Results 31 to 40 of about 346 (137)
Superdisintegrant: crucial elements for mouth dissolving tablets
Mouth dissolving tablets have gained more popularity among solid oral dosage forms. They perform better than conventional tablets because of its ease of administration and patient’s compliance. It facilitates water less administration and rapid onset of action. It also helps in improving oral bioavailability.
Annu Kumari, Rada Santosh Kumar
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Natural Superdisintegrants for the Formulation of Orally Disintegrating Tablets
Oral route is the most favoured and preferred route for the administration for most of the dosage forms because it offers so many advantages over other routes of administration. Sometimes the oral route is associated with a problem called dysphagia. This condition can be seen in a population of paediatric, geriatric, patients with neurological problems,
Femi Joseph, K. Premaletha
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Background: Orodispersible tablets or fast dissolving tablets dissolve or disintegrate immediately on the patients’ tongue or buccal mucosa. This drug delivery system is suitable for drugs undergoing high first pass metabolism.
Harshal Pawar +3 more
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Effect of Superdisintegrants on Dissolution of Cationic Drugs
The effects of selected superdisintegrants on the dissolution behavior of several cationic drugs with varying water solubility were evaluated. All formulations were made with fixed disintegrant concentration and equal drug load using a model formulation. Tablets were made by direct compression and were compressed to equal hardness.
J. Balasubramaniam +5 more
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The influence of ethanol on superdisintegrants and on tablets disintegration
Disintegration of immediate release tablets originates from the volume expansion of disintegrants within the formulation. Here, we study the impact of ethanol on the disintegrant expansion and on tablets disintegration. The three most commonly used superdisintegrants, namely sodium starch glycolate (SSG), crospovidone (PVPP) and croscarmellose sodium ...
Lorina Bisharat +6 more
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Efnodipine, a calcium channel blocker, is used for hypertension and angina pectoris. Efnodipine fast-disintegrating tablets (FDT) have been prepared by kneading method. In the present study cyclodextrins (?CD and HP?CD) and surfactants (Kolliphor HS15) were tried to enhance the solubility and dissolution rate of Efnodipine.
S.K. Sathish, V.P. Pandey
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Background Migraine a chronic neurological disorder is characterized by moderate to severe headache episodes. Sumatriptan succinate an FDA-approved treatment for migraine in adults has demonstrated efficacy. Meanwhile Feverfew with a
Swati Modgekar +3 more
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Development and evaluation of mosapride citrate orally disintegrating tablets for dogs
: The purpose of the study was to prepare orally disintegrating tablets (ODTs) of mosapride citrate for dogs with fast disintegration and low cost. The ODTs were developed by varying the components and the ratio of excipients. A direct compression method
Tingting Yi
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Development and evaluation of ofloxacin orally disintegrating tablets
Bitter taste of ofloxacin, a broad spectrum bactericidal agent, is masked and orally disintegrating tablets were formulated. The bitter taste is masked by forming complex between drug and weak cation exchange resins, Tulsion 335 and Indion 204. Effect of
Badrinath Pralhadrao Mohite +3 more
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Background: Fast disintegrating tablet (FDT) of ondansetron has better patient compliance as it is easy to swallow for the treatment of nausea and vomiting.
Asha Maharjan +4 more
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