Results 301 to 310 of about 620,257 (337)
Some of the next articles are maybe not open access.
Parasitology Today, 1994
Eric James here discusses the molecular forms of superoxide dismutase and looks at its potential role in the pathogenesis of parasitic infections.
openaire +2 more sources
Eric James here discusses the molecular forms of superoxide dismutase and looks at its potential role in the pathogenesis of parasitic infections.
openaire +2 more sources
Extracellular superoxide dismutase
The International Journal of Biochemistry & Cell Biology, 2005The extracellular space is protected from oxidant stress by the antioxidant enzyme extracellular superoxide dismutase (EC-SOD), which is highly expressed in selected tissues including blood vessels, heart, lungs, kidney and placenta. EC-SOD contains a unique heparin-binding domain at its carboxy-terminus that establishes localization to the ...
Eva, Nozik-Grayck +2 more
openaire +2 more sources
Keratinocyte Superoxide Generation
Free Radical Biology and Medicine, 1998We have demonstrated using the reduction of cytochrome c, that the keratinocyte cell line H357 generates superoxide at significant rates (8.36 nmol/h/10[6] cells). The rate of superoxide release decreased as the cells reached confluence. Superoxide production was increased more than twofold following preincubation with IL-1beta, or by the addition of ...
Turner, CP, Toye, AM, Jones, OTG
openaire +2 more sources
The Journal of Physical Chemistry B, 2005
Density-functional calculations indicate that the second sphere of coordination around the metal centers of manganese and iron superoxide dismutases (MnSODs and FeSODs) plays an important role in the binding of O2(-). In these systems, O2(-) prefers to bind to Mn or Fe in end-on configurations. For human and E.
Isabel A, Abreu +2 more
openaire +2 more sources
Density-functional calculations indicate that the second sphere of coordination around the metal centers of manganese and iron superoxide dismutases (MnSODs and FeSODs) plays an important role in the binding of O2(-). In these systems, O2(-) prefers to bind to Mn or Fe in end-on configurations. For human and E.
Isabel A, Abreu +2 more
openaire +2 more sources
Superoxide, superoxide dismutase and ischemic injury.
Current opinion in investigational drugs (London, England : 2000), 2002Oxidative stress results from an oxidant/antioxidant imbalance: an excess of oxidants relative to the antioxidant capacity. Recent evidence strongly suggests that oxidant stress plays a major role in several aspects of ischemia and reperfusion. Immunohistochemical and biochemical evidence demonstrate the significant role of reactive oxygen species, in ...
Salvemini, Daniela, CUZZOCREA, Salvatore
openaire +2 more sources
Superoxidation of Retinoic Acid
Photochemistry and Photobiology, 2006Atmospheric pressure chemical ionization mass spectroscopy (APCI-MS) was used to examine the light-induced oxidation products of retinoic acid under conditions that favor and preclude its aggregation. We observed that in conditions that favor aggregation, i.e. in aqueous solutions, retinoic acid undergoes superoxidation to yield highly oxidized species.
Ilyas, Washington +2 more
openaire +2 more sources
Superoxide Dismutases: Defence Against Endogenous Superoxide Radical
2008Attempts to measure the rate of O2- production, in whole cells or in intact subcellular organelles, are frustrated by the endogenous superoxide dismutase (SOD). Streptococcus faecalis contains a single manganese-SOD which was isolated and used as an antigen in the rabbit. A precipitating and inhibiting antibody was obtained and used to suppress the SOD
openaire +2 more sources
Superoxide Dismutase Biosensors for Superoxide Radical Analysis
Analytical Letters, 1999ABSTRACT Some basic work has been performed on the development and optimisation of superoxide dismutase (SOD) biosensors for superoxide radical analysis. Initially we studied the possibility of obtaining a SOD biosensor using the Clark electrode as indicating sensor.
CAMPANELLA, Luigi +2 more
openaire +2 more sources
A superoxide dismutase-modified electrode that detects superoxide ion
Chemical Communications, 2002A superoxide dismutase (SOD)-modified electrode, in which SOD is oriented on the gold electrode via a self-assembled monolayer of cysteine so as to allow its direct electrode reaction, possesses a bi-directional electrocatalysis for both the oxidation of superoxide ion (O2-) to O2 and the reduction of O2- to H2O2 and functions as a third generation O2-
T.Ohsaka +4 more
openaire +2 more sources
Microplate Superoxide Dismutase Assay Employing a Nonenzymatic Superoxide Generator
Analytical Biochemistry, 1995The antioxidant enzyme superoxide dismutase (EC 1.15.1.1) (SOD) catalyzes the conversion of superoxide anion radical (O2.-) to hydrogen peroxide and molecular oxygen. SOD helps prevent tissue damage by O2.- and its metabolites, and augmentation of tissue SOD is a useful therapeutic strategy in certain diseases having an oxidative-injury component ...
J F, Ewing, D R, Janero
openaire +2 more sources