Formulation and development of orodispersible sustained release tablet of domperidone [PDF]
, 2016 Commercially available domperidone orodispersible tablets (ODT) are intended for immediate release of the drug, but none of them have been formulated for sustained action.
Patil, Hemlata +3 more
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Synthesis of MCC–PEG Conjugate and Its Evaluation as a Superdisintegrant [PDF]
AAPS PharmSciTech, 2010 PEGylated conjugate of microcrystalline cellulose (MCC) was synthesized by reacting MCC with polyethylene glycol (PEG) 200 in the presence of catalyst at elevated temperature. Conjugation between MCC and PEG was confirmed by FT-IR and (1)H NMR studies.
Mangesh R, Bhalekar +2 more
openaire +2 more sources
Application of SeDeM expert systems in preformulation studies of pediatric ibuprofen ODT tablets
Acta Pharmaceutica, 2017 Pediatric, ibuprofen containing orodispersible tablets (ODTs) were prepared using the SeDeM expert system methodology. In order to facilitate formulation, directly compressible ibuprofen was employed (Ibuprofen DC 8TM) and characterized using its SeDeM ...
Sipos Emese +4 more
doaj +1 more source
Novel polyvinylpyrrolidones to improve delivery of poorly-water soluble drugs; from design to synthesis and evaluation [PDF]
, 2012 Polyvinylpyrrolidone is a widely used in tablet formulations with the linear form acting as a wetting agent and disintegrant whereas the cross-linked form is a super-disintegrant.
Chappell, David +7 more
core +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2019 Flurbiprofen belongs to Biopharmaceutical Classification System (BCS) class II drugs which are poorly soluble in water. The objective of present research work was to prepare fast dissolving tablets of Flurbiprofen using varying concentrations of three ...
Nabeela Shaheen, Shahiq uz Zaman
doaj +1 more source
Liqui-pellet: the emerging next-generation oral dosage form which stems from liquisolid concept in combination with pelletization technology [PDF]
, 2019 In spite of the major advantages that the liquisolid technology offers, particularly in tackling poor bioavailability of poorly water-soluble drugs (i.e., BCS Class II drugs), there are a few critical drawbacks. The inability of a high liquid load factor,
Ghafourian, Taravat +2 more
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Mimicking the impact of infant tongue peristalsis on behaviour of solid oral dosage forms administered during breastfeeding [PDF]
, 2017 An in vitro simulation system was developed to study the effect of an infant’s peristaltic tongue motion during breastfeeding on oral rapidly disintegrating tablets in the mouth, for use in rapid product candidate screening.
Gerrard, SE +4 more
core
Evaluation of synthesized cross linked polyvinyl alcohol as potential disintegrant [PDF]
, 2010 Purpose: The present study deals with evaluation of crosslinked poly vinyl alcohol (PVA) as a potential disintegrant. Methods: Crosslinking of PVA was carried out using glutaraldehyde as a crosslinker, in presence of acidic conditions.
Patel, Ashok, Vavia, Pradeep R
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Majalah Obat Tradisional, 2018 Averrhoa bilimbi L. leaves can be used as an antidiabetic in the presence of flavonoid. Antidiabetic drugs were widely consumed by elderly patients who often had difficulty in consuming conventional tablets.
Citra Ariani Edityaningrum +3 more
doaj +1 more source
SYNTHESIS AND CHARACTERIZATION OF STARCH MALONATE: DEVELOPMENT OF FAST DISSOLVING TABLETS OF ACECLOFENAC BY 23 FACTORIAL DESIGNS [PDF]
, 2021 Objective: The aim of the research work is to develop a new superdisintegrant (starch malonate) which can help in enhancing the solubility and drug dissolution of poorly soluble drugs.
KUMAR, R. SANTOSH, KUMARI, ANNU
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