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Superoxide dismutases shape manganese stoichiometry in Southern Ocean diatoms
McCain JSP +8 more
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Pulmonary Pharmacology & Therapeutics, 2002
In this review we describe the potential role(s) of superoxide in inflammatory disorders.
SALVEMINI D +3 more
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In this review we describe the potential role(s) of superoxide in inflammatory disorders.
SALVEMINI D +3 more
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Superoxide, Superoxide Dismutase and the Respiratory Burst
Veterinary Clinical Pathology, 1983SummaryPhagocytes undergo a sharp burst of oxygen consumption when engulfing bacteria. This oxygen is enzymatically reduced to toxic metabolites which are essential to the bactericidal action of the cell. Oxygen metabolites formed in this burst as well as other intermediates formed in biological reduction reactions do not selectively reserve their ...
H S, Bender, W R, Chickering
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SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES
Annual Review of Biochemistry, 1972O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH.. SODs inhibit such HO. production by scavengingO2-, but Cu, ZnSODs, by virtue of a nonspecific peroxidase activity, may peroxidize spin trapping agents and thus give the appearance of catalyzing OH ...
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Engineered Superoxide Dismutase Monomers for Superoxide Biosensor Applications
Analytical Chemistry, 2005Because of its high reaction rate and specificity, the enzyme superoxide dismutase (SOD) offers great potential for the sensitive quantification of superoxide radicals in electrochemical biosensors. In this work, monomeric mutants of human Cu,Zn-SOD were engineered to contain one or two additional cysteine residues, which could be used to bind the ...
Beissenhirtz, Moritz Karl +3 more
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