Results 11 to 20 of about 1,751 (191)

Formulation and Characterisation of Carbamazepine Orodispersible 3D-Printed Mini-Tablets for Paediatric Use [PDF]

open access: yesPharmaceutics, 2023
One of the main challenges to paediatric drug administration is swallowing difficulties, hindering the acceptability of the medicine and hence clinical outcomes.
Jiayu Hu   +3 more
doaj   +2 more sources

Development and Evaluation of 3D-Printed Losartan Potassium Tablets Using Semi-Solid Extrusion: The Effect of Geometry, Drug Loading and Superdisintegrant [PDF]

open access: yesPharmaceuticals
Background/Objectives: Semi-solid extrusion (SSE) three-dimensional (3D) printing offers a versatile approach for fabricating personalized oral dosage forms. This study aimed to develop and optimize losartan potassium tablets produced via SSE 3D printing,
Aleksandra Vojinović   +6 more
doaj   +2 more sources

Psyllium (Plantago Ovata Forsk) Husk Powder as a Natural Superdisintegrant for Orodispersible Formulations: A Study on Meloxicam Tablets [PDF]

open access: yesMolecules, 2019
(1) Background: In this work, we investigated the application of a natural superdisintegrant, psyllium (Plantago ovata Forsk) husk powder, for the manufacture of orodispersible meloxicam tablets. Meloxicam was chosen as a model compound for the study. (2)
Gailute Draksiene   +3 more
doaj   +2 more sources

Formulation and evaluation of orally disintegrating tablet of Rizatriptan using natural superdisintegrant [PDF]

open access: yesJournal of HerbMed Pharmacology, 2014
Introduction: Rizatriptan benzoate is a potent and selective 5-HT1B/1D receptor agonist and is effective for the treatment of acute migraine. Difficulty in swallowing is common among all age groups, especially elderly and pediatrics.
Tabbakhian Majid   +3 more
doaj   +3 more sources

Enhancing the Low Oral Bioavailability of Sulpiride via Fast Orally Disintegrating Tablets: Formulation, Optimization and In Vivo Characterization [PDF]

open access: yesPharmaceuticals, 2020
Sulpiride (SUL) is a dopamine D2-receptor antagonist used for management of GIT disturbance and it has anti-psychotic activities based on the administered dose.
Hesham M. Tawfeek   +3 more
doaj   +2 more sources

Revolutionizing fast disintegrating tablets: Harnessing a dual approach with porous starch and sublimation technique [PDF]

open access: yesHeliyon
This study investigates the transformation of neat starch (NS) from mung beans into porous starch (PS) for the formulation of fast-disintegrating tablets (FDTs) using the sublimation technique, contrasting their performance with superdisintegrants such ...
Sameer J. Nadaf   +4 more
doaj   +2 more sources

Formulation of sublingual promethazine hydrochloride tablets for rapid relief of motion sickness [PDF]

open access: yesSaudi Pharmaceutical Journal, 2021
The delivery of antihistaminic agents via the oral route is problematic, especially for elderly patients. This study aimed to develop a sublingual formulation of promethazine hydrochloride by direct compression, and to mask its intensely bitter taste ...
Hamad S Alyami   +7 more
doaj   +2 more sources

Directly Compressed Tablets of Free Acid Ibuprofen with Nanocellulose Featuring Enhanced Dissolution: A Side-by-Side Comparison with Commercial Oral Dosage Forms [PDF]

open access: yesPharmaceutics, 2020
We have previously reported that heated powder mixtures of ibuprofen (IBU) and high surface area nanocellulose exhibit an enhanced dissolution and solubility of the drug due to IBU amorphization.
Athanasios Mantas   +2 more
doaj   +2 more sources

Superdisintegrant Selection for Tramadol Dispersible Tablets

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2010
The selection of a suitable superdisintegrant for a rapidly disintegrating dosage form is of the utmost importance, since disintegration time (DT) is a critical parameter.
Swati C. Jagdale   +3 more
doaj   +1 more source

Pediatric Orally Disintegrating Tablets (ODTs) with Enhanced Palatability Based on Propranolol HCl Coground with Hydroxypropyl-β-Cyclodextrin [PDF]

open access: yesPharmaceutics
Background: Propranolol, largely prescribed as an antihypertensive and antiarrhythmic drug in pediatrics, is characterized by a bitter taste and an astringent aftertaste. Currently, the therapy requires crushing of tablets for adults and their dispersion
Marzia Cirri   +4 more
doaj   +2 more sources

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