Results 11 to 20 of about 346 (137)
Scientia Pharmaceutica, 2022 Telmisartan (Tel) is a potent antihypertensive drug with a very poor aqueous solubility, especially in pH ranging from 3 to 9 (i.e., biological fluids) that results in poor bioavailability.
Reem A. Aldeeb +5 more
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Cogent Medicine, 2020 Objective: Oral dispersible isoniazid 50 mg/pyridoxine 6.25 mg fixed-dose combination (FDC) tablets were formulated for Isoniazid Preventive Therapy in pediatrics weighing less than 5 kg.
M. W. Mwangi +5 more
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SUPERDISINTEGRANT ON DISINTEGRANT AND DISSOLUTION
The Professional Medical Journal, 2016 In tablet formulation superdisintegrants are added to accelerate the rate of tabletdeaggregation and thus enhancing the rate of tablet dissolution. In this review article we gatherthe information related to the superdisintegrants, their mechanism of actions and their impacton disintegration and dissolution processes.
Muhammad Saquib Qureshi +6 more
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Preparation and Evaluation of Oral Disintegrating Tablets of Ketoprofen by Dirct Compression
Iraqi Journal of Pharmaceutical Sciences, 2017 Ketoprofen is a non-steroidal anti-inflammatory (NSAID) drug with analgesic, anti-inflammatory, and antipyretic effects. It is widely used in the treatment of inflammation and pain associated with rheumatic disorders such as rheumatoid arthritis ...
Saddam J.Nasser +2 more
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Journal of Drug Delivery and Therapeutics, 2023 The present study was aimed to compare co-proceesed superdisentigrant with superdisentigrants in drug release and formulate a palatable fast disintegrating oral films of metolazone and compare with standard market solid oral dosage forms. The drug was incorporated as solid dispersion to mask the bitter taste of the drug with different polymers in ...
Shahid Mohammed +2 more
openaire +1 more source
Indian Journal of Health Sciences and Biomedical Research KLEU, 2016 Introduction: Paroxetine hydrochloride is used as the antidepressant drug of the selective serotonin reuptake inhibitor. It is used to treat depression resistant to other antidepressants, depression complicated by anxiety, panic disorder, obsessive ...
V G Jamakandi +4 more
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Formulation, optimization and evaluation of quick dispersible tablets of sumatriptan
Journal of Applied Pharmaceutical Research, 2019 The main objective of this study was to prepare quick dispersible tablets of drug sumatriptan succinate, which can rapidly disintegrate in the saliva using three different superdisintegrants that is, sodium starch glycolate, crospovidone, and ...
Pragya Baghel +4 more
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Recent Trends in developments of Superdisintegrants: An Overview
Journal of Drug Delivery and Therapeutics, 2022 Fast dissolving tablets are solid unit dosage forms that dissolve or disintegrate quickly in the mouth without using water. To provide this type of character in a dosage form, different excipients are required. Superdisintegrants are a class of novel agents that have emerged in recent years. Improving drug bioavailability in the pharmaceutical field is
D.N. Prasad, Dhruv Dev, Nisha Rani
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Polytechnic Journal, 2019 The buccal delivery is an attractive route to improve the clinical efficacy of ropinirole hydrochloride (RH) for the treatment of Parkinson and restless syndrome since this drug undergoes extensive first-pass effect, which has only 50% bioavailability ...
Shahla S. Smail +2 more
doaj +1 more source
Impact of superdisintegrants on efavirenz release from tablet formulations [PDF]
Acta Pharmaceutica, 2010 Efavirenz (EFV) tablets of different doses were prepared by a wet granulation process using different superdisintegrants such as crosscarmellose sodium (CCS), sodium starch glycollate (SSG) and crosspovidone (CP) to evaluate the role of different disintegrants on the in vitro release of EFV.
Yelchuri Vijaya, Rajesh +5 more
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