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Deciphering the catalytic mechanism of superoxide dismutase activity of carbon dot nanozyme
Superoxide dismutase (SOD) nanozymes show mitigating effect on oxidative stress-related diseases, but are limited by their modest activity. Here, the authors report a carbon dot SOD nanozyme with catalytic activity matching natural enzymes and unveil its
Wenhui Gao+12 more
semanticscholar +1 more source
The cold storage of milt implies potentials alterations in its quality because the storage generates as main process, free radicals that produce spermatozoa membrane lipids damage with the consequent motility and fertilising capacity disruptions.
E. Ibáñez-Arancibia+2 more
doaj +1 more source
Anti-inflammatory effects of secondary metabolites of marine Pseudomonas sp. in human neutrophils are through inhibiting P38 MAPK, JNK, and calcium pathways. [PDF]
Activated neutrophils play a significant role in the pathogenesis of many inflammatory diseases. The metabolites of marine microorganisms are increasingly employed as sources for developing new drugs; however, very few marine drugs have been studied in ...
Shun-Chin Yang+5 more
doaj +1 more source
The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6. The rate of autoxidation increases with increasing pH.
S. Marklund, Gudrun Marklund
semanticscholar +1 more source
Microsomal superoxide anion production and NADPH-oxidation in a series of 22 aziridinylbenzoquinones [PDF]
Several 2,5-bis(1-aziridinyl)-1,4-benzoquinones (BABQs) can be activated to alkylating species by reduction of the quinone moiety. On the other hand, cytotoxicity of these compounds can be induced by redox cycling.
Koster, Andries Sj.+3 more
core +3 more sources
Ursodeoxycholic acid and superoxide anion
To investigate the ability of ursodeoxycholic acid (UDCA) to scavenge superoxide anion (O(2)(-)).We assessed the ability of UDCA to scavenge (O(2)(-)) generated by xanthine-xanthine oxidase (X-XO) in a cell-free system and its effect on the rate of O(2)(-)-induced ascorbic acid (AA) oxidation in hepatic post-mitochondrial supernatants.UDCA at a ...
Predrag Ljubuncic+2 more
openaire +3 more sources
In this work, we measured the effect of cytochrome c on the NADH-dependent superoxide anion production by synaptic plasma membrane vesicles from rat brain.
Alejandro K. Samhan-Arias+5 more
doaj +1 more source
Lipid peroxidation is a nonparenchymal cell event with reperfusion after prolonged liver ischemia [PDF]
A proposed mechanism for irreversible ischemic liver damage has been peroxidation of membrane phospholipids by free radicals. However, the hepatocyte is laden with enzymes which are antioxidants and, therefore, ought to be relatively resistant to ...
Makowka, L+3 more
core +1 more source
Superoxide anions in paraventricular nucleus modulate adipose afferent reflex and sympathetic activity in rats. [PDF]
Adipose afferent reflex (AAR) is a sympatho-excitatory reflex induced by chemical stimulation of white adipose tissue (WAT). Ionotropic glutamate receptors including NMDA receptors (NMDAR) and non-NMDA receptors (non-NMDAR) in paraventricular nucleus ...
Lei Ding+7 more
doaj +1 more source
Background. Histamine is one of the versatile biogenic amines with multiple roles in the immune response and allergic disorders. Histamine and ATP can act as ligands in the body.
Nataliya Harasym+5 more
doaj +1 more source