Results 41 to 50 of about 19,360 (180)

Superior Colliculus: A Vision for Orienting [PDF]

open access: yesCurrent Biology, 2018
The superior colliculus contains neurons sensitive to motion direction. New research shows that these neurons are anatomically clustered: those representing the region of visual space 'seen' by both eyes preferentially respond to nasal motion directions and others to opposite directions.
openaire   +2 more sources

Superior sensation: superior colliculus participation in rat vibrissa system

open access: yesBMC Neuroscience, 2007
Background The superior colliculus, usually considered a visuomotor structure, is anatomically positioned to perform sensorimotor transformations in other modalities.
Hemelt Marie E, Keller Asaf
doaj   +1 more source

Superior Colliculus Control of Vibrissa Movements [PDF]

open access: yesJournal of Neurophysiology, 2008
This study tested the role of the superior colliculus in generating movements of the mystacial vibrissae—whisking. First, we compared the kinematics of whisking generated by the superior colliculus with those generated by the motor cortex. We found that in anesthetized rats, microstimulation of the colliculus evoked a sustained vibrissa protraction ...
Marie E, Hemelt, Asaf, Keller
openaire   +2 more sources

Exploring the Superior Colliculus In Vitro

open access: yesJournal of Neurophysiology, 2009
The superior colliculus plays an important role in the translation of sensory signals that encode the location of objects in space into motor signals that encode vectors of the shifts in gaze direction called saccades. Since the late 1990s, our two laboratories have been applying whole cell patch-clamp techniques to in vitro slice preparations of ...
Tadashi, Isa, William C, Hall
openaire   +3 more sources

Warning! Dopaminergic Modulation of the Superior Colliculus [PDF]

open access: yesTrends in Neurosciences, 2016
Recent work by Bolton et al. describes a dopaminergic input to the superior colliculus (SC) from the zona incerta, as well as the organization of D1- and D2-receptor expression in the SC. We discuss a potential role for this input in modulating SC-mediated behavior, particularly in response to aversive stimuli.
Jaclyn, Essig, Gidon, Felsen
openaire   +2 more sources

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

Cervical dystonia: a disorder of the midbrain network for covert attentional orienting.

open access: yesFrontiers in Neurology, 2014
While the pathogenesis of cervical dystonia remains unknown, recent animal and clinical experimental studies have indicated its probable mechanisms. Abnormal temporal discrimination is a mediational endophenotype of cervical dystonia and informs new ...
Michael eHutchinson   +18 more
doaj   +1 more source

Production of 3D printed biomodels of the canine brain for veterinary neuroanatomy teaching

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Teaching neuroanatomy presents multiple challenges to both students and teachers, as it is a subject with highly dense content that commonly causes the development of aversion by students, a phenomenon referred to as “neurophobia,” which has been documented in human and veterinary medicine students.
João Victor Barbosa Tenório Fireman   +1 more
wiley   +1 more source

Show Me the Brain!!: A modern approach to neuroanatomy education

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Show Me the Brain!! (SMtB) is a digital system for interactive graphics that is designed to support instruction in neuroanatomy and neuroscience. It will soon be made open‐source and freely available. SMtB bridges medical and traditional neuroanatomy instruction with the computational systems and representational conventions common in ...
Nicholas C. Hindy   +3 more
wiley   +1 more source

Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease

open access: yesNeurobiology of Disease, 2009
The triple transgenic mouse (3xTgAD), harboring human APPSwe, PS1M146V and TauP301L genes, develops age-dependent forebrain intraneuronal Aβ and tau as well as extraneuronal plaques.
Cassia R. Overk   +2 more
doaj   +1 more source

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