Results 201 to 210 of about 206,917 (252)
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Pulmonary Pharmacology & Therapeutics, 2002
In this review we describe the potential role(s) of superoxide in inflammatory disorders.
SALVEMINI D +3 more
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In this review we describe the potential role(s) of superoxide in inflammatory disorders.
SALVEMINI D +3 more
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Extracellular superoxide dismutase
The International Journal of Biochemistry & Cell Biology, 2005The extracellular space is protected from oxidant stress by the antioxidant enzyme extracellular superoxide dismutase (EC-SOD), which is highly expressed in selected tissues including blood vessels, heart, lungs, kidney and placenta. EC-SOD contains a unique heparin-binding domain at its carboxy-terminus that establishes localization to the ...
Eva, Nozik-Grayck +2 more
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SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES
Annual Review of Biochemistry, 1972O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH.. SODs inhibit such HO. production by scavengingO2-, but Cu, ZnSODs, by virtue of a nonspecific peroxidase activity, may peroxidize spin trapping agents and thus give the appearance of catalyzing OH ...
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Microbial Superoxide Dismutases
1989Publisher Summary The presence of oxygen in the environment presents both advantages and threat to all forms of life. The use of oxygen as a final electron acceptor provides more energy than that afforded by anaerobic fermentation. Oxygen is also useful in many biosynthetic reactions.
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Bacterial Superoxide Dismutases
1988Superoxide dismutase (SOD) has played a major role in establishing the biological relevance of oxyradicals. To many oxyradical researchers, “superoxide dismutase” connotes a copper-zinc SOD (CuZnSOD), the first dismutase to be purified and the form of prime interest clinically. However, superoxide dismutases containing manganese or iron as cofactor are
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1996
Abstract The superoxide anion radical (02) is considered to be a highly toxic entity in many biological systems (1–4). It is formed in normal metabolism as well as through the action of many drugs, poisons, and radiation (1–4). It is also involved in radiation damage, DNA damage, phagocytosis, ageing, cancer, etc.
Sara Goldstein, Gidon Czapski
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Abstract The superoxide anion radical (02) is considered to be a highly toxic entity in many biological systems (1–4). It is formed in normal metabolism as well as through the action of many drugs, poisons, and radiation (1–4). It is also involved in radiation damage, DNA damage, phagocytosis, ageing, cancer, etc.
Sara Goldstein, Gidon Czapski
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Superoxide, superoxide dismutase and ischemic injury.
Current opinion in investigational drugs (London, England : 2000), 2002Oxidative stress results from an oxidant/antioxidant imbalance: an excess of oxidants relative to the antioxidant capacity. Recent evidence strongly suggests that oxidant stress plays a major role in several aspects of ischemia and reperfusion. Immunohistochemical and biochemical evidence demonstrate the significant role of reactive oxygen species, in ...
Salvemini, Daniela, CUZZOCREA, Salvatore
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