +1 more source

Predicting Mortality in African Americans With Type 2 Diabetes Mellitus: Soluble Urokinase Plasminogen Activator Receptor, Coronary Artery Calcium, and High‐Sensitivity C‐Reactive Protein

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundType 2 diabetes mellitus is a major risk factor for cardiovascular disease; however, outcomes in individual patients vary. Soluble urokinase plasminogen activator receptor (suPAR) is a bone marrow–derived signaling molecule associated with ...
Salim S. Hayek, Jasmin Divers, Mohamad Raad, Jianzhao Xu, Donald W. Bowden, Melissa Tracy, Jochen Reiser, Barry I. Freedman   +7 more
doaj   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu, Jia Yan, Yuyan Zhang, Xiaozhi Ming, Siqi Chen, Zhichao Zou, Nianjie Feng, Jianbo Xiao   +7 more
wiley   +1 more source

Prognostic value of suPAR and hs-CRP on cardiovascular disease

, 2018
Background and aims: Studies have shown that soluble urokinase Plasminogen Activator Receptor (suPAR) and CRP (both inflammatory markers) and coronary artery calcification (CAC) are independent risk predictors for cardiovascular (CV) disease.
Flemming Hald Steffensen, Niels Peter Rønnow Sand, Axel Diederichsen, Mickley, Hans, Grønhøj, Mette Hjortdal, Michael Hecht Olsen, Diederichsen, Axel; id_orcid, Diederichsen, Marie Zöga, Lambrechtsen, Jess; id_orcid, Diederichsen, Søren Zöga, Sand, Niels Peter Rønnow, Olsen, Michael Hecht, Steffensen, Flemming Hald, Hans Mickley, Kent Lodberg Christensen, Christensen, Kent Lodberg, Marie Zöga Diederichsen, Jess Lambrechtsen, Søren Zöga Diederichsen, Mette Hjortdal Grønhøj   +19 more
core   +1 more source

Inter‐Nanopartikel FRET für die Biosensorik: Photophysik versus Größe

Angewandte Chemie, Volume 137, Issue 39, September 22, 2025.
FRET‐Systeme mit lumineszierenden Nanopartikeln als Donoren und Akzeptoren (inter‐NP‐FRET) kombinieren einzigartige photophysikalische Eigenschaften mit großen Abmessungen. In diesem Aufsatz wird der Einfluss des NP‐Typs, der Architektur, der Oberflächenchemie und der optischen Eigenschaften auf FRET sowie die Vor‐ und Nachteile von inter‐NP FRET für ...
Eduard Madirov, Clara Catros, Niko Hildebrandt, Chloé Grazon   +3 more
wiley   +1 more source