Results 301 to 310 of about 735,827 (347)

Superoxide in the Vascular System

Journal of Vascular Research, 2002
Oxidant production and regulation is becoming increasingly important in the study of vascular signaling mechanisms, and recent reviews have characterized some of the possible roles for known downstream products of superoxide formation. In this review, we will examine current research in the field, with a special emphasis on the role of the superoxide ...
Sachin A. Gupte, Richard A. Oeckler, Michael S. Wolin   +2 more
openaire   +2 more sources

Reductive elimination of superoxide: Structure and mechanism of superoxide reductases

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2010
Superoxide anion is among the deleterious reactive oxygen species, towards which all organisms have specialized detoxifying enzymes. For quite a long time, superoxide elimination was thought to occur through its dismutation, catalyzed by Fe, Cu, and Mn or, as more recently discovered, by Ni-containing enzymes.
João V. Rodrigues, Miguel Teixeira, A.F. Pinto   +2 more
openaire   +3 more sources

Superoxide constitutes a major signal of mitochondrial superoxide flash

Life Sciences, 2013
Mitochondrial flashes detected with an N- and C-terminal circularly-permuted yellow fluorescent protein (cpYFP) have been thought to represent transient and quantal bursts of superoxide production under physiological, stressful and pathophysiological conditions.
Heping Cheng, Tao Ye, Zhanglong Huang, Yanru Wang, Jiejia Xu, Wei Shang, Xianhua Wang, Xing Zhang, Tingting Hou, Feng Gao   +9 more
openaire   +3 more sources

Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase.

Science, 1999
The copper chaperone for the superoxide dismutase (CCS) gene is necessary for expression of an active, copper-bound form of superoxide dismutase (SOD1) in vivo in spite of the high affinity of SOD1 for copper (dissociation constant = 6 fM) and the high ...
T. Rae, P. Schmidt, R. A. Pufahl, Valeria L Culotta, T. O’Halloran   +4 more
semanticscholar   +1 more source

Effect of aluminium on lipid peroxidation, superoxide dismutase, catalase, and peroxidase activities in root tips of soybean (Glycine max)

, 1991
Inhibition of root elongation and modification of membrane properties are sensitive responses of plants to aluminium. The present paper reports on the effect of AI on lipid peroxidation and activities of enzymes related to production of activated oxygen ...
I. Cakmak, W. Horst
semanticscholar   +1 more source

Development of superoxide sensor by superoxide dismutase immobilization

2001
In the present study, superoxide (O2) (one of reactive oxygen species) concentration was measured directly using a superoxide dismutase (SOD)-immobilized electrode. Using a batch cell, super-oxide production from oxidation of hypoxanthine with xanthine oxidase (XOD) was determined from current data.
Naoyuki Himi, Satoka Aoyagi, Seiichi Mochizuki, Takehiro Miyasaka, Kosuke Endo, Kiyotaka Sakai   +5 more
openaire   +2 more sources

Superoxide dismutase: improved assays and an assay applicable to acrylamide gels.

Analytical Biochemistry, 1971
C. Beauchamp, I. Fridovich
semanticscholar   +1 more source

Superoxidation of Bisretinoids

Angewandte Chemie International Edition, 2005
Steffen Jockusch, Koji Nakanishi, Ilyas Washington, Nicholas J. Turro, Yasuhiro Itagaki   +4 more
openaire   +3 more sources

Superoxide and the Superoxide Dismutases: An Introduction by Irwin Fridovich

2016
The univalent reduction of molecular oxygen to superoxide is the facile pathway for oxygen reduction because of the spin restriction facing its divalent reduction by pairs of spin-opposed electrons. The reactivity of superoxide, and of its conjugate acid the hydroperoxyl radical, threatens aerobic life.
openaire   +2 more sources

Superoxide Dismutases: Defence Against Endogenous Superoxide Radical

2008
Attempts to measure the rate of O2- production, in whole cells or in intact subcellular organelles, are frustrated by the endogenous superoxide dismutase (SOD). Streptococcus faecalis contains a single manganese-SOD which was isolated and used as an antigen in the rabbit. A precipitating and inhibiting antibody was obtained and used to suppress the SOD
openaire   +3 more sources