Results 271 to 280 of about 605,993 (360)

Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic   +4 more
wiley   +1 more source

Cu/Zn-superoxide dismutase naturally fused with a β-propeller lactonase in Deinococcus radiodurans. [PDF]

open access: yesJ Biol Chem
Furukawa Y   +6 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Prophylactic administration of lecithinized superoxide dismutase for a murine model of oxaliplatin-induced myelosuppression. [PDF]

open access: yesFront Pharmacol
Shimoda M   +6 more
europepmc   +1 more source

A non-comparative randomized phase II study of 2 doses of ATN-224, a copper/zinc superoxide dismutase inhibitor, in patients with biochemically recurrent hormone-naïve prostate cancer

open access: green, 2011
Jianqing Lin   +11 more
openalex   +2 more sources

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

Downregulation of Parahippocampal Copper Chaperone for Superoxide Dismutase in Alzheimer's Disease. [PDF]

open access: yesBrain Sci
Sanchez N   +5 more
europepmc   +1 more source

Metal‐Directed Self‐Assembly in a Beta‐Sheet Miniprotein Scaffold

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
A rationally engineered miniprotein, V14C, which is based on the beta β‐sheet Foldon domain, self‐assembles via a metal‐binding site to form well‐defined oligomers in the presence of Zn2+, Hg2+, and Cd2+. This modular design expands the toolbox for creating custom metalloproteins, enabling studies of metal–protein interactions for biochemical functions
Chandan Muni Reddy   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy