Results 21 to 30 of about 346 (137)
Role of Superdisintegrants in Rapid Dissolving Oral Films
International Journal of Pharmaceutical Sciences Review and Research, 2022 Rapid dissolving oral film is the most advanced solid oral drug delivery system, that dissolve or disintegrate with in few seconds once placed in mouth without taking water or chewing. Drug directly reaches into systemic circulation therefore avoids first pass metabolism so bioavailability of medication may be improved. Now a days most of the pediatric,
Shruthi BK +2 more
openaire +1 more source
Development and Evaluation of Ondansetron Orally Disintegrating Tablets
British Journal of Pharmacy, 2019 Orally disintegrating tablet (ODT) has number of advantages like faster onset of action, ease of administration, rapid disintegration and dissolution etc.
Bipin Pustake +3 more
doaj +1 more source
Iraqi Journal of Pharmaceutical Sciences, 2017 Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of musculo-skeletal and joint disorders. The problem with this drug is its poor solubility in water and hence poor bioavailability after oral administration.
Eman B. H. Al-Khedairy
doaj +3 more sources
Physicochemical interactions between drugs and superdisintegrants
Journal of Pharmacy and Pharmacology, 2008 Abstract We have evaluated the interactions between superdisintegrants and drugs with different physicochemical characteristics, which may affect the in-vivo absorption e.g. after mucosal administration. The binding of sodium salicylate, naproxen, methyl hydroxybenzoate (methylparaben), ethyl hydroxybenzoate (ethylparaben), propyl ...
Nelly, Fransén +3 more
openaire +2 more sources
Application of hydroxypropylated crosslinked starch from the grains of Oryza sativa L. as potential disintegrant in compressed solid dosage form. [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2022 Context: The modification of starch from the grains of NSICRc222 rice variety may provide a new material with enhanced disintegrating functionality in compressed solid dosage forms.
Elizabeth A. Pagtalunan +2 more
doaj
Formulation and development of paediatric orally disintegrating carbamazepine tablets
Saudi Pharmaceutical Journal, 2022 Carbamazepine is a medicine used to manage epilepsy and partial or tonic-clonic seizures. This study aimed at formulating and obtaining carbamazepine orodispersible tablets for paediatric use at a 50 mg dose, with a diameter not greater than 6 mm and a ...
R Canadell-Heredia +5 more
doaj +1 more source
Formulation and Optimization of Oral Fast Dissolving Prochloperazine Maleate Tablets
Iraqi Journal of Pharmaceutical Sciences, 2017 Prochloperazine maleate (PCM) is one of the most prescribed phenothiazine. The purpose of the present research was to develop fast dissolving tablets of PCM with β-cyclodextrin inclusion complex. Tablets prepared by wet granulation with sublimation and
Dua'a K. Ahmed, Balkis A. Kamal
doaj +1 more source
Overcoming Poor Solubility of Dimenhydrinate: Development, Optimization and Evaluation of Fast Dissolving Oral Film [PDF]
Advanced Pharmaceutical Bulletin, 2018 Purpose: To develop fast dissolving oral film to address vomiting and nausea in pediatric population. Methods: Oral films of Dimenhydrinate were prepared by solvent casting method by using hydroxypropylmethyl cellulose E5 (HPMC E5), polyethylene glycol ...
Yuvraj Govindrao Jadhav +2 more
doaj +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2014 Objective: To formulate diclofenac sodium as fast dissolving tablets (FDTs) using fenugreek gum as a natural superdisintegrant which also possess anti-inflammatory activity.
M. Uday Kumar, M. Kishore Babu
doaj +1 more source
SUPERDISINTEGRANTS- CURRENT APPROACH
Journal of Drug Delivery and Therapeutics, 2014 ABSTRACT The desire of improved palatability in orally administered products has prompted the development of numerous formulations with improved performance and acceptability. Orally disintegrating tablets are an emerging trend in novel drug delivery system and have received ever-increasing demand during the last few decades.
openaire +1 more source