Results 91 to 100 of about 640,255 (384)

Parthenolide induces superoxide anion production by stimulating EGF receptor in MDA-MB-231 breast cancer cells. [PDF]

open access: yes, 2013
The sesquiterpene lactone parthenolide (PN) has recently attracted considerable attention because of its anti-microbial, anti-inflammatory and anticancer effects. However, the mechanism of its cytotoxic action on tumor cells remains scarcely defined.
BUTTITTA, Giuseppina   +7 more
core   +1 more source

Enhanced Sonodynamic Bacterial Elimination and Wound Healing Therapy Based on Lanthanide Ion Doped Bi2WO6 Nanosheets and Hydrogel Platform

open access: yesAdvanced Functional Materials, EarlyView.
Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao   +6 more
wiley   +1 more source

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria.

open access: yesBiochemical Journal, 1980
Submitochondrial particles from bovine heart in which NADH dehydrogenase is reduced by either addition of NADH and rotenone or by reversed electron transfer generate 0.9 +/- 0.1 nmol of O2-/min per mg of protein at pH 7.4 and at 30 degrees C.
J. Turrens, A. Boveris
semanticscholar   +1 more source

Nifedipine inhibits superoxide production induced by pulsatile stretch in human aortic endothelial cells [PDF]

open access: yes, 2017
Dihydropiridine calcium channel blocker nifedipine restores nitric oxide-mediated vasodilation in human hypertension. The mechanims involved have not been fully characterized but may relate to endothelial protection.
Cosentino, Francesco   +2 more
core  

Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
Semiconducting polymer nanoparticles (SPNs) exhibit many advantageous optical and biological properties. Multimodal SPN‐based contrast agents that integrate several imaging modalities yield a wealth of information through the use of different imaging mechanisms.
Faysal A. Farah   +3 more
wiley   +1 more source

Alterations in innate immune responses of patients with chronic rhinosinusitis related to cystic fibrosis.

open access: yesPLoS ONE, 2022
The role of phagocytes of children with cystic fibrosis (CF) associated with different phenotypes of chronic rhinosinusitis (CRS) is unclear. The aim of this study was to evaluate the phagocytic capacity of blood neutrophils and monocytes and production ...
Gustavo L Rezende   +7 more
doaj   +1 more source

Amperometric enzyme sensor to check the total antioxidant capacity of several mixed berries. comparison with two other spectrophotometric and fluorimetric methods [PDF]

open access: yes, 2015
The aim of this research was to test the correctness of response of a superoxide dismutase amperometric biosensor used for the purpose of measuring and ranking the total antioxidant capacity of several systematically analysed mixed berries.
CAMPANELLA, Luigi   +4 more
core   +2 more sources

Programmed Aggregation of Lipidated Nitrobenzoselenadiazole as a Photo‐Activatable Pyroptosis Inducer

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents alkylated nitrobenzoselenadiazole (NBSD) photosensitizers that self‐assemble into programmable aggregates, enabling photo‐triggered pyroptosis and enhanced ROS generation. The lead compound, NBSD‐NOc, exhibits superior photodynamic activity, high cellular uptake, and implantable gel compatibility with pH‐responsive release.
Jong Min An   +8 more
wiley   +1 more source

Assessment of the cytotoxicity of chlorhexidine by employing an in vitro mammalian test system

open access: yesJournal of Dental Sciences, 2014
Background/purpose: Chlorhexidine (CHX), a chlorophenyl biguanide with broad antibacterial action, has been widely used in dentistry. The initial uses of CHX in dentistry were to wash operation site and to disinfect root canals. Recently, the addition of
Yi-Ching Li   +4 more
doaj   +1 more source

Superoxide anions enhance platelet adhesion and aggregation [PDF]

open access: yesBritish Journal of Pharmacology, 1989
Superoxide dismutase (SOD, 60 u ml−1) or ferricytochrome c (70 μm) significantly inhibited thrombin‐stimulated platelet adhesion to gelatin‐coated plastic, whereas catalase (1000 u ml−1) or mannitol (1 mm) had no effect. The platelet aggregation induced by low concentrations of thrombin (causing less than 45% maximal change in light transmission) was ...
John R. Vane   +3 more
openaire   +3 more sources

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