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Superoxide Dismutase Mimetics

Pulmonary Pharmacology & Therapeutics, 2002
In this review we describe the potential role(s) of superoxide in inflammatory disorders.
SALVEMINI D   +3 more
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Superoxide, Superoxide Dismutase and the Respiratory Burst

Veterinary Clinical Pathology, 1983
SummaryPhagocytes undergo a sharp burst of oxygen consumption when engulfing bacteria. This oxygen is enzymatically reduced to toxic metabolites which are essential to the bactericidal action of the cell. Oxygen metabolites formed in this burst as well as other intermediates formed in biological reduction reactions do not selectively reserve their ...
H S, Bender, W R, Chickering
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SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES

Annual Review of Biochemistry, 1972
O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH.. SODs inhibit such HO. production by scavengingO2-, but Cu, ZnSODs, by virtue of a nonspecific peroxidase activity, may peroxidize spin trapping agents and thus give the appearance of catalyzing OH ...
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