Results 91 to 100 of about 145,800 (349)

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun, XueBo Wei, ZhuoYang Song, JunJun Luo, JingYi Ye, YinNan Zhang, LiFei Zhu, Jie Gao, Hongyu Zhang, Hong Zhu, Xin Wang, Ke Xu   +11 more
wiley   +1 more source

Reaction of superoxide radicals with glycosaminoglycan chloramides: a kinetic study. [PDF]

, 2013
Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, perhaps through the binding of myeloperoxidase directly to the glycosaminoglycans.
A.W.J. Paterson, Adams, Al-Assaf, Al-Assaf, Aruoma, B.J. Parsons, Bielski, Butler, Camenisch, Chawla, D.J. Heyes, Daphna, Dogliotti, Figueroa, Hardingham, Hawkins, Hayon, Heckel, Heinecke, Ilan, Ivanov, Jiang, Johnson, Kennett, Kennett, Laurent, Laurent, McElroy, McElroy, McGowan, Milner, Misra, Neta, Parsons, Pattison, Pattison, Poskrebyshev, Redpath, Rees, Rees, Rees, Rees, Rees, S. Sibanda, Schwarz, Stern, Tang, Thomas, Thorne, Toole, Toole, Toole, Turley, Van Gelden, van Golen, Wine, Woods, Zao   +57 more
core   +1 more source

Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications

Advanced Materials, EarlyView.
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal, Majd Bisharat, Bassma Khamaisi, Krishanu Ghosal, Eid Nassar‐Marjiya, Qi Wu, Shadi Daoud, Idan Redenski, Samer Srouji, Shady Farah   +9 more
wiley   +1 more source

Mechanism research of type I reactive oxygen species conversion based on molecular and aggregate levels for tumor photodynamic therapy

Aggregate
Type I photosensitizers (PSs) with the ability to generate reactive oxygen species (ROS) containing superoxide anion and hydroxyl radical have promising application potential for treating hypoxia tumors, but the deep mechanism of type II ROS converts to ...
Youqin Xu, Yili Xie, Qing Wan, Jianwen Tian, Jing Liang, Jianlong Zhou, Mu Song, Xinke Zhou, Muzhou Teng   +8 more
doaj   +1 more source

Alterations in innate immune responses of patients with chronic rhinosinusitis related to cystic fibrosis.

PLoS ONE, 2022
The role of phagocytes of children with cystic fibrosis (CF) associated with different phenotypes of chronic rhinosinusitis (CRS) is unclear. The aim of this study was to evaluate the phagocytic capacity of blood neutrophils and monocytes and production ...
Gustavo L Rezende, Marcio Nakanishi, Shirley C P Couto, Carmen L F S Martins, André L L Sampaio, Lucas F F Albuquerque, Selma A S Kückelhaus, Maria I Muniz-Junqueira   +7 more
doaj   +1 more source

Microvascular alterations in hypertension and vascular aging [PDF]

, 2017
Hypertension and aging are characterized by vascular remodelling and stiffness as well as endothelial dysfunction. Endothelial function declines with age, since aging is associated with senescence of the endothelium due to increased rate of apoptosis and
Battistoni, Allegra, Calvez, Valentin, Cesario, Vincenzo, Filippini, Antonio, Montefusco, G, Savoia, Carmine   +5 more
core   +1 more source

Hypercholesterolemia increases endothelial superoxide anion production. [PDF]

Journal of Clinical Investigation, 1993
Indirect evidence suggests accelerated degradation of endothelium-derived nitric oxide (ENDO) by superoxide anion (O2-) in hypercholesterolemic vessels (HV). To directly measure O2- production by normal vessels (NV) and HV, we used an assay for O2- based on the chemiluminescence (CL) of lucigenin (L).
Y, Ohara, T E, Peterson, D G, Harrison
openaire   +2 more sources

NH3‐Guided Low‐Temperature Nanostructural Refinement Boosts Visible‐Light‐Driven H2O2 Synthesis in Ionic Carbon Nitrides

Advanced Materials, EarlyView.
A nanostructural refinement strategy is reported for KPHI photocatalysts using NH4Cl in a molten salt environment to induce coherent domain fragmentation and controlled cyano defect formation. This dual modification promotes n→π* transitions, enhances charge separation, and accelerates ORR kinetics, yielding exceptional AQY values of 49% (410 nm) and 5%
Jaya Bharti, Jokotadeola Odutola, Zahra Hajiahmadi, Karlo Nolkemper, Zhihong Tian, Haijian Tong, Vitaliy Shvalagin, Thomas D. Kühne, Tero‐Petri Ruoko, Christian Mark Pelicano   +9 more
wiley   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Incorporating Heavy Atom Effect onto Molecular Rotors for Realizing Exceptionally Photocatalytic Oxidation Reaction under Low‐Temperature Conditions

Advanced Materials Interfaces, EarlyView.
Here, we reported a series of molecular‐rotor‐based photoactivated oxidase mimics, DAPy‐Xm, in which heavy atom incorporation enhances both ROS generation and cold‐adapted property. Among them, DAPy‐Im enables efficient photo‐oxidation of ergosterol and photocatalytic H2O2 production at low temperature.
Barbara Zenabu Anibea, Wen‐Chu Wu, Ching‐Ping Liu, Wei‐Min Liu   +3 more
wiley   +1 more source