Results 51 to 60 of about 346 (137)

Formulation and evaluation of gastro-retentive floating bilayer tablet for the treatment of hypertension

Heliyon, 2020
The paper aimed to progress an ideal gastro retentive drug delivery system intended for directing Losartan and Hydrochlorothiazide as a fixed-dose combination for anti-hypertensive therapy.
Balaji Maddiboyina, Mudavath Hanumanaik, Ramya Krishna Nakkala, Vikas Jhawat, Pinki Rawat, Aftab Alam, Ahmed I. Foudah, Majed M. Alrobaian, Rahul Shukla, Sima Singh, Prashant Kesharwani   +10 more
doaj   +1 more source

Formulation Development of Albendazole-Loaded Self-Microemulsifying Chewable Tablets to Enhance Dissolution and Bioavailability

Pharmaceutics, 2019
Albendazole is an anthelmintic agent with poor solubility and absorption. We developed a chewable tablet (200 mg drug equivalent), containing a self-microemulsifying drug delivery system (SMEDDS), with oral disintegrating properties.
Somchai Sawatdee, Apichart Atipairin, Attawadee Sae Yoon, Teerapol Srichana, Narumon Changsan, Tan Suwandecha   +5 more
doaj   +1 more source

Solubility enhancement, physicochemical characterization and formulation of fast-dissolving tablet of nifedipine-betacyclodextrin complexes

Brazilian Journal of Pharmaceutical Sciences, 2012
The main objective of the study was to enhance the dissolution of nifedipine, a poorly water soluble drug by betacyclodextrin complexation and to study the effect of the preparation method on the in vitro dissolution profile.
Swati Changdeo Jagdale, Vinayak Narhari Jadhav, Aniruddha Rajaram Chabukswar, Bhanudas Shankar Kuchekar   +3 more
doaj   +1 more source

A new design for a chronological release profile of etodolac from coated bilayer tablets: In-vitro and in-vivo assessment

Journal of Advanced Research, 2019
Repeated dose medication usually maximizes adverse effects, while sustained release systems did not offer a fast onset of action. Etodolac was formulated to enable pulsatile and sustained drug release, which was chronologically more suitable as an anti ...
Kirolos R. Georgy, Ragwa M. Farid, Randa Latif, Ehab R. Bendas   +3 more
doaj   +1 more source

Formulation and evaluation of orally disintegrating tablet of Rizatriptan using natural superdisintegrant [PDF]

Journal of HerbMed Pharmacology, 2014
Introduction: Rizatriptan benzoate is a potent and selective 5-HT1B/1D receptor agonist and is effective for the treatment of acute migraine. Difficulty in swallowing is common among all age groups, especially elderly and pediatrics.
Tabbakhian Majid, Shahtalebi Mohammad Ali, Salehi Ehsan, Keshvari Mahtab   +3 more
doaj  

Novel sublingual tablets of Atorvastatin calcium/Trimetazidine hydrochloride combination; HPTLC quantification, in vitro formulation and characterization

Saudi Pharmaceutical Journal, 2019
Background: Ischemic heart disorders and accumulation of lipids in blood vessels could contribute to angina pectoris. Therefore, the aim of this study was to formulate sublingual tablets containing a novel combination of Atorvastatin calcium (ATOR) and ...
Noha N. Atia, Hesham M. Tawfeek, Azza H. Rageh, Marwa R. El-Zahry, Ahmed Abdelfattah, Mahmoud A. Younis   +5 more
doaj   +1 more source

Development and evaluation of bilayer tablets of combination of antibiotics for the treatment of sexually transmitted disease

Brazilian Journal of Pharmaceutical Sciences
The present research work was envisaged to develop bilayer tablets to improve therapeutic efficacy of antibiotic combination for the treatment of sexually transmitted diseases. The combination of two antibiotics i.e.
Swati Sanjay Gaikwad, Sandip Annaji Chafle, Princy Sunil Morris, Jasmine Gev Avari   +3 more
doaj   +1 more source

Formulation and evaluation of orally disintegrating tablet of ondansetron using natural superdisintegrant [PDF]

Journal of HerbMed Pharmacology, 2015
Introduction: Difficulty in swallowing is common among all age groups, especially elderly and pediatrics. Orally disintegrating tablets may constitute an innovative dosage form that overcome the problem of swallowing and provide a quick onset of action ...
Shahtalebi Mohammad Ali, Tabbakhian Majid, Koosha Sina   +2 more
doaj  

Formulation and in vitro evaluation of fast dissolving tablets of metoprolol tartrate

Brazilian Journal of Pharmaceutical Sciences, 2013
The demand for fast dissolving tablets has been growing during the last decade, especially for elderly and children who have swallowing difficulties. In the present work, fast dissolving tablets of metoprolol tartrate, were prepared using sodium starch ...
Mangesh Machhindranath Satpute, Nagesh Shivaji Tour   +1 more
doaj   +1 more source

In Vitro/In Vivo Evaluation of Clomipramine Orodispersible Tablets for the Treatment of Depression and Obsessive-Compulsive Disorder. [PDF]

Pharmaceuticals (Basel), 2023
Ghumman SA, Hameed H, Noreen S, Al-Hussain SA, Kausar R, Irfan A, Shabbir R, Rana M, Amanat A, Zaki MEA.   +9 more
europepmc   +1 more source