Results 41 to 50 of about 4,805 (183)

Microvascular imaging of the unstained human superior colliculus using synchrotron-radiation phase-contrast microtomography

open access: yesScientific Reports, 2022
Characterizing the microvasculature of the human brain is critical to advance understanding of brain vascular function. Most methods rely on tissue staining and microscopy in two-dimensions, which pose several challenges to visualize the three ...
Ju Young Lee   +6 more
doaj   +1 more source

Electrical stimulation of the superior colliculus induces non- topographically organized perturbation of reaching movements in cats

open access: yesFrontiers in Systems Neuroscience, 2015
Besides its well-known contribution to orienting behaviors, the superior colliculus (SC) might also play a role in controlling visually-guided reaching movements.
Jean-Hubert eCourjon   +5 more
doaj   +1 more source

Did you choose appropriate tracer for retrograde tracing of retinal ganglion cells? The differences between cholera toxin subunit B and Fluorogold. [PDF]

open access: yesPLoS ONE, 2018
Cholera toxin subunit B (CTB) and Fluorogold(FG) are two widely utilized retrograde tracers to assess the number and function of retinal ganglion cells (RGCs).
Fei Yao   +5 more
doaj   +1 more source

Effects of ocular hypertension in the visual system of pigmented mice. [PDF]

open access: yesPLoS ONE, 2015
To study the effects of ocular hypertension (OHT) on the visual system of C57BL/6 pigmented mice, the limbal and episcleral veins of the left eye were laser photocoagulated (LP).
Francisco J Valiente-Soriano   +9 more
doaj   +1 more source

Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucoma

open access: yesFrontiers in Neuroscience, 2014
Axonal transport deficits have been reported as an early pathology in several neurodegenerative disorders, including glaucoma. However, the progression and mechanisms of these deficits are poorly understood.
Christine M Dengler-Crish   +8 more
doaj   +1 more source

Hydrocephalus caused by conditional ablation of the Pten or beta-catenin gene

open access: yesCerebrospinal Fluid Research, 2008
To investigate the roles of Pten and β-Catenin in the midbrain, either the Pten gene or the β-catenin gene was conditionally ablated, using Dmbx1 (diencephalon/mesencephalon-expressed brain homeobox gene 1)-Cre mice.
Ohtoshi Akihira
doaj   +1 more source

Deficits in the activation of human oculomotor nuclei in chronic traumatic brain injury

open access: yesFrontiers in Neurology, 2015
Binocular eye movements form a finely-tuned system that requires accurate coordination of the oculomotor dynamics of the brainstem control nuclei when tracking the fine binocular disparities required for 3D vision.
Christopher W Tyler   +3 more
doaj   +1 more source

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

open access: yesAnnals of Neurology, Volume 98, Issue 6, Page 1178-1195, December 2025.
[Color figure can be viewed at www.annalsofneurology.org] Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and ...
Nico J. Diederich   +20 more
wiley   +1 more source

Sex Differences in Auditory Brainstem Responses of Two Rat Models of Autism: Environmental and Genetic Contributions to Autism‐Like Auditory Function

open access: yesAutism Research, Volume 18, Issue 12, Page 2382-2408, December 2025.
ABSTRACT Autism is an early‐onset neurodevelopmental disorder characterized by restricted, repetitive behaviors and atypical patterns of social communication and interaction. A considerable proportion of autistic individuals experience divergent auditory perception, which can interfere with their ability to navigate everyday sound environments ...
Sara Cacciato‐Salcedo   +2 more
wiley   +1 more source

White matter volume loss drives cortical reshaping after thalamic infarcts

open access: yesNeuroImage: Clinical, 2022
Objective: The integration of somatosensory, ocular motor and vestibular signals is necessary for self-location in space and goal-directed action. We aimed to detect remote changes in the cerebral cortex after thalamic infarcts to reveal the thalamo ...
Julian Conrad   +12 more
doaj   +1 more source

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