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Refractory and Super-Refractory Status Epilepticus—an Update

Current Neurology and Neuroscience Reports, 2014
Status epilepticus is a medical emergency with a high mortality. Early recognition and initiation of treatment leads to a better response and may improve outcomes. Refractory status epilepticus is defined as recurrent seizure activity despite two appropriately selected and dosed antiepileptic drugs including a benzodiazepine. The term "super-refractory
Sara Hocker   +2 more
exaly   +3 more sources

Treatment options in pediatric super-refractory status epilepticus

Brain and Development, 2019
Super-refractory status epilepticus (SRSE) is a seizure that continues >24 h after anesthesia, or recurs on the reduction of anesthesia. SRSE is extremely difficult-to-control and associated with poor outcome. To date, optimal therapy and outcome data in children is limited.To assess etiology, treatment options and outcome in pediatric SRSE patients.We
Palita, Arayakarnkul   +1 more
exaly   +3 more sources

Neuromodulation in Super-refractory Status Epilepticus

Journal of Clinical Neurophysiology, 2021
Summary: Status epilepticus (SE) is a severe condition that needs immediate pharmacological treatment to tackle brain damage and related side effects. In approximately 20% of cases, the standard treatment for SE does not control seizures, and the condition evolves to refractory SE.
Ioannis, Stavropoulos   +2 more
openaire   +2 more sources

Management of Status Epilepticus, Refractory Status Epilepticus, and Super-refractory Status Epilepticus

Continuum, 2022
Status epilepticus is a serious condition caused by disorders and diseases that affect the central nervous system. In status epilepticus, hypersynchronous epileptic activity lasts longer than the usual duration of isolated self-limited seizures (time t1), which causes neuronal damage or alteration of neuronal networks at a certain time point (time t2),
Eugen, Trinka, Markus, Leitinger
openaire   +2 more sources

Super-Refractory Status Epilepticus

Current Neurology and Neuroscience Reports, 2015
Although the vast majority of patients with status epilepticus (SE) respond fairly well to the first- or second-line anti-epileptics, a minority require anesthetic agents to put the seizures under control. An even smaller number of patients do not even respond to those and constitute the subgroup of super-refractory SE.
Mauricio Ruiz, Cuero   +1 more
openaire   +3 more sources

Status Epilepticus, Refractory Status Epilepticus, and Super-refractory Status Epilepticus

Continuum, 2018
Status epilepticus, refractory status epilepticus, and super-refractory status epilepticus can be life-threatening conditions. This article presents an overview of the three conditions and discusses their management and outcomes.Status epilepticus was previously defined as lasting for 30 minutes or longer but now is more often defined as lasting 5 ...
Sarah E, Nelson, Panayiotis N, Varelas
openaire   +2 more sources

Status epilepticus: Refractory and super-refractory

Neurology India, 2017
Status epilepticus (SE) is an important neurological emergency. It is defined as seizures lasting for 5 minutes or more or recurrent seizures without recovery of consciousness to baseline between the attacks. Refractory SE (RSE) is defined as SE persisting despite sufficient dose of benzodiazepines and at least one antiepileptic drug (AED ...
Deepanshu, Dubey   +2 more
openaire   +2 more sources

Predictors of outcome in super refractory status epilepticus

Epilepsy & Behavior, 2021
We conducted this study to determine the clinical, electrophysiological and radiological predictors of outcome in Super Refractory Status Epilepticus (SRSE).Data of patients treated for SRSE between January 2000 and November 2019, archived prospectively in our SE registry were analyzed.
Jithu Jose   +6 more
openaire   +2 more sources

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