Results 21 to 30 of about 1,751 (191)
Optimization and evaluation of venlafaxine hydrochloride fast dissolving oral films [PDF]
Saudi Pharmaceutical Journal, 2020 Three factors, three levels (33) full factorial design was used to develop venlafaxine HCl fast dissolving oral films (FDOFs) to optimize the concentrations of the film forming polymer; hydroxypropyl methylcellulose HPMC (X1), superdisintegrant; sodium ...
Arwa Ibrahim Al-Mogherah +2 more
doaj +2 more sources
Development and Evaluation of an Orodispersible Tablet Formation for the Delivery of a Hydrophobic Drug. [PDF]
Adv Pharmacol Pharm SciOrodispersible tablet (ODT) is a promising avenue for drug delivery, offering a dosage form that can be disintegrated instantaneously in the mouth and released the drug that dissolves or disperses in the saliva without the addition of water. ODT can effectively boost the dissolution rate and consequently the bioavailability of several hydrophobic drugs.
Haddad R, Gardouh AR.
europepmc +2 more sources
Formulation of Ebastine Fast-Disintegrating Tablet Using Coprocessed Superdisintegrants and Evaluation of Quality Control Parameters. [PDF]
ScientificWorldJournal, 2022 Ebastine is a long‐acting, nonsedating, second‐generation antihistaminic drug that prevents histamine action, mainly in immediate hypersensitivity. This project was aimed to formulate and characterize orodispersible tablets of ebastine, utilizing different proportions of three disintegrants, namely crospovidone, sodium starch glycolate, and coprocessed
Dhakal B +8 more
europepmc +2 more sources
Superdisintegrants: Brief Review
Journal of Drug Delivery and Therapeutics, 2022 Oral disintegrating tablets are a new trend in novel drug delivery systems that have seen a surge in popularity in recent decades. To improve the efficacy of solid dosage forms, super disintegrants are used. This is accomplished by reducing the disintegration time, which improves the rate of drug dissolution. Disintegrants are substances or combination
D.N. Prasad, Dhruv Dev, Jasmine Dhiman
openaire +2 more sources
Journal of Applied Pharmaceutical Research, 2022 The objective of this study was to assess the efficacy of several taste-masking techniques and to study the impact of different formulation variables on the physicochemical properties of dispersible tablets containing Ranitidine as a model drug ...
Alaa Elawni +4 more
doaj +1 more source
Calcium Phosphate Microcapsules as Multifunctional Drug Delivery Devices
Advanced Functional Materials, Volume 33, Issue 38, September 19, 2023., 2023 Inorganic calcium phosphate microcapsules comprise a hollow cavity surrounded by a porous shell. The high porosity of the microcapsule, as demonstrated by a large water uptake capacity and intrusion volume, provides ample space for the encapsulation of drug substances.
Jonas Kost, Jörg Huwyler, Maxim Puchkov
wiley +1 more source
Review article: sodium starch glycolate as a super disintegrant
Journal of Contemporary Pharmacy, 2021 Sodium starch glycolate (SSG) is most widely used excipient in the field of pharmaceutical sciences. SSG is extensively used as a superdisintegrant in different drug formulations.
Aneela Manzoor
doaj +1 more source
Recent progress in orodispersible films‐mediated therapeutic applications: A review
MedComm – Biomaterials and Applications, Volume 2, Issue 2, June 2023., 2023 The current therapeutic applications of orodispersible films (ODFs) are delivered either locally or systemically for potential patients suffering from various diseases, including oral inflammation, cardiovascular diseases, pain disorders, nausea and vomiting, mood or mental disorders, erectile dysfunction and pulmonary diseases Abstract Orodispersible ...
Yu Tian +5 more
wiley +1 more source
Orally Disintegrating Tablet Formulation of Avicennia Fruit Ethanol Extract (Avicennia marina)
Journal of Food and Pharmaceutical Sciences, 2021 The fruit produced from Avicennia tree (in the form of ethanol extract) has the property of reducing blood glucose levels (oral antidiabetic mellitus) with an effective dose of 10 mg / 50 kg human body weight.
Ungsari Rizki Eka Purwanto +3 more
doaj +1 more source
Challenges and Proven Recommendations of Praziquantel Formulation
Journal of Clinical Pharmacy and Therapeutics, Volume 2023, Issue 1, 2023., 2023 Background. Schistosomiasis, ranked second to malaria as one of the crucial parasitic infections in the world, infects close to 240 million people as at 2019. Praziquantel, an oral anthelmintic, is the first‐line drug for the treatment of schistosomiasis. Although the drug is safe and effective, the formulated tablets come with some limitations such as
Deryl Nii Okantey Kuevi +4 more
wiley +1 more source