Results 171 to 180 of about 206,917 (252)

Substrate Characterization of Mycobacterial Kinase PknG Revealing PknG‐KARS‐MAPK Phosphorylation Signaling Axis in Host

open access: yesiMetaMed, EarlyView.
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian   +13 more
wiley   +1 more source

Single‐cell transcriptomics reveals cellular heterogeneity and phenotypic transitions of smooth muscle cells in aortic dissection

open access: yesiMeta, EarlyView.
We utilized single‐cell RNA sequencing (scRNA‐seq) to investigate cellular heterogeneity and signaling networks in aortic dissection (AD) tissues compared to adjacent normal tissues. The analysis identified five smooth muscle cell (SMC) subtypes, with SMC2 linked to fibrosis and SMC3 associated with inflammation.
Liang Shao   +12 more
wiley   +1 more source

Strand-Swapped SH3 Domain Dimer with Superoxide Dismutase Activity

open access: yesACS Central Science
Florian R. Häge   +8 more
doaj   +1 more source

Navigating the future of nano‐pesticides: A perspective on design, efficacy, mechanisms, and environmental stewardship

open access: yesiMeta, EarlyView.
Nano‐pesticides are driving a paradigm shift toward sustainable plant protection. This review systematically synthesizes recent advances across four interconnected domains: (i) intelligent formulation design for targeted delivery and controlled release; (ii) interfacial behavior regulation to enhance foliar deposition; (iii) multi‐omics elucidation of ...
Xile Deng   +14 more
wiley   +1 more source

ABCA1 Transporter Is Involved in the Secretion of CuZn Superoxide Dismutase (SOD)-1 by Activated Human T Lymphocytes. [PDF]

open access: yesAntioxidants (Basel)
Carriero F   +12 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

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