Results 31 to 40 of about 1,751 (191)

Palatable Levocetirizine Dihydrochloride Solid Dispersed Fast‐Dissolving Films: Formulation and In Vitro and In Vivo Characterization

The Scientific World Journal, Volume 2022, Issue 1, 2022., 2022
One of the most important issues for bitter‐tasting drugs such as levocetirizine dihydrochloride (LCD) is the production of palatable dosage forms. LCD also has a delayed onset of action following oral administration. In this study, solid dispersed fast‐dissolving films (FDFs) of LCD using the solvent casting method for oral application were prepared ...
Sana Saleh Al-Kubati, Muna Abdo Ahmed, Nasr A. Emad, Ho SoonMin   +3 more
wiley   +1 more source

[Retracted] Development of Atorvastatin Calcium Biloaded Capsules for Oral Administration of Hypercholesterolemia

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
The goal of this study was to develop atorvastatin (ATN) calcium biloaded, i.e., immediate release (IR) and sustained release (SR) capsules that would promote the quick onset of action and a better dissolution profile on both the IR and SR aspects. The IR granules were prepared by the wet granulation method, and an aqueous solubility study proved that ...
Chitra Karthikeyini Senthilvel, Kavitha Karuppaiyan, Ananth Pothumani, Ananthi Vedharethinam, Ancy Wilfred Jose, Jamal Moideen Muthu Mohamed, Mohamed El Sherbiny, Hasnaa Ali Ebrahim, Mohamed El Shafey, Minilu Dejene, Hiwa M. Ahmed   +10 more
wiley   +1 more source

Formulation and Quality Control of Orally Disintegrating Tablets (ODTs): Recent Advances and Perspectives

BioMed Research International, Volume 2021, Issue 1, 2021., 2021
Orally disintegrating tablets (ODTs) rapidly disintegrate or dissolve in the oral cavity without using water. Demand for ODTs has increased, and the field has overgrown in the pharmaceutical industry and academia. It is reported that ODTs have several advantages over other conventional tablets.
Mohammadali Poursharifi Ghourichay, Seyed Hossein Kiaie, Ali Nokhodchi, Yousef Javadzadeh, Nilufer Yuksel   +4 more
wiley   +1 more source

Development of Duloxetine Hydrochloride Tablets for Delayed and Complete Release Using Eudragit L 100

International Journal of Polymer Science, Volume 2021, Issue 1, 2021., 2021
The purpose of the research was to optimize the preparation of duloxetine hydrochloride (duloxetine HCl) delayed release tablets. Duloxetine HCl produces a toxic substance called alpha‐naphthol when duloxetine HCl is in contact with gastric fluid. Thus, duloxetine HCl when given orally needed a protective enteric coating that disable the delivery of ...
M. Yasmin Begum, Ali Alqahtani, Mohammed Ghazwani, Noura Abdullah Alhamood, Umme Hani, Avanthi Jajala, Mohamed Rahamathulla, Qinglin Wu   +7 more
wiley   +1 more source

Formulation and development of Serratiopeptidase enteric coated tablets and analytical method validation by UV Spectroscopy

International Journal of Analytical Chemistry, Volume 2021, Issue 1, 2021., 2021
Serratiopeptidase (SRP) is a proteolytic enzyme that emerged as one of the most potent anti‐inflammatory and analgesic drugs. The purpose of the present study was to formulate and evaluate enteric‐coated tablets for SRP and investigate their stability using a simple and validated analytical method by ultraviolet (UV) spectroscopy. The colloidal silicon
Vijay Kumar Panthi, Saurav Kumar Jha, Raghvendra Chaubey, Rudra Pangeni, Adil Denizli   +4 more
wiley   +1 more source

SUPERDISINTEGRANT ON DISINTEGRANT AND DISSOLUTION

The Professional Medical Journal, 2016
In tablet formulation superdisintegrants are added to accelerate the rate of tabletdeaggregation and thus enhancing the rate of tablet dissolution. In this review article we gatherthe information related to the superdisintegrants, their mechanism of actions and their impacton disintegration and dissolution processes.
Muhammad Saquib Qureshi, Farya Zafar, Huma Ali, Kamran Hameed, Neelam Mallick, Sohail Khan, Saba Ajaz Baloch   +6 more
openaire   +3 more sources

Comparison of Co-Processed Superdisintegrants with Superdisintegrants in Drug Release for Palatable Fast Disintegrating Oral Films of Metolazone

Journal of Drug Delivery and Therapeutics, 2023
The present study was aimed to compare co-proceesed superdisentigrant with superdisentigrants in drug release and formulate a palatable fast disintegrating oral films of metolazone and compare with standard market solid oral dosage forms. The drug was incorporated as solid dispersion to mask the bitter taste of the drug with different polymers in ...
Shahid Mohammed, Aimen Fatima, Nabila Quraishi   +2 more
openaire   +1 more source

The effect of particle size on dissolution rate of fast dissolving oral film containing diclofenac sodium [PDF]

Pharmaciana, 2020
Diclofenac sodium is a Non-Steroidal Anti Inflammatory Drugs that if being taken orally have the side effects of peptic ulcers and undergone the first pass metabolism, and also included in the Biopharmaceutics Classification System class 2 which resulted
Fitrianti Darusman, Nyayu Ista Yulita, Gita Cahya Eka Darma   +2 more
doaj   +1 more source

Immediate release drug delivery systems: a current update

Journal of Applied Pharmaceutical Research, 2018
Instead of tremendous advancements in drug delivery, the oral route remains the most preferred route for the administration of therapeutic agents because of the low cost of therapy and ease of administration that leads to high levels of patient ...
Suman Saha
doaj   +1 more source

The effects of croscarmellose sodium concentration on the physicochemical characteristics of orodispersible tablets of atenolol [PDF]

, 2018
Hypertension is the most common cardiovascular diseases suffered by geriatric patients. Their physiological changes make the administration of conventional tablets less effective, especially regarding compliance.
Parfati, Nani, Rani, Karina Citra
core   +2 more sources