The influence of ethanol on superdisintegrants and on tablets disintegration
Disintegration of immediate release tablets originates from the volume expansion of disintegrants within the formulation. Here, we study the impact of ethanol on the disintegrant expansion and on tablets disintegration. The three most commonly used superdisintegrants, namely sodium starch glycolate (SSG), crospovidone (PVPP) and croscarmellose sodium ...
Lorina Bisharat +6 more
openaire +4 more sources
Efnodipine, a calcium channel blocker, is used for hypertension and angina pectoris. Efnodipine fast-disintegrating tablets (FDT) have been prepared by kneading method. In the present study cyclodextrins (?CD and HP?CD) and surfactants (Kolliphor HS15) were tried to enhance the solubility and dissolution rate of Efnodipine.
S.K. Sathish, V.P. Pandey
openaire +1 more source
FORMULASI SEDIAAN TABLET FAST DISENTEGRATING ANTASIDA DENGAN EXPLOTAB® SEBAGAI BAHAN PENGHANCUR DAN STARLAC® SEBAGAI BAHAN PENGISI [PDF]
Fast disintegrating tablet adalah salah satu bentuk sediaan tablet yang mudah pecah dalam rongga mulut tanpa bantuan air dari luar dan dapat hancur kurang dari 1 menit.
MARLITA, DEWI SARI
core
THE EFFECT OF COPROCESSED SUPERDISINTEGRANTS RATIO (CROSPOVIDONE-SODIUM STARCH GLYCOLATE) TO THE PHYSICOCHEMICAL CHARACTERISTICS OF ATENOLOL ORALLY DISINTEGRATING TABLETS [PDF]
Objective: The objective of this study was to evaluate the effect of coprocessed superdisintegrants (crospovidone-sodium starch glycolate) ratio 1:1; 1:2; and 1:3 to the physicochemical characteristics of atenolol orally disintegrating tablets. Methods:
., Meilany +2 more
core +1 more source
The aim of this investigation was to develop fast dissolving tablet of cinnarizine. A combination of super disintegrants, i.e., sodium starch glycolate (SSG) and crosscarmellose sodium (CCS) were used along with camphor as a subliming material.
Biswajit Basu +5 more
doaj +1 more source
OPTIMASI FORMULA TABLET EKSTRAK DAUN SAMBUNG NYAWA(Gynura procumbens (Lour.) Merr) DENGAN KOMBINASI BAHAN PENGIKAT NATRIUM KARBOKSIMETIL SELULOSA DAN BAHAN PENGHANCUR STARCH 1500 DENGAN METODE FACTORIAL DESIGN [PDF]
Daun sambung nyawa (Gynura procumbens (Lour.) Merr) adalah salah satu tanaman yang berkhasiat sebagai antikanker. Penggunaan daun sambung nyawa dimasyarakat masih secara tradisional, sehingga perlu dikembangkan menjadi bentuk sediaan yang lebih stabil ...
JIHAN , JIHAN
core
Formulasi Tablet Ekstrak Kangkung Air (Ipomoea Aquatica F.) Dengan Variasi Kadar Amilum Manihot Sebagai Bahan Penghancur [PDF]
Ipomoea aquatica F. are plant that has a hypoglycemic effect. Ipomoea aquatica F. was formulated into tablet dosage forms to produce benefits in terms of practicality and accuracy of therapeutic doses.Disintegrant has effect to release the active ...
Khaidir, S. (Sutrisna) +2 more
core +1 more source
Impact of alternative solid state forms and specific surface area of high-dose, hydrophilic active pharmaceutical ingredients on tabletability [PDF]
YesIn order to investigate the effect of using different solid state forms and specific surface area (TBET) of active pharmaceutical ingredients on tabletability and dissolution performance, the mono- and dihydrated crystalline forms of ...
Abdul Jaleel O. W. +30 more
core +1 more source
Development of fast dispersible aceclofenac tablets: Effect of functionality of superdisintegrants
Aceclofenac, a non-steroidal antiinflammatory drug, is used for posttraumatic pain and rheumatoid arthritis. Aceclofenac fast-dispersible tablets have been prepared by direct compression method. Effect of superdisintegrants (such as, croscarmellose sodium, sodium starch glycolate and crospovidone) on wetting time, disintegration time, drug content, in ...
Setty, C. Mallikarjuna +3 more
openaire +3 more sources
Formulation and in vitro evaluation of mouth dissolving tablets of levosulpiride
Objective: The objective of this study was to formulate and optimize a mouth dissolving formulation of levosulpiride. Method: Levosulpiride mouth dissolving tablet having D2-dopamine receptor antagonistic activity were made by direct compression using ...
Irfan Sohail +5 more
doaj +1 more source

