Results 41 to 50 of about 336,266 (298)

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Aromatic Polyphenol π-π Interactions with Superoxide Radicals Contribute to Radical Scavenging and Can Make Polyphenols Mimic Superoxide Dismutase Activity

Current Issues in Molecular Biology, 2022
Polyphenols are valuable natural antioxidants present in our diet that likely mitigate aging effects, neurodegenerative conditions, and other diseases.
Francesco Caruso, Sandra Incerpi, Jens Pedersen, Stuart Belli, Sarjit Kaur, Miriam Rossi   +5 more
doaj   +1 more source

The Copper Chaperone for Superoxide Dismutase [PDF]

Journal of Biological Chemistry, 1997
Copper is distributed to distinct localizations in the cell through diverse pathways. We demonstrate here that the delivery of copper to copper/zinc superoxide dismutase (SOD1) is mediated through a soluble factor identified as Saccharomyces cerevisiae LYS7 and human CCS (copper chaperone for SOD).
Cizewski Culotta, V., Klomp, L.W.J., Strain, J., Casareno, R.L.B., Krems, B., Gitlin, J.D.   +5 more
openaire   +3 more sources

Efeito da proteina celular do Prion (PrPc) na atividade da enzima superóxido dismutase (SOD) em células vasculares sob estresse oxidativo [PDF]

, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em FarmáciaA proteína celular do prion (PrPC) é expressa em vários tipos celulares, especialmente em neurônios. Sua função fisiológica
Soprana, Hélen Zocche
core  

The tetrazolium dyes MTS and XTT provide new quantitative assays for superoxide and superoxide dismutase

, 1997
The tetrazolium dyes MTS and XTT were reduced to their soluble formazans by superoxide radical anions (O2_) produced by the oxidation of xanthine by xanthine oxidase under standard conditions. These reactions were compared to the well-known reductions of
Sutherland, Mark W., Learmonth, Barbara A.   +1 more
core   +1 more source

Serum antioxidants as predictors of the adult respiratory distress syndrome in septic patients [PDF]

, 1993
Adult respiratory distress syndrome (ARDS) can develop as a complication of various disorders, including sepsis, but it has not been possible to identify which of the patients at risk will develop this serious disorder.
Moore, Frederick A., Parsons, Polly E., Repine, John E., Leff, Jonathan A., Jochum, Marianne, Fritz, Hans, Moore, Eugene E., McCord, Joe M., Taniguchi, Naoyuki, Day, Caroline E.   +9 more
core   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

Characterising the Drosophila extracellular superoxide Dismutase gene

, 2010
The indiscriminate action of reactive oxygen species (ROS), if left unregulated, haslong been considered contributory to a range of disease processes within the animalkingdom and is also a factor associated with ageing.
Blackney, Michael James
core   +1 more source

The influence of cigarette smoking on blood and salivary super oxide dismutase enzyme levels among smokers and nonsmokers—A cross sectional study

Journal of Traditional and Complementary Medicine, 2015
To determine the influence of smoking on blood and salivary superoxide dismutase enzyme levels among smokers, and to demonstrate the significant alterations in the levels of superoxide dismutase in association with patient age, periodontal disease status,
Haziel Diana Jenifer, Sarthak Bhola, Veena Kalburgi, Shivaraj Warad, Vijayalaxmi M. Kokatnur   +4 more
doaj   +1 more source

Molecular characterization of a manganese superoxide dismutase and copper/zinc superoxide dismutase from the mussel Mytilus galloprovincialis

, 2013
The full-length cDNA sequences coding respectively for a manganese superoxide dismutase (Mg-MnSOD) and copper/zinc superoxide dismutase (Mg-CuZnSOD) were cloned from Mytilus galloprovincialis.
Wu, Huifeng, Yuan, Zeyi, Liu, Feng, Wang, Qing, Zhao, Jianmin   +4 more
core   +1 more source