Formulation and Characterisation of Carbamazepine Orodispersible 3D-Printed Mini-Tablets for Paediatric Use [PDF]
One of the main challenges to paediatric drug administration is swallowing difficulties, hindering the acceptability of the medicine and hence clinical outcomes.
Jiayu Hu +3 more
doaj +2 more sources
Development and Evaluation of 3D-Printed Losartan Potassium Tablets Using Semi-Solid Extrusion: The Effect of Geometry, Drug Loading and Superdisintegrant [PDF]
Background/Objectives: Semi-solid extrusion (SSE) three-dimensional (3D) printing offers a versatile approach for fabricating personalized oral dosage forms. This study aimed to develop and optimize losartan potassium tablets produced via SSE 3D printing,
Aleksandra Vojinović +6 more
doaj +2 more sources
Psyllium (Plantago Ovata Forsk) Husk Powder as a Natural Superdisintegrant for Orodispersible Formulations: A Study on Meloxicam Tablets [PDF]
(1) Background: In this work, we investigated the application of a natural superdisintegrant, psyllium (Plantago ovata Forsk) husk powder, for the manufacture of orodispersible meloxicam tablets. Meloxicam was chosen as a model compound for the study. (2)
Gailute Draksiene +3 more
doaj +2 more sources
Formulation and evaluation of orally disintegrating tablet of Rizatriptan using natural superdisintegrant [PDF]
Introduction: Rizatriptan benzoate is a potent and selective 5-HT1B/1D receptor agonist and is effective for the treatment of acute migraine. Difficulty in swallowing is common among all age groups, especially elderly and pediatrics.
Tabbakhian Majid +3 more
doaj +3 more sources
Enhancing the Low Oral Bioavailability of Sulpiride via Fast Orally Disintegrating Tablets: Formulation, Optimization and In Vivo Characterization [PDF]
Sulpiride (SUL) is a dopamine D2-receptor antagonist used for management of GIT disturbance and it has anti-psychotic activities based on the administered dose.
Hesham M. Tawfeek +3 more
doaj +2 more sources
Revolutionizing fast disintegrating tablets: Harnessing a dual approach with porous starch and sublimation technique [PDF]
This study investigates the transformation of neat starch (NS) from mung beans into porous starch (PS) for the formulation of fast-disintegrating tablets (FDTs) using the sublimation technique, contrasting their performance with superdisintegrants such ...
Sameer J. Nadaf +4 more
doaj +2 more sources
Formulation of sublingual promethazine hydrochloride tablets for rapid relief of motion sickness [PDF]
The delivery of antihistaminic agents via the oral route is problematic, especially for elderly patients. This study aimed to develop a sublingual formulation of promethazine hydrochloride by direct compression, and to mask its intensely bitter taste ...
Hamad S Alyami +7 more
doaj +2 more sources
Directly Compressed Tablets of Free Acid Ibuprofen with Nanocellulose Featuring Enhanced Dissolution: A Side-by-Side Comparison with Commercial Oral Dosage Forms [PDF]
We have previously reported that heated powder mixtures of ibuprofen (IBU) and high surface area nanocellulose exhibit an enhanced dissolution and solubility of the drug due to IBU amorphization.
Athanasios Mantas +2 more
doaj +2 more sources
Superdisintegrant Selection for Tramadol Dispersible Tablets
The selection of a suitable superdisintegrant for a rapidly disintegrating dosage form is of the utmost importance, since disintegration time (DT) is a critical parameter.
Swati C. Jagdale +3 more
doaj +1 more source
Pediatric Orally Disintegrating Tablets (ODTs) with Enhanced Palatability Based on Propranolol HCl Coground with Hydroxypropyl-β-Cyclodextrin [PDF]
Background: Propranolol, largely prescribed as an antihypertensive and antiarrhythmic drug in pediatrics, is characterized by a bitter taste and an astringent aftertaste. Currently, the therapy requires crushing of tablets for adults and their dispersion
Marzia Cirri +4 more
doaj +2 more sources

